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| 1 | Pathophysiology of cerebral oedema in acute liver failure显示文摘Cerebral oedema is a devastating consequence of acute liver failure(ALF)and may be associated with the development of intracranial hypertension and death.In ALF,some patients may develop cerebral oedema and increased intracranial pressure but progression to lifethreatening intracranial hypertension is less frequent than previously described,complicating less than one third of cases who have proceeded to coma since the advent of improved clinical care.The rapid onset of encephalopathy may be dramatic with the development of asterixis,delirium,seizures and coma.Cytotoxic and vasogenic oedema mechanisms have been implicated with a preponderance of experimental data favouring a cytotoxic mechanism.Astrocyte swelling is the most consistent neuropathological finding in humans with ALF and ammonia plays a definitive role in the development of cytotoxic brain oedema.The mechanism(s)by which ammonia induces astrocyte swelling remains unclear but glutamine accumulation within astrocytes has led to the osmolyte hypothesis.Current evidence also supports an alternate‘Trojan horse’hypothesis,with glutamine as a carrier of ammonia into mitochondria,where its accumulation results in oxidative stress,energy failure and ultimately astrocyte swelling.Although a complete breakdown of the blood-brain barrier is not evident in human ALF,increased permeation to water and other small molecules such as ammonia has been demonstrated resulting from subtle alterations in the protein composition of paracellular tight junctions.At present,there is no fully efficacious therapy for cerebral oedema other than liver transplantation and this reflects our incomplete knowledge of the precise mechanisms underlying this process which remain largely unknown. | Teresa R Scott Victoria T Kronsten Robin D Hughes Debbie L Shawcross | 2013 | World Journal of Gastroenterology2013，19，48： | 8 |
| 2 | Precision atomic gravimeter based on Bragg diffraction显示文摘 | P A Altin M T Johnsson V Negnevitsky G R Dennis R P Anderson J E Debs S S Szigeti K S Hardman S Bennetts G D McDonald L D Turner J D Close N P Robins | 2013 | New Journal of Physics2013，，2： | 2 |
| 3 | Prevalence of verocytotoxigenieEshehefiehia coil serotype 01, I:H7 in children with diarrhoea attendingaSydney hospital显示文摘 | Ony J Zhe L Robins Browne R | 1993 | Jpaediatr Child Health1993，29，3： | 1 |
| 4 | Spatial variability of strontium distribution coefficients and their correlation with hydraulic conductivity in the Canadian Forces Air Base Borden aquifer 显示文摘 | ROBIN M J L SUDICKY E A GILLHAM R W | 1991 | Water Resour Res1991，27，10： | 1 |
| 5 | Two SEM techniquesto investigate reservoir-rock wettability显示文摘 | ROBIN M COMBES R CUIEC L | 1998 | Journal ofpetroleum technology1998，50，11： | 1 |
| 6 | Molecularpaleohydrology: Interpreting the hydrogen isotopiccomposition of lipid biomarkers from photosynthesizing organisms 显示文摘 | Sachse D Billault I Bowen G Y Chikaraishi Y Dawson T E Feakins S J Freeman K H Magill C R McInerney F A vander Meer M T J Polissar P Robins R J Sachs J P Schmidt HL Sessions A L White J W C West J B Kahmen A | 2012 | Ann Rev Earth Planet Sci2012，40，： | 1 |
| 7 | Corrosion behavior of the Ti-4% A1-4% V alloy inboiling nitric acid solutions 显示文摘 | Robin A Sandim H R Z Rosa J L | 1999 | Corrosion Science1999，41，7： | 1 |
| 8 | Genetic mapping of persistence in tetraploid alfalfa显示文摘 | Robins J G Hansen J L Viands D R | 2008 | Crop Science2008，48，： | 1 |
| 9 | Implicit self-theories in the academic domain: Implications for goal orientation, attributions, affect, and self-esteem change显示文摘 | Robins R W Pals J L | 2002 | Self and Identity2002，1，4： | 1 |
| 10 | Conceptu- alizing and Assessing Self-Enhancement Bias:A Compo- nential Approach 显示文摘 | V S Y Kwan O P John R W Robins L L Kuang | 2008 | Journal of Personality and Social Psy- chology2008，94，6： | 1 |
| 11 | Gastro 2013 AP- DW/WCOG Shanghai Working Party Report:Chronic diar- rhea: Definition, classification, diagnosis 显示文摘 | Schiller L R Pardi D S Robin S | 2014 | Journal of Gastroenterology & Hepatology2014，29，1： | 1 |
| 12 | Environmental impacts of dredging on seagrasses:A review 显示文摘 | ERFTEMEIJER P L A ROBIN LEWIS III R R | 2006 | Marine Pollu- tion Bulletin2006，52，： | 1 |
| 13 | Two replicable suppressor situations in personality research显示文摘 | Paulhus D L Robins R W Trzesniewski K H | 2004 | Multivariate Be- havioral Research2004，39，2： | 1 |
| 14 | Impression management: A literature review and two-component model 显示文摘 | Mark R L Robin Kowalski | 1990 | Psychological Bulletin1990，107，1： | 1 |
| 15 | Morphology and ultrastructure of lymphocystis disease virus, a fish iridovirus, grown in tissue culture显示文摘 | Berthiaume L Alain R Robin J | 1984 | Virology1984，135，1： | 1 |
| 16 | The stem cell marker CD133 associates with enhanced' colony formation and cell motility ifi colorectal cancer 显示文摘 | ELSABA T M MARTINEZ-POMARES L ROBINS A R | 2010 | PLoS One2010，5，10： | 1 |
| 17 | Public opinion about condoms for HIV and STD prevention显示文摘 | William L Y Robin R M Richard A C | 2005 | Perspect Sex Reprod Health2005，37，3： | 1 |
| 18 | Disentangling the effects of low self - esteem and stressful events on depression : findings from three longitudinal studies显示文摘 | Orth U Robins R W Meier L L | 2009 | Journal of personality and social psychology2009，97，2： | 1 |
| 19 | Personality Correlates of Self - Esteem显示文摘 | R W Robins J L Tracy K Trzesniewski J Potter & S D Gosling | 2001 | Journal of Research in Personality2001，，35： | 1 |
| 20 | Prevalence of verocytotoxigenic Eshcherichia coli serotype O154:H7 in children with diarrhea attending a Sydney hospital显示文摘 | ONG J ZHE L ROBINS B R | 1993 | J Paediatr Child Health1993，29，3： | 1 |
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