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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Functional outcomes assessment in shoulder surgery显示文摘The effective evaluation and management of orthopaedic conditions including shoulder disorders relies upon understanding the level of disability created by the disease process. Validated outcome measures are critical to the evaluation process. Traditionally, outcome measures have been physician derived objective evaluations including range of motion and radiologic evaluations. However, these measures can marginalize a patient's perception of their disability or outcome. As a result of these limitations, patient self-reported outcomes measures have become popular over the last quarter century and are currently primary tools to evaluate outcomes of treatment. Patient reported outcomes measures can be general health related quality of life measures, health utility measures, region specific health related quality of life measures or condition specific measures. Several patients self-reported outcomes measures have been developed and validated for evaluating patients with shoulder disorders. Computer adaptive testing will likely play an important role in the arsenal of measures used to evaluate shoulder patients in the future. The purpose of this article is to review the general health related quality-of-life measures as well as the jointspecific and condition specific measures utilized in evaluating patients with shoulder conditions. Advancesin computer adaptive testing as it relates to assessing dysfunction in shoulder conditions will also be reviewed. | James D Wylie James T Beckmann Erin Granger Robert Z Tashjian | 2014 | World Journal of Orthopedics2014，5，5： | 2 |
| 3 | Adipocyte iron regulates adiponectin and insulin sensitivity显示文摘 | Gabrielsen J Scott Gao Yan Simcox Judith A Huang Jingyu Thorup David Jones Deborah Cooksey Robert C Gabrielsen David Adams Ted D Hunt Steven C Hopkins Paul N Cefalu William T McClain Donald A | 2012 | EN2012，，10： | 2 |
| 4 | Hyper-X Post-Flight Trajectory Reconstruction显示文摘 | Christopher D K Paul V T Robert C B | 2006 | Journal of Spacecraft and Rockets2006，43，1： | 1 |
| 5 | A comparison of the low moisture content limit to the logarithmic relation between seed moisture content and longevity in twelve species显示文摘 | Ellis R H Hong T D Roberts E H | 1989 | Annals of Botany1989，，63： | 1 |
| 6 | Employee research is a powerful tool in leading the time-based organization显示文摘 | Roberts D R and Rollins T | 1995 | Employee Relations Today1995，22，4： | 1 |
| 7 | Bacterial RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited condition 显示文摘 | Paolo C Dave W Robert J B Don C A Jay H Martin S Mark A Ganesh K Sara S Robert D Santiago N Stephanie B Mary F Jayaprakash T Santanu D Christopher B Michael H L Jacqueline E H | 2008 | Plant Physiology2008，147，2： | 1 |
| 8 | Compatibility of Beauveria bassiana iso- lates with insecticide formulations used in colorado potato beetle (Coleop- tera: Chrysomelidae ) control 显示文摘 | ] ANDERSON T E ROBERTS W D | 1983 | Econ Entomol1983，76，4： | 1 |
| 9 | Image quality of sparse -aperture designs for remote sensing显示文摘 | Robert D F Theodore A T Jason R C | 2002 | Optical Engineering2002，41，8： | 1 |
| 10 | A low-moisture-content limit to logarithmic relation between seed moisture content and longevity显示文摘 | Ellis R H Hong T D Roberts E H | 1989 | Annals of Botany1989，61，： | 1 |
| 11 | Syn- thesis of Isoambrettolide and Its Isomers from 1,9-cy- clohexadecadiene显示文摘 | BRAJA D M ROBERT W T RAMAN R P | 1972 | J Org Chem1972，37，24： | 1 |
| 12 | Low moisture content limit to relation between seed longevity and moisture显示文摘 | Ellis R H Hong T D Roberts E H | 1990 | Annals of Botany1990，，65： | 1 |
| 13 | Estimation of sucrose esters(E473) in foods using gas chromatography-mass spectrometry 显示文摘 | Scottera M J Castlea L Roberts D P T | 2006 | Food Additives and Contaminants2006，23，6： | 1 |
| 14 | Analysis of the human type I insulin - like growth factor receptor promoter region 显示文摘 | Cooke D W Bankert L A Roberts C T Jr | 1991 | Biochemical and Biophysical Research Communications1991，177，3： | 1 |
| 15 | Factors influencing views of patients with gynecologic cancer about end-of-life decisions 显示文摘 | Roberts JA Brown D Elkins T | 1997 | Am J Obstet Gynecol1997，176，11： | 1 |
| 16 | Pediatric drug labeling:improving the safety and efficacy of pediatric therapies显示文摘 | Roberts R Rodriguez W Murphy D Crescenzi T | 2003 | JAMA2003，290，7： | 1 |
| 17 | Low moisture content limits or relation between seed longevity and moisture显示文摘 | Ellis R H Hong T D Roberts E H | 1990 | Annals of Botany1990，，65： | 1 |
| 18 | Moisture content and the longevity of seeds of Phascolus vulgaris 显示文摘 | Ellis R H Hong T D Roberts E H | 1990 | Annals of Botany1990，，66： | 1 |
| 19 | How nematode sperm crawl显示文摘 | Bottino D Mogilner A Roberts T | 2002 | Journal of Cell Science2002，115，： | 1 |
| 20 | Compatibility of Beauveria bassiana isolates with insecticide formulations used in colorado potato beetle (Coleoptera: Chrysomelidae) control 显示文摘 | ANDERSON T E ROBERTS W D | 1983 | J Econ Entomol1983，76，： | 1 |
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