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| 1 | Potential role of metabolomics in diagnosis and surveillance of gastric cancer显示文摘Gastric cancer is one of the deadliest cancers worldwide, and is especially prevalent in Asian countries. With such high morbidity and mortality, early diagnosis is essential to achieving curative intent treatment and long term survival. Metabolomics is a new field of study that analyzes metabolites from biofluids and tissue samples. While metabolomics is still in its infancy, there are numerous potential applications in oncology, specifically early diagnosis. Only a few studies in the literature have examined metabolomics' role in gastric cancer. Various fatty acid, carbohydrate, nucleic acid, and amino acid metabolites have been identified that distinguish gastric cancer from normal tissue and benign gastric disease. However, findings from these few studies are at times conflicting. Most studies demonstrate some relationship of cancer cells to the Warburg Effect, in that glycolysis predominates with conversion of pyruvate to lactate. This is one of the most consistent findings across the literature. There is less consistency in metabolomic signature with respect to nucleic acids, lipids and amino acids. In spite of this, metabolomics holds some promise for cancer surveillance but further studies are necessary to achieve consistency and validation before it can be widely employed as a clinical tool. | Angela W Chan Richdeep S Gill Daniel Schiller Michael B Sawyer | 2014 | World Journal of Gastroenterology2014,20,36: | 9 |
| 2 | 美国高等医学考试体制及借鉴显示文摘一、美国医学教育体制及相匹配的考试体制以1992年资料为准,美国医学教育分为三阶段(个别情况除外)。 1.在校医学教育(Undergraduate MedicalEducation)。美国大学生获学士学位以后,申请报名参加全美医学院校入学考试(Medical College Admis-sion Test)。考试以后,由各医学院自行决定录取。进入医学院学习,为期四年,前两年为基础医学教育,后两年为临床医学教育。 1992年,报名36800人,录取17027新生,录取率为46%,其中88%已获学士学位,7.3%已获硕士或博士学位。女生占40%。 1992年全美共126所医学院,总计在校生为65539名,当年毕业生为15466人,当年淘汰率1.3%。与之相匹配的考试制度:在校学生要参加两方面考试,一方面是各学科课程考试及实习考试。 | 孙宝志 Norcini J Sawyer W | 1993 | 中国高等医学教育1993,,6: | 7 |
| 3 | Improved wear resistance in aluminaPTFE nanocomposites with irregular shaped nanoparticles显示文摘 | Burris D L Sawyer W G | 2006 | Wear2006,260,91: | 1 |
| 4 | Toward a theory of organizational creativity显示文摘 | Woodman R W Sawyer J E Griffin R W | 1993 | Academy of Management Review1993,,18: | 1 |
| 5 | Improved wear resistance in alumina-PTFE nanocomposites with irregular shaped nanoparticles 显示文摘 | Burris D Sawyer W | 2006 | Wear2006,260,: | 1 |
| 6 | Toward atheory of organizational creativity 显示文摘 | Woodman R W Sawyer J E Griffin R W | 1993 | Academy ofManagement Review1993,,18: | 1 |
| 7 | Multifunetionality of sin- gle-walled carbon nanotube- polytetra? uoroethylene nano- composites 显示文摘 | Vail J R Burris D L Sawyer W G | 2009 | Wear2009,267,14: | 1 |
| 8 | Toward a theory of organizational creativity显示文摘 | WOODMAN R W SAWYER J E GRIFFIN R W | 1993 | Academy of Man- agement Review1993,18,: | 1 |
| 9 | Endpoint estimates for commutators of singular integrals on spaces of homogeneous type显示文摘 | CHEN W G SAWYER E | 2003 | J Math Anal Appl2003,282,: | 1 |
| 10 | Polymorphonuclear neutrophils: an effeetive antimierobial force 显示文摘 | SAWYER D W ODNOVITZ G R MANDELL G L | 1989 | Rev Infect1989,11,15: | 1 |
| 11 | Effects of first-line use of nucleo- side analogues, efavirenz, and ritonavir-boosted protease inhibi- tors on lipid levels显示文摘 | Hill A Sawyer W Gazzard B | 2009 | HIV Clin Trials2009,10,1: | 1 |
| 12 | Nickel-copper occurrences in the belleterre-Angliers belt of the Pontiac subprovince and the use of Cu-Pd rations in interpreting platinum group element distributions显示文摘 | Barnes S J Couture J F Sawyer E W Bouchaib C | | 0,,: | 1 |
| 13 | Toward a theory of organizational creativity显示文摘 | Woodman R W Sawyer j E and Griffin R W | 1993 | Academy of Management Review1993,18,: | 1 |
| 14 | Toward a theory of or- ganizational creativity 显示文摘 | Woodman R W Sawyer J E Griffin R W | 1993 | Academy Of Management Review1993,18,2: | 1 |
| 15 | Toward a theory of organizational creativity 显示文摘 | Woodman R W Sawyer J E Griffin R W | 1993 | Academy of Management Review1993,18,: | 1 |
| 16 | Effect of stitching on the strength of bonded composite single lap joints 显示文摘 | SAWYER J W | 1985 | AIAAJ1985,23,11: | 1 |
| 17 | Toward a theory of organizational creativity显示文摘 | Woodman R H Sawyer J E Griffin R W | | 0,,02: | 1 |
| 18 | Standards for biodiversity: A proposal based on biodiversity standards for fore plantations 显示文摘 | Spellerberg I F Sawyer J W D | 1996 | Biodiversity and Conservation1996,5,: | 1 |
| 19 | Behavior of concentrated polymer solutions under periodic stresses显示文摘 | John D Ferry Sawyer W M Ashworth J N | 1947 | J Polym Sci1947,2,: | 1 |
| 20 | Toward a Theory of Organizational Creativity显示文摘 | Woodman R W Sawyer J E Griffin R W | | 0,,02: | 1 |