维普期刊资源整合服务平台（V6.5）

150篇 您的检索式：作者名="SCRUGGS"

选中清除导出查看参考文献查看引证文献引用追踪共8页首页上一页第1页下一页末页 /8 跳转

	题名	作者	年代	出处	被引量
1	Calcium signaling and T-type calcium channels in cancer cell cycling显示文摘Regulation of intracellular calcium is an important signaling mechanism for cell proliferation in both normal and cancerous cells. In normal epithelial cells, free calcium concentration is essential for cells to enter and accomplish the S phase and the M phase of the cell cycle. In contrast, cancerous cells can pass these phases of the cell cycle with much lower cytoplasmic free calcium concentrations, indicating an alternative mechanism has developed for fulfilling the intracellular calcium requirement for an increased rate of DNA synthesis and mitosis of fast replicating cancerous cells. The detailed mechanism underlying the altered calcium loading pathway remains unclear; however, there is a growing body of evidence that suggests the T-type Ca2+ channel is abnormally expressed in cancerous cells and that blockade of these channels may reduce cell proliferation in addition to inducing apoptosis. Recent studies also show that the expression of T-type Ca2+ channels in breast cancer cells is proliferation state dependent, i.e. the channels are expressed at higher levels during the fast-replication period, and once the cells are in a non-proliferation state, expression of this channel isminimal. Therefore, selectively blocking calcium entry into cancerous cells may be a valuable approach for preventing tumor growth. Since T-type Ca2+ channels are not expressed in epithelial cells, selective T-type Ca2+ channel blockers may be useful in the treatment of certain types of cancers.	James T Taylor Xiang-Bin Zeng Jonathan E Pottle Kevin Lee Alun R Wang Stephenie G Yi lennifer A S Scruggs Suresh S Sikka Ming Li	2008	World Journal of Gastroenterology2008，14，32：	12
2	FRVT 2006 and ICE 2006 large-scale ex- perimental results显示文摘	Phillips P J Scruggs T O'Toole A Flynn P J Bowyer K W Sehott C Sharpe M	2010	IEEE Transactions on Pattern Analysis and Machine Intelligence2010，32，5：	1
3	Political and economic inequality and the environment显示文摘	Lyle A Scruggs	1998	Ecological Economics1998，，3：	1
4	Infiltration on mountain slopes : a comparison of three environments 显示文摘	Harden C P Scruggs P D	2003	Geomorphology2003，55，：	1
5	Dynamic deformation behavior of tungsten-'ber/metallic} glass matrix com- posites 显示文摘	CONNER R D DANDLIKER R B SCRUGGS V	2000	International Journal of Impact Engineering2000，24，：	1
6	FRVT 2006 and ICE 2006 large-scale experimental results 显示文摘	Phillips PJ Scruggs WT O' Toole AJ	2010	IEEE Tram on Pattern Analysis and Machine InteUigence2010，32，5：	1
7	Long-term follow-up of patients of intrahepatic malignancies treated with iodine-125 brachy-therapy 显示文摘	Nag S DeHaan M Scruggs G	2006	Radiat Oncol Biol Phys2006，64，3：	1
8	Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts显示文摘	HUANG S K SCRUGGS A M DONAGHY J	2013	Cell Death Dis2013，，4：	1
9	Dynamic deformation behavior of tungsten-fiber/metallic–glass matrix composites显示文摘	R.D Conner R.B Dandliker V Scruggs W.L Johnson	2000	International Journal of Impact Engineering2000，，5：	1
10	Mechanisms of zidovudineinduced mitochondrial toxicity and myopathy显示文摘	Scruggs ER Dirks Naylor AJ	2008	Pharmacology2008，82，2：	1
11	FRVT 2006 and ICE 2006 large-scale experimental results显示文摘	Phillips P J Scruggs W T O'Toole A J	2010	IEEE Transactions on Pattern Analysis and Machine Intelligence2010，32，5：	1
12	An MRM-based workflow for quantifying cardiac mitochondrial protein phosphorylation in murine and human tissue显示文摘	Lam MPY Scruggs SB Kim TY	2012	J Proteomics2012，75，：	1
13	Political and Economics Inequality and the Environment 显示文摘	Scruggs L A	1998	Ecological Economics1998，，26：	1
14	Frvt 2006 and ice 2006 large-scale experimental results 显示文摘	Phillips P J Scruggs W T O'Toole A J	2010	IEEE Transactions on Pattern Analysis and Machine Intelligence2010，32，5：	1
15	Long-term follow-up of patients of intrahepatic malignancies treated with iodine-125 brachytherapy 显示文摘	Nag S DeHaan M Scruggs G	2006	Int J Radiat Oncol Biol Phys2006，64，：	1
16	Long-term follow-up ofpatients of intrahepatic malignancies treated with iodine-125 brachytherapy显示文摘	Nag S DeHaan M Scruggs G	2006	Int J Radiat Oncol Biol Phys2006，64，3：	1
17	Long-term follow-up of patients of intrahepatic malignancies treated with iodine- 125 brachytherapy显示文摘	Nag S Dehaan M Scruggs G	2006	Int J Radiat Oncol Biol Phys2006，64，：	1
18	Political and Economic Inequality and theEnvironment 显示文摘	Scruggs L A	1998	Ecological Economics1998，26，：	1
19	The Two Endings of The French Lieutenant' s Woman显示文摘	Scruggs Charles	1985	Modern Fiction Studies1985，，1：	1
20	Carcinoma of the mobile tongue:incidence of cervical metastasis in early lesions related to method of primary treatment显示文摘	Bradfield JS Scruggs RP	1983	Laryngoscope1983，93，10：	1

返回顶部每页显示：

共8页首页上一页第1页下一页末页 /8 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示