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| 1 | Early palliative care for patients with metastatic non-small-cell lung cancer显示文摘Comments This landmark article demonstrates that integration of early palliative care with standard oncologic practice shortly after diagnosis may improve quality of life,mood,and overall survival for adults with advanced non-small-cell lung cancer(NSCLC).If validated,these findings could support a paradigm shift in the care of adults with metastatic NSCLC and possibly patients with other tumor types characterized by short survival and high symptom burden. | Temel JS Greer JA Muzikansky A Gallagher ER Admane S Jackson VA Dahlin CM Blinderman CD Jacobsen J Pirl WF Billings JA Lynch TJ | 2010 | 中国肺癌杂志2010，13，9： | 165 |
| 2 | 年龄>80岁患者的收缩压轨迹、衰弱和全因死亡率:电子健康记录队列研究显示文摘血压随年龄而升高,老年人高血压患病率较高。收缩压升高可能是老年人心血管病的最重要危险因素。最近几项大型临床试验显示,降压药降低血压的同时可降低老年人的心血管事件和死亡率。对年龄〉80岁患者进行降压治疗的老老年高血压试验(hypertension in the very elderly trial, | Ravindrarajah R Hazra NC Hamada S Charlton J Jackson SHD Dregan A Gulliford MC 练桂丽 叶鹏 | 2017 | 中华高血压杂志2017，25，7： | 22 |
| 3 | Effects of alkaline-electrolyzed and hydrogen-rich water,in a high-fat-diet nonalcoholic fatty liver disease mouse model显示文摘AIM To identify the effect of hydrogen-rich water(HRW) and electrolyzed-alkaline water(EAW) on high-fat-induced non-alcoholic fatty acid disease in mice.METHODS Mice were divided into four groups:(1) Regular diet(RD)/regular water(RW);(2) high-fat diet(HFD)/RW;(3) RD/EAW; and(4) HFD/EAW. Weight and body composition were measured. After twelve weeks, animals were sacrificed, and livers were processed for histology and reverse-transcriptase polymerase chain reaction. A similar experiment was performed using HRW to determine the influence and importance of molecular hydrogen(H2) in EAW. Finally, we compared the response of hepatocytes isolated from mice drinking HRW or RW to palmitate overload.RESULTS EAW had several properties important to the study:(1) pH = 11;(2) oxidation-reduction potential of-495 mV; and(3) H2 = 0.2 mg/L. However, in contrast to other studies, there were no differences between the groups drinking EAW or RW in either the RD or HFD groups. We hypothesized that the null result was due to low H2 concentrations. Therefore, we evaluated the effects of RW and low and high HRW concentrations(L-HRW = 0.3 mg H2/L and H-HRW = 0.8 mg H2/L, respectively) in mice fed an HFD. Compared to RW and L-HRW, H-HRW resulted in a lower increase in fat mass(46% vs 61%), an increase in lean body mass(42% vs 28%), and a decrease in hepatic lipid accumulation(P < 0.01). Lastly, exposure of hepatocytes isolated from mice drinking H-HRW to palmitate overload demonstrated a protective effect from H2 by reducing hepatocyte lipid accumulation in comparison to mice drinking regular water.CONCLUSION H2 is the therapeutic agent in electrolyzed-alkaline water and attenuates HFD-induced nonalcoholic fatty liver disease in mice. | Karen Jackson Noa Dressler Rotem S Ben-Shushan Ari Meerson Tyler W LeBaron Snait Tamir | 2018 | World Journal of Gastroenterology2018，24，45： | 9 |
| 4 | Systematic review and meta-analysis of esophageal cancer in Africa:Epidemiology, risk factors, management and outcomes显示文摘BACKGROUND Esophageal cancer(EC)is associated with a poor prognosis,particularly so in Africa where an alarmingly high mortality to incidence ratio prevails for this disease.AIM To provide further understanding of EC in the context of the unique cultural and genetic diversity,and socio-economic challenges faced on the African continent.METHODS We performed a systematic review of studies from Africa to obtain data on epidemiology,risk factors,management and outcomes of EC.A non-systematic review was used to obtain incidence data from the International Agency for Research on Cancer,and the Cancer in Sub-Saharan reports.We searched EMBASE,PubMed,Web of Science,and Cochrane Central from inception to March 2019 and reviewed the list of articles retrieved.Random effects metaanalyses were used to assess heterogeneity between studies and to obtain odds ratio(OR)of the associations between EC and risk factors;and incidence rate ratios for EC between sexes with their respective 95%confidence intervals(CI).RESULTS The incidence of EC is higher in males than females,except in North Africa where it is similar for both sexes.The highest age-standardized rate is from Malawi(30.3 and 19.4 cases/year/100000 population for males and females,respectively)followed by Kenya(28.7 cases/year/100000 population for both sexes).The incidence of EC rises sharply after the age of 40 years and reaches a peak at 75 years old.Meta-analysis shows a strong association with tobacco(OR 3.15,95%CI:2.83-3.50).There was significant heterogeneity between studies on alcohol consumption(OR 2.28,95%CI:1.94-2.65)and on low socioeconomic status(OR 139,95%CI:1.25-1.54)as risk factors,but these could also contribute to increasing the incidence of EC.The best treatment outcomes were with esophagectomy with survival rates of 76.6%at 3 years,and chemo-radiotherapy with an overall combined survival time of 267.50 d.CONCLUSION Africa has high incidence and mortality rates of EC,with preventable and nonmodifiable risk factors.Men in this setting are at increased risk due to their higher prevalence of tobacco and alcohol consumption.Management requires a multidisciplinary approach,and survival is significantly improved in the setting of esophagectomy and chemoradiation therapy. | Akwi W Asombang Nathaniel Chishinga Alick Nkhoma Jackson Chipaila Bright Nsokolo Martha Manda-Mapalo Joao Filipe G Montiero Lewis Banda Kulwinder S Dua | 2019 | World Journal of Gastroenterology2019，25，31： | 9 |
| 5 | Quartz isolation from rocks, sediments and soils for determination of oxygen isotopes composition显示文摘 | Syers J K Chapman S L Jackson M L | 1968 | Geochimica et Cosmochimica Acta1968，32，： | 2 |
| 6 | 脊髓损伤后残存自主神经功能载录国际标准显示文摘近年来,脊髓损伤神经学分类园际标准(International Stand- ards for the Neurological Classification of Spinal Cord Injury, ISNCSCI)被用来记载脊髓损伤后运动和感觉功能的损害,目前该标准已是第六版。1992年第一份国际认可的标准出版时,曾进行了较大的修订,修订内容包括完全性损伤与不完全性损伤的定义, | MS Alexander AB Jackson W Donovan DE Graves SL Elliott A Krassioukov AW Sheel I Estoresl B Green A Gousse NL Braekett D Cardenas M Kennelly A-K Karlason F Biering-Sorensen K Krogh T Linsenmeyer R Marino J Ditunno CJ Mathias I Perkash G Creasey G Schilero J Wecht B Schurch V Dietz J Sonksen S Stiens D Bodner LA Wuermser J-J Wyndaele 周谋望 刘楠 S Charlifue | 2010 | 中华物理医学与康复杂志2010，32，4： | 2 |
| 7 | Twin birth after subzonal insemination 显示文摘 | Fishcl S Antinori S Jackson P | 1990 | Lancet1990，，1： | 1 |
| 8 | Digital mapping of bacterial artificial chromosomes by fluorescence in situ hybridization显示文摘 | Jackson S A Dang F Jiang J | 1999 | Plant J1999，17，5： | 1 |
| 9 | Wheat Canopy Temperature:A Practical Tool for Evaluating Water Requirements显示文摘 | Reginato R J Idso S B | 1977 | Water Resour Res1977，13，： | 1 |
| 10 | A new insight into the gelatinization process of native starches显示文摘 | Wajira S Ratnayake David S Jackson | 2007 | Carbohydrate Polymers2007，67，： | 1 |
| 11 | Diagnosis of invasive amebiasis by enzyme-linked immunosorbent assay of saliva to detect amebic lectin antigen and anti-lectin immunoglobulin G antibodies显示文摘 | ABD-ALLA M D JACKSON T REDDY S | 2000 | J Clin Microbiol2000，38，6： | 1 |
| 12 | In vitro migration of cytotroph- oblasts through a decidual endothelial monolayer: the role of matrix metalloproteinases 显示文摘 | Campbell S Rowe J Jackson C J | 2003 | Placenta2003，24，： | 1 |
| 13 | Culture of skin cells in 3D rather than 2D improves their ability to survive exposure to cytotoxic agents显示文摘 | Sun T Jackson S Haycock J W | 2006 | Journal of Biotechnology2006，122，3： | 1 |
| 14 | Oxidant-mediated repression of mitochondrial transcription in diabetic rats显示文摘 | Kristal B Koopmans S Jackson C T | 1997 | Free Rad Biol Med1997，22，： | 1 |
| 15 | Canopy temperature as a crop water stress indicator显示文摘 | Jackson R D Idso S B Reginato R J | 1981 | Water recourses research1981，17，4： | 1 |
| 16 | Theoretical Modeling of Tm-doped Silica Fibre Lasers显示文摘 | Jackson S D King T A | 2003 | Journal of Lightwave Technology2003，17，5： | 1 |
| 17 | Toward a conceptual understanding of the flow experience in elite athletes 显示文摘 | Jackson S A | 1996 | Research Quarterly for Exercise and Sport1996，67，3： | 1 |
| 18 | Psychological correlates of flow in sport显示文摘 | Jackson S A Kiniecik j C Ford S | 1998 | Journal of Sport and Exercise Psychology1998，20，3： | 1 |
| 19 | Restoring forest landscapes显示文摘 | Maginnis S Jackson W | 2002 | ITTO Tropical Forest Update2002，12，4： | 1 |
| 20 | Control procedures for residuals associated with Principal Component Analysis显示文摘 | Jackson J E Mudholkar G S | 1979 | Technometrics1979，，： | 1 |
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