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| 1 | One hundred and seventy-eight consecutive pancreatoduodenectomies without mortality:role of the multidisciplinary approach显示文摘BACKGROUND:Pancreatoduodenectomy offers the only chance of cure for patients with periampullary cancers.This,however,is a major undertaking in most patients and is associated with a significant morbidity and mortality.A multidisciplinary approach to the workup and follow-up of patients undergoing pancreatoduodenectomy was initiated at our institution to improve the diagnosis,resection rate,mortality and morbidity.We undertook the study to assess the effect of this approach on diagnosis,resection rates and short-term outcomes such as morbidity and mortality.METHODS:A prospective database of patients presenting with periampullary cancers to a single surgeon between April 2004 and April 2010 was reviewed.All cases were discussed at a multidisciplinary meeting comprising surgeons,gastroenterologists,radiologists,oncologists,radiation oncologists,pathologists and nursing staff.A standardized investigation and management algorithm was followed.Complications were graded according to the Clavien-Dindo classification.RESULTS:A total of 295 patients with a periampullary lesion were discussed and 178 underwent pancreatoduodenectomy (resection rate 60%).Sixty-one patients (34%) required either a vascular or an additional organ resection.Eighty-nine patients experienced complications,of which the commonest was blood transfusion (12%).Thirty-four patients (19%) had major complications,i.e.grade 3 or above.There was no in-hospital,30-day or 60-day mortality.CONCLUSIONS:Pancreatoduodenectomy can safely be performed in high-volume centers with very low mortality.The surgeon's role should be careful patient selection,intensive preoperative investigations,use of a team approach,and an unbiased discussion at a multidisciplinary meeting to optimize the outcome in these patients. | Jaswinder S Samra Raul Alvarado Bachmann Julian Choi Anthony Gill Michael Neale Vikram Puttaswamy Cameron Bell Ian Norton Sarah Cho Steven Blome Ritchie Maher Sivakumar Gananadha Thomas J Hugh | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，4： | 8 |
| 2 | Desulfurization of model FCC feedstocks by alkylation:Transformation of thiophenic compounds in presence of 2-methyl-1-pentene over acidic zeolites显示文摘 | DUPUY B LAFORGE S BACHMANN C MAGNOUX P RICHARD F | 2012 | J Mol Catal A:Chem2012，，： | 1 |
| 3 | Unsu- pervised BCM projection pursuit algorithms for classification of simulated radar presentation显示文摘 | BACHMANN C M MUSMAN S A LUONG D etal | 1994 | Neural Networks1994，7，4： | 1 |
| 4 | Visibility : Science and Regulation显示文摘 | CHOW J C BACHMANN J D WIERMAN S S G | 2002 | Journal of the Air and Waste Management Association2002，52，9： | 1 |
| 5 | Comparison of fluorode oxyglucose positron emission tomography and'conventional diagnostic procedures'for the detetion of distant metastases in breast cancer patient显示文摘 | Dose J Bleckmann C Bachmann S | 2002 | Nucl Med Commun2002，23，9： | 1 |
| 6 | Protective properties of inhaled IL-22 in a model of ventilator-induced lung injury显示文摘 | Hoegl S Bachmann M Scheiermann P | 2011 | Am J Respir Cell Mol Biol2011，44，： | 1 |
| 7 | Increased epithelial cell proliferation and abnormal extracellular matrix in rat polycystic kidney disease显示文摘 | Ramasubbu K Gretz N Bachmann S | 1998 | J Am Soc Nephrol1998，9，： | 1 |
| 8 | The effects of oral N- acetylcysteine in chronic bronchitis: a quantitative systematic review显示文摘 | Stey C Steurer J Bachmann S | 2000 | Eur Respir J2000，16，2： | 1 |
| 9 | Retroviral R- NA identified in the cerebrospinal fluids and brains of individuals with schizophrenia显示文摘 | KARLSSON H BACHMANN S CHRODER J | 2001 | Proc Natl Acad Sci USA2001，98，8： | 1 |
| 10 | Unsupervised BCM projection pursuit algorithms for classification of simulated radar presentation 显示文摘 | Bachmann C M Musman S A Luong D | 1994 | Neural Networks1994，7，4： | 1 |
| 11 | Crystal structure of N, N, N-tris amine-manganese (llI ) , Mn 显示文摘 | Steinhauser S Bachmann F Hazenkamp M | 2004 | NCS2004，，： | 1 |
| 12 | Molecular and functional analysis of the Epstein-Barr virus LMP1 oncogene promoter in lymphoproliferative diseases显示文摘 | Rothenberger S Bachmann E Knecht H | 1997 | Exp Hematol1997，25，13： | 1 |
| 13 | The volatile an-esthetic sevoflurane inhibits activation of neutrophil granulo-cytes during simulated extracorporeal circulation 显示文摘 | Schmid E Krajewski S Bachmann D | 2012 | Int Im-munopharmacol2012，14，2： | 1 |
| 14 | Estrogen directly ac- tivates AID transcription and function显示文摘 | Pauklin S Sernandez I Bachmann G | 2009 | J Exp Med2009，206，1： | 1 |
| 15 | Photoselective vaporization of the prostate(Green Light PV):lessons learnt after 3500 procedures显示文摘 | Gomez S F Bachmann A Choi B B | 2010 | Prostate Cancer Prostatic Dis2010，10，4： | 1 |
| 16 | Mice are protected from Helicobacter pylori infection by nasal immunization with attenuated Salmonella typhimurium phoP^c expressing urease A and B subunits显示文摘 | Corthesy-Theulaz IE Hopkins S Bachmann D | 1998 | Infect Immun1998，66，2： | 1 |
| 17 | Comparison of fluorodeoxyglucose positron emis-sion tomography and 'conventional diagno stic procedures' for the detection of distant metastases in breast cancer patients显示文摘 | Dose J Bleckmann C Bachmann S | 2002 | Nucl Med Common2002，23，9： | 1 |
| 18 | Charge amplification and transfer processes in the gas electron multiplier 显示文摘 | Bachmann S | 1999 | Nucl Instrum Methods1999，438，： | 1 |
| 19 | Protective of inhaled IL-22 in a model of ventilatorindueed lung injury 显示文摘 | Hoegl S Bachmann M Seheiermann P | 2011 | Am J Respir Cell Mol Biol2011，44，3： | 1 |
| 20 | Unsu-pervised BCM projection pursuit algorithms for classification ofsimulated radar presentations 显示文摘 | BACHMANN C M MUSMAN S A LUONG D | 1994 | Neural Networks1994，7，4： | 1 |
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