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| 1 | Cytokines,cytokine gene polymorphisms and Helicobacter pylori infection:Friend or foe?显示文摘Helicobacter pylori(H.pylori)is a flagellated,spiralshaped,microaerophilic Gram-negative bacillus that colonises the gastric mucosa of more than 50%of the human population.Infection is a risk factor for gastritis,ulcer disease and stomach cancer.Immunity against H.pylori is mainly related to Th1/Th17 skewing,and the activation of regulatory T cells is the main strategy used to limit inflammatory responses,which can result in the pathogen persistence and can lead to chronic gastrointestinal diseases,including cancer.Furthermore,host genetic factors that affect cytokines may determine differences in the susceptibility to many diseases.In this review,we present the cytokine profiles and the main cytokine gene polymorphisms associated with resistance/susceptibility to H.pylori and discuss how such polymorphisms may influence infection/disease outcomes. | Camila A Figueiredo Cintia Rodrigues Marques Ryan dos Santos Costa Hugo Bernardino F da Silva Neuza M Alcantara-Neves | 2014 | World Journal of Gastroenterology2014，20，18： | 11 |
| 2 | High prevalence of vitamin A deficiency in Crohn's disease patients according to serum retinol levels and the relative dose-response test显示文摘AIM:To assess the vitamin A status of patients with Crohn's disease(CD) by evaluating serum retinol levels and the relative dose response(RDR) test(liver retinol stores).METHODS:Vitamin A nutritional status was measured by serum retinol obtained by high performance liquid chromatography and the RDR test for evaluation of the hepatic stores.Body composition was performed by densitometry by dual-energy X-ray absorptiometry.Vitamin A dietary intake was assessed from a semiquantitative food frequency questionnaire.RESULTS:This study included 38 CD patients and 33 controls.Low serum retinol concentrations were detected in 29% of CD patients vs 15% in controls(P < 0.005).The RDR test was positive in 37% of CD patients vs 12% in controls,which indicated inadequate hepatic vitamin A stores(P < 0.005).Individuals with hypovitaminosis A had lower BMI and body fat compared with those without this deficiency.There was no association between vitamin A deficiency and its dietary intake,ileal location,presence of disease activity and prior bowel resections.CONCLUSION:Patients with CD have higher prevalence of vitamin A deficiency,as assessed by two independent methods. | Márcia Soares-Mota Tianny A Silva Luanda M Gomes Marco AS Pinto Laura MC Mendon?a Maria Lúcia F Farias Tiago Nunes Andrea Ramalho Cyrla Zaltman | 2015 | World Journal of Gastroenterology2015，21，5： | 4 |
| 3 | 定期运动有助于改善高血压患者蛋白质稳态、炎症和血管活性显示文摘体育锻炼是一种公认的非药物控制血压的策略,除了降低血压外,运动还能对高血压患者的炎症特征、自主功能、内皮功能和抗氧化状态产生积极的影响。但其对高血压患者的蛋白质稳态的影响尚不清楚。已有动物研究表明,运动训练干预可以改善蛋白质质量控制机制,但在动物模型中报告的积极作用仍有待于在人类身上得到证实。本研究旨在根据报告的运动习惯,评估患高血压成年人的蛋白质稳态,生活质量以及炎症、氧化应激和血管活性生物标记物状态。 | Teixeira M Gouveia M Duarte A Ferreira M Simões MI Conceição M Silva G Magalhães S Ferreira R Nunes A Vieira SI Ribeiro F 周卫(译) 叶鹏(审校) | 2020 | 中华高血压杂志2020，28，12： | 2 |
| 4 | Risk Factors for Posterior Compared to Anterior Ischemic Stroke: An Observational Study of the Registry of the Canadian Stroke Network显示文摘 | Subramanian G Silva J Silver F L Fang J Kapral M K Oczkowski W Gould L O’donnell M J | 2009 | Neuroepidemiology2009，，1： | 2 |
| 5 | NEW TOXOPLASMA GONDII GENOTYPES ISOLATED FROM FREE-RANGE CHICKENS FROM THE FERNANDO DE NORONHA, BRAZIL: UNEXPECTED FINDINGS显示文摘 | Dubey J P Rajendran C Costa D G C Ferreira L R Kwok O C H Qu D Su C Marvulo M F V Alves L C Mota R A Silva J C R | 2010 | The Journal of Parasitology2010，，4： | 2 |
| 6 | The role of major histocompatibility complex alleles in the susceptibility of Brazi-lian patients to develop the myogenic type of Graves' orbitopathy显示文摘 | Akaishi P M Cruz A A Silva F L | 2008 | Thyroid2008，18，4： | 1 |
| 7 | Aluminium Doped Zinc Oxide Films: Formation Process and Optical Properties 显示文摘 | Silva R F Zaniquelli M E D | 1999 | Jounral of Non-crystalline Soliders1999，247，： | 1 |
| 8 | Decreased sperm motility in rats orally exposed to single or mixed pesticides 显示文摘 | Perobelli J E Martinez M F da Silva Franchi C A | 2010 | Journal of Toxicology and Environment Health A2010，73，1314： | 1 |
| 9 | Physiological responses to salt stress in young umbu plants显示文摘 | Da Silva E C Nogueira R J M C de Arajo F P etal | 2008 | Environmental and Experimental Botany2008，63，3： | 1 |
| 10 | Tribological behaviour of Si3N4-BN ceramic materials for dry sliding applications显示文摘 | Carrapichano J M Comes J R Silva R F | 2002 | Wear2002，253，： | 1 |
| 11 | Dielectric and structural studies of a SiO2-Li2O-Nb2O5 glass and glass-ceramic prepared by the sol-gel method显示文摘 | GRACA J M P F FERREIRA da SILVA M G VALENTE M A | 2005 | Journal of Non-crystalline Solids2005，351，33： | 1 |
| 12 | Application of chronological load modeling in composite reliability worth evaluation显示文摘 | Mello J C O Pereira M V F Leite da Silva A M | 1997 | Electric Power Systems Research1997，，40： | 1 |
| 13 | Anionic flotation of railings of manganese ore 显示文摘 | Lima R M F Vasconcelos J A da Silva G R | 2008 | Rem-revista Escolade Minas2008，61，3： | 1 |
| 14 | Sealing ef- fectiveness of etch-and-rinse vs self-etching adhesives af- ter water aging: influence of acid etching and NaOC1 dentin pretreatment显示文摘 | Monticelli F Toledano M Simoes Silva A | 2008 | Adhes Dent2008，10，： | 1 |
| 15 | Novel scorpionate and pyrazole dioxovanadium complexes,catalysts for carboxylation and peroxidative oxidation of alkanes显示文摘 | Silva T F S Luzyanin K V Kirillova M V | 2010 | Adv Synth Catal2010，352，： | 1 |
| 16 | Different ni- trogen sources affect biomass partitioning and quality of potato production in a hydroponic system 显示文摘 | Silva J G Franqa M G C Gomide F T F | 2013 | American Journal of Potato Research2013，90，2： | 1 |
| 17 | Parametric Study of Adhesive Joints with Composites 显示文摘 | NETO J A B P CAMPILHO R D S G DA SILVA L F M | 2012 | International Journal of Adhesion and Adhesives2012，，： | 1 |
| 18 | Revisiting the fundamental of single point incremental forming by means of mem- brane analysis显示文摘 | Silva M B Skjoedt M Martins P A F | 2008 | International Journal of Machine Toll & Manufacture2008，48，1： | 1 |
| 19 | Analytical models of adhesively bonded joints-Part I:literature survey显示文摘 | da Silva L F M das Neves P J C Adams R D | 2009 | International Journal of Adhesion and Adhesives2009，29，3： | 1 |
| 20 | Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid 显示文摘 | Silva R F Rodrigues C M Brites D | 2001 | J Hepatol2001，34，3： | 1 |
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