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| 1 | α1-antitrypsin increases interleukin-1 receptor antagonist production during pancreatic islet graft transplantation显示文摘尽管为有类型 1 糖尿病的个人的小岛移植被显示了产出优异的血葡萄糖控制,它为长期的控制仍然保持不适当。这是部分,由于小岛损害和压力,那能导致贝它房间损失。过量 IL-1β 的抑制;活动可能最小化小岛损害,因此保存工作。IL-1 受体对手(IL-1Ra ) , IL-1β 的一个内长的禁止者;,保护小岛免受导致 cytokine 的坏死和 apoptosis 的伤害。因此,在 IL-1β 之间的不平衡;并且 IL-1Ra 可能影响到小岛的 allogeneic 和自体免疫的回答的功课。我们的组以前证明传播丝氨酸朊酶禁止者人 alpha-1-antitrypsin (hAAT ) ,以及 immunomodulatory 活动。在现在的学习,我们寻求了决定是否胰腺的小岛 hAAT 的 allograft 保护的活动被 IL-1Ra 调停感应。我们的结果证明 hAAT 在刺激巨噬细胞在 IL-1Ra 表示导致了 2.04 褶层增加并且 hAAT-pre-treated 小岛接枝在 IL-1Ra 抄本层次展出了 4.851 褶层增加,它与中等煽动性的侧面被联系。出人意料地,从 IL-1Ra-knockout 鼠标被孤立并且在 grafting 前与 hAAT 预先对待进野类型的鼠标的小岛在大概从渗入主机房间被导出的 intragraft IL-1Ra 表示产出增加,当主机的 hAAT 处理不在时的虽然。确实, hAAT-pre-treated 小岛产生了能在有教养的巨噬细胞导致 IL-1Ra 生产的 hAAT 免费的调节媒介。最后,我们证明 hAAT 为 p65 支持了不同 phosphorylation 和原子 translocation 模式,为 IL-1Ra 要求的一个关键抄写因素表示。 | Avishag Abecassis Ronen Schuster Galit Shahaf Eyal Ozeri Ross Green David E Ochayon Peleg Rider Eli C Lewis | 2014 | Cellular & Molecular Immunology2014，11，4： | 2 |
| 2 | Autocrine fibroblast growth factor 2 signaling is critical for self-renewal of human multipotent adipose-derived stem cel s显示文摘 | Rider DA Dombrowski C Sawyer AA | | 0，，06： | 1 |
| 3 | Elastic Behavior of a Pseudo-fruit for Determining Bruise Damage to Fruit During Mechanized Handling显示文摘 | RIDER R C FRIDLEY R B BRIEN O M | 1973 | Transaction of the ASAE1973，16，2： | 1 |
| 4 | Cumulative effects of in utero administration of mixtures of 'antiandrogens' on male rat reproductive development 显示文摘 | RIDER C V WILSON V S HOWDESHELL K L | 2009 | Toxicol Pathol2009，37，： | 1 |
| 5 | Radiation pneumonitis: Experience following a large single dose of radiation 显示文摘 | Fryer C J Fitzpatrick P J Rider WD | 1978 | Int J Radiat Oncol Biol Phys1978，4，： | 1 |
| 6 | Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in laboratory rats显示文摘 | Howdeshell K L Rider C V Wilson V S | 2008 | Environ Res2008，108，： | 1 |
| 7 | Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in laboratory rats 显示文摘 | Howdeshell K L Rider C V Wilson V S | 2008 | Environ Res2008，108，： | 1 |
| 8 | PICKLE acts throughout the plant to repress expression of embryonic traits and may play a role in gibberellin-dependent responses 显示文摘 | HENDERSON J T LI H C RIDER S D | 2004 | Plant Physiol2004，134，3： | 1 |
| 9 | Mechanisms of action of phthalate esters, individually and in combination, to induce ab- normal reproductive development in male laboratory rats显示文摘 | Howdeshell K L Rider C V Wilson V S | 2008 | Environ Res2008，108，2： | 1 |
| 10 | Characterization of human recombinant interleukin-2 binding to heparin and heparan sulfate using an ELISA approach 显示文摘 | NAJJAM S R V GIBBS RIDER C C | 1997 | Cytokine1997，9，12： | 1 |
| 11 | Block copolymers under periodic, strong three-dimensional confinement显示文摘 | Arsenault A C Rider D A Tetreault N | 2005 | Journal of the American Chemical Society2005，127，28： | 1 |
| 12 | Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in laboratory rats 显示文摘 | Howdeshell K L Rider C V Wilson V S | 2008 | Environ Res2008，108，： | 1 |
| 13 | Low- phosporous niekel- coated carbon microeoils : Controlling mierostructure through an electroless plating process 显示文摘 | Bi H Kou K C Rider A E | 2009 | Applied Sur- face Science2009，255，15： | 1 |
| 14 | Autocrine fibroblast growth factor 2 increases the multipotentiality of human adipose-derived mesenchymal stem cells显示文摘 | Rider DA Dombrowski C Sawyer AA | 2008 | Stem Cells2008，26，6： | 1 |
| 15 | Influence of adherend surface proparation on bong durability显示文摘 | RIDER A N OLSSON-JACQUES C L ARNOTT D R | 1999 | Surface and Interface Analysis1999，27，： | 1 |
| 16 | Fifteen years after ' Wingspread'--Environmental endocrine disrupters and human and wildlife health: Where we are today and where we need to go 显示文摘 | Hotchkiss A K Rider C V Blystone C R | 2008 | Toxicological Sciences2008，105，2： | 1 |
| 17 | The fungicide propiconazole interferes with embryonic development of the crustacean Daphnia magna 显示文摘 | Kast-Hutcheson K Rider C V Leblanc GA | 2001 | Environ Toxicol Chem2001，20，： | 1 |
| 18 | Cumulative effects of in utero administration of mixturesof“antiandrogens”on male rat reproductive development显示文摘 | RIDER C V WILSON V S HOWDESHEL K L | 2009 | Toxicol Pathol2009，37，1： | 1 |
| 19 | Bonded repairs for carbon/BMI composite at high operating temperatures 显示文摘 | RIDER A N WANG C H CHANG P | 2010 | Composites: Part A2010，，41： | 1 |
| 20 | OCO/GOSAT Preflight Cross-Calibration Experiment 显示文摘 | Sakuma F Bruegge C J Rider D | 2010 | IEEE Transactions on Geoscience and Remote Sensing(S0196-2892)2010，48，1： | 1 |
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