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567篇 您的检索式:作者名="Rowlands S"
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1Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma显示文摘The major type of human liver cancer is hepatocellular carcinoma(HCC), and there are currently many risk factors that contribute to this deadly disease. The majority of HCC occurrences are associated with chronic hepatitis viral infection, and hepatitis B viral(HBV) infection is currently a major health problem in Eastern Asia. Elucidating the genetic mechanisms associated with HBV-induced HCC has been difficult due to the heterogeneity and genetic complexity associated with this disease. A repertoire of animal models has been broadly used to study the pathophysiology and to develop potential treatment regimens for HBVassociated HCC. The use of these animal models has provided valuable genetic information and has been an important contributor to uncovering the factors involved in liver malignant transformation, invasion and metastasis. Recently, transposon-based mouse models are becoming more widely used in liver cancer research to interrogate the genome by forward genetics and also used to validate genes rapidly in a reverse genetic manner. Importantly, these transposon-based rapid reverse genetic mouse models could become crucial in testing potential therapeutic agents before proceeding to clinical trials in human. Therefore, this review will cover the use of transposon-based mouse models toaddress the problems of liver cancer, especially HBVassociated HCC occurrences in Asia.Amy P Chiu Barbara R Tschida Lilian H Lo Branden S Moriarity Dewi K Rowlands David A Largaespada Vincent W Keng 2015World Journal of Gastroenterology2015,21,42:2
2Microbial degradation of aromatic components of crudes oils:a comparison of laboratory and field observations 显示文摘Rowland S J 1986Organic Geochemistry1986,9,4:1
3Genetic analysis of tolerance in blueberry(Vaccinium section Cyanococcus)显示文摘Arora R Rowland L J Lehmann J S 2000690-6962000,,:1
4Stratospheric sink for chlorofluorometh- anes: Chlorine atomc-atalysed detruction of ozone 显示文摘Molina M J Rowland F S 1974Nature1974,249,:1
5Biodegradation of aromatic hydrocarbons in crudes oils from the Barrow Sub-basin of Western Australia显示文摘Volkman J K Alexander R Kagi R I Rowland S J Sheppard P N 1984Org Geochem1984,6,62:1
6The primary neutralization epitope of porcine respiratory and reproductive syndrome virus strain VR-2332 is located in the middle of the GP5 ectodomain 显示文摘Plagemann P G Rowland R R Faaberg K S 2002Arch Virol2002,147,12:1
7All foot and mouth disease virus serotypes initiate protein synthesis at two separate AUGs显示文摘Sangar D Newton S Rowlands D 1987Nucleic Acids Res1987,15,:1
8Effects of stocking density on the performance of the Australian freshwater silver perch (Bidyanus bidyanus) in cages显示文摘Rowland S J Mifsud C Nixon M 2006Aquaculture2006,253,30:1
9Identification of four gene variants associated with myocardial infarction显示文摘Shiffman D Ellis S G Rowland C M 2005Am J Hum Genet2005,77,4:1
10T-1ymphocyte transformation in experimental obstructive jaundice:the role of serum-suppressive factors显示文摘Thompson RLE Ranjbar S Rowlands BJ 1993World J Surg1993,17,6:1
11Electrical and material characterization of field-aged 400 kV silicone rubber composite insulators显示文摘Rowland S M Robertson J Xiong Y 2010IEEE Trans on Dielectrics and Electrical Insulation2010,17,2:1
12Electrical and material characterization of field-aged 400 kV silicone rubber composite insulators显示文摘Rowland S Robertson J Xiong Y 2010IEEE Transactions on Dielectrics and Electrical Insulation2010,17,2:1
13Electrical and Material Characterization of Field-aged 400kV Silicone Rubber Composite Insulators显示文摘Rowland S M Robertson J Xiong Y 2010IEEE Transactions on Di- electrics and Electrical Insulation2010,17,2:1
14Microbial degradation of aromatic components of crude oils:a comparison of laboratory and field observations显示文摘Rowland S J Alexander R Kagi R I 1986Organic Geochemistry1986,9,:1
15Uptake of the pharmaceutical fluoxetine hydrochloride from growth medium by Brassicaceae显示文摘Redshawa C H Wootton V G Rowland S J 2008Phytochemistry2008,69,13:1
16Resonance-induced hydrogen bonding at sulfur acceptors in RtRzC = S and R~ CSE-systems 显示文摘ALLEN F H BIRD C M ROWLAND R S 1997Acta Cryst1997,53,4:1
17CFCs in the environment显示文摘Molina M J Rowland F S 1974Nature1974,,8:1
18Stratospheric sink for chlorofluormoethanes:chlorine atom-catalyzed destruction of ozone显示文摘Molina M J Rowland F S 1974Nature1974,249,5640:1
19New A- nalysis of Lunar Prospector Radio Tracking Data Brings the Nearside Gravity Field of the Moon with an Unprecedented Resolution显示文摘Han S C Mazarico E Rowlands D 2011Icarus2011,215,2:1
20Development of ESTPCR markers for DNA fingerprinting and genetic relationship studies in blueberry显示文摘Rowland L J Mehra S Dhanaraj A 2003J Amer Soc Hort Sci2003,128,:1
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