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| 1 | 科学传播的一种当代定义显示文摘 科学传播是一个方兴未艾的实践和研究领域.在过去的20多年间,科学传播活动、课程和从业者的数量稳步上升.…… | T.W.伯恩斯 D.J.奥康纳 S.M.斯托克麦耶 李曦 | 2007 | 科普研究2007，2，6： | 32 |
| 2 | Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, and inhibits the proliferation of human gastric cancer cells in vitro显示文摘Gastrin and cyclooxygenase-2(COX-2) playimportant roles in the carcinogenesis and progression ofgastric cancer.However,it remains unknown whether the combination of cholecystokinin-2(CCK-2) receptor antagonist plus COX-2 inhibitor exerts synergistic anti-tumor effects on human gastric cancer.Here,we demonstrated that the combination of AG-041R(a CCK-2 receptor antagonist) plus NS-398(a selective COX-2 inhibitor) treatment had synergistic effects on proliferation inhibition,apoptosis induction,down-regulation of Bcl-2 and up-regulation of Bax expression in MKN-45 cells.These results indicate that simultaneous targeting of CCK-2 receptor and COX-2 may inhibit gastric cancer development more effectively than targeting either molecule alone.(C)2008 Elsevier Ireland Ltd.All rights reserved. | Sun, W. H. | 2008 | 南京医科大学学报(自然科学版)2008，28，9： | 30 |
| 3 | 华南奥陶系达瑞威尔阶底界附近的牙形刺显示文摘本文详细描述了湖北宜昌、兴山和浙赣“三山”(即浙江的常山、江山和江西的玉山)地区奥陶系达瑞威尔阶底界附近层位中的牙形刺共21属32种。以带分子的首次出现为标志,湖北地区达瑞威尔阶底界上、下地层的牙形刺带由上而下可划分为:Eoplacognathuscrassus,Lenodusvariabilis,L.antivariabilis,Baltoniodusnorrlandicus-Microzarkodinaparva和Paroistodusoriginalis带。这些牙形刺带可与Lindstrom(1971)、Lofgren(1978,1993,1994,1995)、Wang和Bergstrom(1995)、Bagnoli和Stouge(1997)及Albanesi等(1998)在欧洲、我国浙赣“三山”地区及阿根廷等地发现的牙形刺带进行对比(表1)。在湖北宜昌和兴山地区U.austrodentatus笔石带之底界(=达瑞威尔阶之底界)十分接近Baltoniodusnorrlandicus-Microzarkodinaparva带之底界。 | 王志浩 S.M.伯格斯特龙 | 1999 | 微体古生物学报1999，16，4： | 22 |
| 4 | 超声心动图法测定肺动脉收缩压的可靠性和存在问题显示文摘目的 与有创的导管法对照 ,评价多普勒超声心动图法测定肺动脉高压患者肺动脉收缩压的可靠性和存在的问题 .方法 临床诊断为原发性肺动脉高压患者 73例 ,右心导管法实时监测右房、室压及肺动脉压 ,同时进行超声多普勒检查 ,测量三尖瓣最大返流速度 ,计算右房、室间压差 (Δp) ,并与心导管法测量结果进行相关性分析 .注意分析超声心动图法测定过程中出现的问题并讨论解决方法 .结果 多普勒超声心动图法测定的 Δp与导管法测定结果无显著差别 [(12 .6± 3.2 ) k Pa vs(12 .2± 3.1) k Pa,P>0 .0 5 ].两种方法测定的 Δp呈显著正相关 (r=0 .85 ,P<0 .0 1) .结论 多普勒超声心动图测压法可提供可靠的最大三尖瓣跨瓣压 ,与心导管法所测者相关显著 ,可为患者临床药物治疗及病情分析提供宝贵的血流动力学资料 ,但使用过程中需要注意影响测定准确性的技术因素以得到可靠结果 . | 曹铁生 袁丽君 段云友 S.M.沙皮洛 B.H.布朗得基 | 2000 | 第四军医大学学报2000，21，11： | 16 |
| 5 | 棉花黄萎病菌致病类型及其分子指纹分析显示文摘对20个大丽轮枝菌菌株的致病性进行了测定和RAPD指纹扩增,完成了供试菌株致病类群与其RAPD指纹组间的相关性分析。结果表明,根据20个菌株对5个棉花品种的抗感反应及其平均病情指数分为4种不同的致病类群;用10个随机引物对20个菌株进行RAPD-PCR扩增,产生92条DNA带(其中51条为多态带);用计算机进行聚类分析,20个供试菌株聚类为9个RAPD指纹组。相关性分析表明,致病类群与RAPD指纹组无明显相关性;但与部分单引物扩增的RAPD谱型有明显对应关系,如引物OPC-15随机扩增的RAPD谱型,除致病类群VG3的菌株外,其余致病类群均有对应的RAPD指纹谱带;其它引物(OPC-05,OPM-13,OPA-02,OPL-02)也有相似的结果。 | 朱有勇 王云月 Dilbag S.M. Bruce R.L. | 1998 | 中国农业科学1998，31，3： | 15 |
| 6 | 正弦波细分步进电机微步驱动器显示文摘一种新型的1024正弦波细分步进电机微步驱动器已经研制成功。用于步矩角为0.9°的二相(四相)混合式步进电机驱动时,其最高分辨率为102400微步/转.对各相绕组分别通以相位差为而幅值相同的正弦被电流,在电机内形成一个幅值不变的均匀的圆形旋转磁场。足够高的细分度以及线性功率放大器的应用,实现了步进电机恒转矩、无振动、无噪声及定调速范围的微步距运行。该微步驱动器已被成功地应用在现代精密光学天文仪器——恒星光干涉仪的自动控制系统之中. | 周尊源 S.M.欧文斯 | 1997 | 微特电机1997，25，5： | 12 |
| 7 | 江鲽在卵和卵黄囊期仔鱼发育阶段生化成分的变化显示文摘本文研究和测定了江鲽( Platichthys flesus L.)在卵和卵黄囊期仔鱼发育阶段水分、钠、钾、脂肪和蛋白质的含量变化。含水量在卵和仔鱼发育期基本保持在90—92%,在仔鱼进入初次摄食期时可降到89%左右。初孵仔鱼具一大卵黄囊,含水量高达93.3%,起“浮力器官”(buoyancy organ)的作用。钠、钾离子含量在卵受精和仔鱼出膜后波动剧烈,呈“上升—下降—再上升”式型。脂肪和蛋白质含量在卵和仔鱼早期发育和饥饿期均呈明显线性下降。同时,本文还就生化成分变化和海洋浮性鱼卵及其仔鱼的生态习性的关系作了初步探讨。 | 殷名称 S.M.哈维 J.C.A.凯克 | 1993 | 动物学报1993，39，3： | 12 |
| 8 | 多普勒测压技术在原发性肺动脉高压疗效观察中的应用显示文摘目的 :评价多普勒超声心动图观察原发性肺动脉高压 (PPH)患者疗效的应用价值。方法 :临床诊断为PPH患者 49例 ,右心导管法实时监测右房、室压及肺动脉压 2~ 3天 ;在用前列环素前、后 15分钟内进行超声多普勒检查 ,测量三尖瓣最大返流速度 ,计算右房、室间压差 (ΔP) ,并与心导管法测量结果进行相关性分析。出院后用多普勒超声心动图随访观察药物疗效。结果 :多普勒超声心动图法测定的ΔP与导管法测定结果无显著差别〔(94.7± 2 4.1)mm Hg vs.(91.6± 2 3.9) mm Hg,P>0 .0 5〕。两种方法测定的ΔP呈显著正相关 (r=0 .85 ,P<0 .0 0 0 1)。用药后 ,2 4~ 48小时后肺动脉收缩压下降〔(12 2± 18) mm Hg vs.(117± 16 ) mm Hg,P<0 .0 0 6〕。随访时间超过 330天的 18例患者 ,ΔP显著下降〔(84.1± 2 4.1) mm Hg vs.(6 2 .7± 18.2 ) mm Hg,P<0 .0 1〕。结论 :多普勒超声心动图测压法可为 PPH患者临床药物治疗及病情分析提供宝贵的血流动力学资料 ,并与心导管法有显著相关性。 | 曹铁生 袁丽君 段云友 S.M.沙皮洛 B.H.布朗得基 | 2001 | 中国超声医学杂志2001，17，2： | 11 |
| 9 | An Analytical Solution of Melting around a Moving Elliptical Heat Source显示文摘AnAnalyticalSolutionofMeltingaroundaMovingEllipticalHeatSource￥W.Z.Chen;S.M.Cheng;Z.Luo;H.Q.Zhu(HuazhongUniversityofSciencean... | W.Z. Chen S.M. Cheng Z. Luo H.Q. Zhu(Huazhong University of Science and Technology,Wuhan 430074, China) | 1994 | Journal of Thermal Science1994，3，1： | 10 |
| 10 | 比较全数字乳腺成像与荧光胶片乳腺成像:英国乳腺筛查计划和发表资料系统性回顾分析显示文摘目的(a)通过英国进行的≥50岁的女性乳腺筛查计划(每3年进行1次筛查),比较用硬拷贝图像阅读的全数字乳腺成像(FFDM)与荧光胶片乳腺成像(SFM)的表现;(b)对发表的资料与英国的数据行Meta分析。方法该研究符合英国国家健康服务中心办公室研究伦理委员会(UK National Health Service Central Office for Research Ethics Committee)的指导方针:因为是匿名资料的回顾性分析.无需告知病人。自2006年1月-2007年6月,筛查中心对8478名伦敦人进行了FFDM筛查,对31720人进行了SFM筛查。 | S. Vinnicombe S.M. Pinto Pereira V.A. McCormack S. Shiel N. Perry I.M. Dos Santos Silva. 郑梅竹(译) 葛夕洪(校) | 2009 | 国际医学放射学杂志2009，32，4： | 10 |
| 11 | Sequence assembly using next generation sequencing data —challenges and solutions显示文摘Sequence assembling is an important step for bioinformatics study.With the help of next generation sequencing(NGS)technology,high throughput DNA fragment(reads)can be randomly sampled from DNA or RNA molecular sequence.However,as the positions of reads being sampled are unknown,assembling process is required for combining overlapped reads to reconstruct the original DNA or RNA sequence.Compared with traditional Sanger sequencing methods,although the throughput of NGS reads increases,the read length is shorter and the error rate is higher.It introduces several problems in assembling.Moreover,paired-end reads instead of single-end reads can be sampled which contain more information.The existing assemblers cannot fully utilize this information and fails to assemble longer contigs.In this article,we will revisit the major problems of assembling NGS reads on genomic,transcriptomic,metagenomic and metatranscriptomic data.We will also describe our IDBA package for solving these problems.IDBA package has adopted several novel ideas in assembling,including using multiple k,local assembling and progressive depth removal.Compared with existence assemblers,IDBA has better performance on many simulated and real sequencing datasets. | CHIN Francis Y.L. LEUNG Henry C.M. YIU S.M. | 2014 | Science China(Life Sciences)2014，57，11： | 8 |
| 12 | Effects of CO_2 content on the activity and stability of nickel catalyst supported on mesoporous nanocrystalline zirconia显示文摘The effects of carbon dioxide content on the catalytic performance and coke formation of nickel catalyst sup- ported on mesoporous nanocrystalline zirconia with high surface area and pure tetragonal crystalline phase were investigated in methane reforming with carbon dioxide. The samples were characterized by XRD, BET, TPR, TPO, TPH, TEM, and SEM techniques. The catalyst prepared showed high surface area and a mesoporous structure with a narrow pore size distribution. The obtained results revealed that the increase in CO2 content increased the methane conversion and stability of the catalyst and significantly reduced the coke deposition. The TPH analysis showed that several species of carbon with different reactivities toward hydrogenation were deposited on the spent catalysts employed under different CO2 contents. | M. Rezaei S.M. Alavi S. Sahebdelfar Zi-Feng Yan | 2008 | Journal of Natural Gas Chemistry2008，17，3： | 5 |
| 13 | IVF或ICSI周期卵巢过度刺激获取大量卵子并不会导致妊娠率降低显示文摘Objective: To investigate the possible negative effects of a strong ovarian response on oocyte quality.Design: Retrospective study.Setting: Tertiary academic center.Patient(s): A total of 1, 894 women (IVF, n = 1, 544; ICSI, n = 350) who underwent their first ovarian stimulation cycle during the period 1995- 2002.Intervention(s): Standardized controlled ovarian stimulation with urinary FSH or recombinant FSH after pituitary down- regulation, followed by IVF/intracytoplasmic sperm injection (ICSI) and ET.Main Outcome Measure(s): Fertilization rate, fraction of high- quality embryos, and implantation rate.Result(s): Using multivariate logistic regression, we analyzed the effect, expressed as an odds ratio (OR), of the number of oocytes obtained (i.e., ovarian response) on the outcome measures.No effect of the response on the ongoing implantation rate or fraction of high- quality embryos was observed.Both in IVF (OR = 0.81, 95% confidence interval [CI] 0.75- 0.87) and in ICSI (OR = 0.88, 95% CI 0.76- 1.00), a negative effect of increasing ovarian response was seen on the fertilization rate per oocyte obtained.However, no negative effect was observed on the fertilization rate per oocyte injected in ICSI (OR = 1.00, 95% CI 0.87- 1.14).The fraction of immature oocytes rises from 3.9% , in women with ≤ 3 oocytes, to 26% in women with > 20 oocytes.Conclusion(s): Oocytes from high responders contain a greater fraction of immature oocytes, but pregnancy outcome is not impaired. | Kok J.D. Looman C.W.N. Weima S.M. Te Velde E.R. 朱亮 | 2006 | 世界核心医学期刊文摘(妇产科学分册)2006，2，9： | 5 |
| 14 | Grain Size Effect on the Martensite Formation in a High-Manganese TWIP Steel by the Rietveld Method显示文摘The aim of the present work was to study the effect of austenite grain size (AGS) on the martensite formation in a high-manganese twinning-induced plasticity (TWIP) steel. The results of a quantitative microstructural characterization of the steel by the whole X-ray pattern fitting Rietveld software, materials analysis using diffraction (MAUD), indicated that the volume fraction of α bcc-martensite increases with increasing AGS. However, the value of the stacking fault probability (P sf ) does not show a large variation for samples with different values of AGS under water-quenching conditions. | G. Dini A. Najafizadeh S.M. Monir-Vaghefi R. Ueji | 2010 | Journal of Materials Science & Technology2010，26，2： | 5 |
| 15 | 从社会的观点看自然化的科学哲学显示文摘一、导论 最近,对科学哲学自然化的讨论不怎么关心科学实践的社会本质,它们所注重的是,利用认知科学的成果来解释科学。我要证明,这种探讨有缺陷。这是因为,第一,它们采用了我所谓的认知个体主义,第二,科学实践的社会性是不可化简的。认知个体主义即这样一个命题:自主的认知个体的说明,能对所有的认知活动作出圆满的解释。认知个体主义与方法论个体主义有着一定的联系,因为认知个体主义者把个体作为他们的解释理论的分析单位,不过认知个体主义是一种更为狭隘的主张,它与社会科学哲学家所说的心理主义更为相似。按照它的观点,可以用根据自主的个体内在的心理机制所能描述的东西来定义什么是认知的。相对于这种观点,我将提出一种有关科学知识的社会本质的模型,该模型选出了几种理解“社会的”这个词的方式,任何一个较为完备的有关科学实践的模型中肯定都会有这几种方式。我的主张吸收了科学社会学的研究成果,但相对于伍尔伽和拉图尔(1980)、拉图尔本人(1987)以及柯林斯(1985)所提出的“构造主义的” | S.M.唐斯 王政挺 | 1994 | 世界哲学1994，，4： | 5 |
| 16 | 地膜覆盖对滴灌甜菜生育进程及产量的影响显示文摘【目的】分析地膜覆盖对滴灌甜菜产量和品质的调控效应,为干旱区滴灌甜菜高产优质生产提供理论依据。【方法】以新甜12号为研究对象,进行破坏性取样,调查露播和覆膜滴灌甜菜干物质积累、根冠比、产量以及块根含糖量指标。【结果】与露播滴灌甜菜相比,地膜覆盖的增温效应使滴灌甜菜提前10 d结束叶丛快速生长期,LAI峰值提高1.84,在延长块根糖分增长期的同时,形成适宜的根冠比。膜下滴灌甜菜单产和含糖量分别较露地滴灌甜菜提高0%和17%。【结论】与露播滴灌相比,覆膜可显著增加滴灌甜菜块根含糖量,但是对甜菜产量无明显影响。 | 樊华 Koibakov S.M. 帕尼古丽 Nurabayev Daulen 林凤 马富裕 | 2014 | 新疆农业科学2014，51，4： | 5 |
| 17 | A comprehensive investigation of loading variance influence on fuel consumption and gas emissions in mine haulage operation显示文摘The data collected from haul truck payload management systems at various surface mines show that the payload variance is significant and must be considered in analysing the mine productivity, diesel energy consumption, greenhouse gas emissions and associated costs. The aim of this study is to determine the energy and cost saving opportunities for truck haulage operations associated with the payload variance in surface mines. The results indicate that there is a non-linear relationship between the payload variance and the fuel consumption, greenhouse gas emissions and associated costs. A correlation model, which is independent of haul road conditions, has been developed between the payload variance and the cost saving using the data from an Australian surface coal mine. The results of analysis for this particular mine show that a significant saving of fuel and greenhouse gas emissions costs is possible if the standard deviation of payload is reduced from the maximum to minimum value. | Soofastaei A. Aminossadati S.M. Kizil M.S. Knights P. | 2016 | International Journal of Mining Science and Technology2016，26，6： | 4 |
| 18 | 一种新型高屈服强度的转变和孪晶诱发塑性效应的多元β钛合金显示文摘在某种商业化合金的基础上,利用d电子方法设计了一种新型的多元β钛合金Ti-3Al-5Mo-7V-3Cr(Ti-3573)。所设计的合金具有优异的力学性能,如750 MPa优异的屈服强度,1,800 MPa高的应变硬化率(SHR)及19%的均匀延伸率。显微组织测定表明,转变和孪晶诱发塑性是拉伸性能提高的主要因素。结果表明:通过精确控制合金化条件,就可能用固溶法提高屈服强度,同时保持应变硬化率和足够高的延性。 | S.萨德堡 S.M.阿巴西 M.莫拉卡巴提 A.基思科 L.P.卡亚雷宁 D.A.波特 王镐 | 2018 | 中国钛业2018，，2： | 4 |
| 19 | Clear felling and burning effects on soil nitrogen transforming bacteria and actinomycetes population in Chittagong University campus, Bangladesh显示文摘The effect of forests clear felling and associated burning on the population of soil nitrogen transforming bacteria and actinomycetes are reported at three pair sites of Chittagong University campus, Bangladesh in monsoon tropical climate. Clear felled area or burnt site and 15-21 year mixed plantation of native and exotic species, situated side by side on low hill having Typic Dystrochrepts soil was represented at each pair site. At all the three pair sites, clear felled area or burnt site showed very significantly (p≤0.001) lower population of actinomycetes, Rhizobium, Nitrosomonas, Nitrobacter and ammonifying as well as denitrifying bacteria compared to their adjacent mixed plantation. From environmental consideration, this finding has implication in managing natural ecosystem. | S.M. Sirajul Haque Rahima Ferdoshi Sohag Miah M. Nural Anwar | 2012 | Journal of Forestry Research2012，23，1： | 4 |
| 20 | 油藏环境石油烃厌氧生物降解产甲烷途径与生物标志物显示文摘油藏环境石油烃厌氧生物降解产甲烷过程是生物地球化学的基础问题之一;同时,由于油藏环境微生物在微生物采油、生物腐蚀及生物治理等方面具有重要的应用价值,已经受到国际同行高度关注.近10多年来,随着分子生物学技术、特别是新一代测序技术的发展,为深入认识这一特殊地质环境中烃厌氧生物降解过程提供了新的研究手段.本文以油藏环境石油烃厌氧生物降解途径和生物标志物为重点,综述了石油烃厌氧降解产甲烷机理方面的最新成果,以及宏基因组测序分析手段在油藏相关样品方面的应用及研究进展,讨论了油藏残余油生物气化开采的微生物基础,提出了该领域进一步研究的方向. | 刘一凡 周蕾 寿利斌 Mbadinga S.M. 刘金峰 杨世忠 牟伯中 | 2018 | 地球科学2018，43，A01： | 4 |
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