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| 1 | Management of hepatocellular carcinoma with portal vein tumor thrombosis: Review and update at 2016显示文摘Portal vein tumor thrombosis(PVTT) is a common phenomenon in hepatocellular carcinoma(HCC). Compared to HCC without PVTT, HCC with PVTT is characterized by an aggressive disease course, worse hepatic function, a higher chance of complications related to portal hypertension and poorer tolerance to treatment. Conventionally, HCC with PVTT is grouped together with metastatic HCC during the planning of its management, and most patients are offered palliative treatment with sorafenib or other systemic agents. As a result, most data on the management of HCC with PVTT comes from subgroup analyses or retrospective series. In the past few years, there have been several updates on management of HCC with PVTT. First, it is evident that HCC with PVTT consists of heterogeneous subgroups with different prognoses. Different classifications have been proposed to stage the degree of portal vein invasion/thrombosis, suggesting that different treatment modalities may be individualized to patients with different risks. Second, more studies indicate that more aggressive treatment, including surgical resection or locoregional treatment, may benefit select HCC patients with PVTT. In this review, we aim to discussthe recent conceptual changes and summarize the data on the management of HCC with PVTT. | Stephen L Chan Charing CN Chong Anthony WH Chan Darren MC Poon Kenneth SH Chok | 2016 | World Journal of Gastroenterology2016，22，32： | 44 |
| 2 | The Responsivity of the Bacteriorhodopsin Langmuir-Blodgett Film Intermittent Light显示文摘TheResponsivityoftheBacteriorhodopsinLangmuir-BlodgettFilmIntermittentLight￥GuangYuWANG;JianHuaYANG;ZhiGuangZHANG;ShuHuangLIN... | Wang, GY Yang, JH Zhang, ZG Lin, SH Lu, T Li, BF Jiang, L | 1996 | Chinese Chemical Letters1996，7，12： | 12 |
| 3 | Induction of mucosal and systemic immune response by single-dose oral immunization with biodegradable microparticles containing DNA encoding HBsAg显示文摘 | He XW Wang F Jiang L Li J Liu SK Xiao ZY Jin XQ Zhang YN He Y Li K Guo YJ Sun SH | 2005 | 第二军医大学学报2005，26，10： | 5 |
| 4 | 限制卡路里摄入可抑制大鼠促进动脉衰老的炎症反应,保持年轻的表型显示文摘老化呈指数性增加典型心血管病的发病率和死亡率,这主要是由于动脉壁内分子、细胞和组织水平的动脉促炎变化。动物实验中,大鼠的卡路里限制(calorie restriction,CR)改善了动脉功能并延长了健康跨度和寿命。然而,CR如何影响大鼠动脉壁内分子,细胞和组织表型促炎变化仍有待阐明。该文选取随意喂食的344只年轻(6个月大)和老(24个月大)的Fischer大鼠,获取主动脉;另外选取1组在1个月大时开始只维持40%CR。 | 刘青 叶鹏 Wang MY Zhang L Zhu WQ Zhang J Kim SH Wang YS Ni L Telljohann R Monticone RE McGraw K Liu LJ Rafael de Cabo Lakatta EG | 2018 | 中华高血压杂志2018，26，11： | 3 |
| 5 | Parental cigarette smoking and the risk of spontaneous abortion显示文摘 | Windham GC Swan SH Fenster L | 1992 | Am J Epidemiol1992，135，： | 2 |
| 6 | Inhibitory actions of MCI-154 on guinea-pig femoral artery and vein preparations显示文摘 | Suh SH Chen G Xue L Zhang G Yamamoto Y Suzuki H | 1992 | Eur J Pharmacol1992，219，3： | 1 |
| 7 | Notch signaling auguments T cell responsiveness by enhancing CD25 expression显示文摘 | Adler SH Chiffoleau E Xu L | 2003 | J Immunol2003，171，6： | 1 |
| 8 | Paclitaxel induces programmed cell death in MDA-MB- 486 human breast cander cells显示文摘 | McCloskey DE Kaufmann SH Prestigiacomo L J | 1996 | Clin Cancer Res1996，2，5： | 1 |
| 9 | The 1998 enterovims 71 outbreak in Taiwan:pathogenesis and management显示文摘 | Lin T Chang L Hsis SH | 2002 | Clin infect Dis2002，34，2： | 1 |
| 10 | Pericentric inversion 9-incidence and clinical significance 显示文摘 | eo SH Tan M Knight L | 1995 | Ann Acad Med Singapore1995，24，2： | 1 |
| 11 | QoS-Aware middleware for Web services composition 显示文摘 | Zeng L Z Benatalla Sh B Dumas M | 2004 | IEEE Transactions on Software Engineering2004，30，5： | 1 |
| 12 | Experiment study on friction drive显示文摘 | WANG G M MA L SH YAO ZH Q | 2004 | SPIE2004，5495，： | 1 |
| 13 | Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells显示文摘 | Lee SH Lumelsky N Studer L | 2000 | Nature Biotechnology2000，18，5： | 1 |
| 14 | Surface Tension of Trifluoroiodomethane (CF3I)显示文摘 | Duan Y Y Shi L Zhu M Sh | 1999 | Fluid Phase Equilibria1999，154，1： | 1 |
| 15 | Gene expression in colorectal cancer显示文摘 | Birkenkamp-Demtroder K Christensen L L Olesen SH | 2002 | Cancer Res2002，62，： | 1 |
| 16 | FoxM1 expression is significantly associated with cisplatin-based chemotherapy resistance and poor prognosis in advanced non-small cell lung cancer patients显示文摘 | Wang Y Wen L Zhao SH | 2013 | Lung Cancer2013，79，2： | 1 |
| 17 | Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma- H2 AX and suppresses DNA double strand break repair 显示文摘 | Moon SH Lin L Zhang X | 2010 | J Bioi Chern2010，285，12： | 1 |
| 18 | 显示文摘 | Simpson SH Gamble JM Mereu L etal Effect of aspirin does on mortality and cardiovascular events in people with diabetes:a meta- analysis | 2011 | J Gen Inter Med2011，26，11： | 1 |
| 19 | Oxidative stress: apoptosis in neuronal injury显示文摘 | Lob KP Huang SH De Silva R et a l | 2006 | Curr Alzheimer Res2006，3，： | 1 |
| 20 | Ultra-short optical pulse source based on phase and intensity hybrid modulation 显示文摘 | ZHOU H B LOU C Y PAN Sh L | 2007 | Journal of Tsinghua University2007，48，4： | 1 |
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