|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Diagnostic value of drain amylase for detecting intrathoracic leakage after esophagectomy显示文摘AIM:To investigate the value of elevated drain amylase concentrations for detecting anastomotic leakage(AL) after minimally invasive Ivor-Lewis esophagectomy(MIILE).METHODS:This was a retrospective analysis of prospectively collected data in two hospitals in the Netherlands. Consecutive patients undergoing MI-ILE were included. A Jackson-Pratt drain next to the dorsal side of the anastomosis and bilateral chest drains were placed at the end of the thoracoscopic procedure. Amylase levels in drain fluid were determined in all patients during at least the first four postoperative days. Contrast computed tomography scans and/or endoscopic imaging were performed in cases of a clinically suspected AL. Anastomotic leakage was defined as any sign of leakage of the esophago-gastric anastomosis on endoscopy,re-operation,radiographic investigations,post mortal examination or when gastro-intestinal contents were found in drain fluid. Receiver operator characteristic curves were used to determine the cut-off values. Sensitivity,specificity,positive predictive value,negative predictive value,risk ratio and overall test accuracy were calculated for elevated drain amylase concentrations.RESULTS:A t o t a l o f 8 9 p a t ie n t s w e re in c lu d e d between March 2013 and August 2014. No differences in group characteristics were observed between patients with and without AL,except for age. Patients with AL were older than were patients without AL(P = 0.01). One patient(1.1%) without AL died within 30 d after surgery due to pneumonia and acute respiratory distress syndrome. Anastomotic leakage that required any intervention occurred in 15 patients(16.9%). Patients with proven anastomotic leakage had higher drain amylase levels than patients without anastomotic leakage [median 384 IU/L(IQR 34-6263) vs median 37 IU/L(IQR 26-66),P = 0.003]. Optimal cut-off values on postoperative days 1,2,and 3 were 350 IU/L,200 IU/L and 160 IU/L,respectively. An elevated amylase level was found in 9 of the 15 patients with AL. Five of these 9 patients had early elevations of their amylase levels,with a median of 2 d(IQR 2-5) before signs and symptoms occurred.CONCLUSION:Measurement of drain amylase levels is an inexpensive and easy tool that may be used to screen for anastomotic leakage soon after MI-ILE. However,clinical validation of this marker is necessary. | Gijs HK Berkelmans Ewout A Kouwenhoven Boudewijn JJ Smeets Teus J Weijs Luis C Silva Corten Marc J van Det Grard AP Nieuwenhuijzen Misha DP Luyer | 2015 | World Journal of Gastroenterology2015，21，30： | 3 |
| 2 | Biomarkers of satiation and satiety 显示文摘 | DE G C BLOM W A SMEETS P A | 2004 | Am J Clin Nutr2004，79，6： | 1 |
| 3 | Synthesis,X-ray crystal structure and magenetism of (C2H5OH)2-a second example of a ferromagnetically coupled five-coordinated high spin dichloro-bridged nicked(Ⅱ)dimmer显示文摘 | Kolnaar J J A Smeets W J J | 1998 | Eur J Inorg Chem1998，，： | 1 |
| 4 | Analysis of differences in growth of cucumber genotypes under low light conditions in relation to night temperature显示文摘 | Nijs A P Smeets L | 1987 | Euphytica1987，36，1： | 1 |
| 5 | Predictive and prognostic value of metabolic tumour volume and total lesion glycolysis in solid tumours显示文摘 | Van de Wiele C Kruse V Smeets P Sathekge M Maes A | 2013 | Eur J Nucl Med Mol Imaging2013，11，40： | 1 |
| 6 | Triple negative breast cancer:clinical characteristics in the different histological sub- types 显示文摘 | Dreyer G Vandorpe T Smeets A | 2013 | Breast2013，22，： | 1 |
| 7 | Beneficial effect of corticosteroids in catecholamine-dependent septic burn patients显示文摘 | Fuchs P Ch Bozkurt A Johnen D Smeets R Groger A Pallua N | 2007 | Burns2007，33，： | 1 |
| 8 | Imagequality performance of liquid crystal display systems: influenceof display resolution,magnification and window settings oncontrast-detail detection 显示文摘 | BACHER K SMEETS P DE HAUWERE A | 2006 | Eur J Radiol2006，58，3： | 1 |
| 9 | Analysis of differences in growth of cucumber genotypes under low light conditions in relation to night temperature显示文摘 | Den Nijs A P M Smeets L | 1987 | Euphytica1987，36，1： | 1 |
| 10 | The cellular red- ox state as a modulator in cadmium and copper responses in Arabidopsis thaliana seedlings 显示文摘 | Cuypers A Smeets K Ruytinx J | 2011 | Journal of Plant Physiology2011，168，： | 1 |
| 11 | Lithium--metal of the future 显示文摘 | Mahi P Smeets A A J Fray D J | 1986 | Journal of the Minerals Metals and Materials Society1986，38，11： | 1 |
| 12 | Energy expenditure,satiety,and plasma ghre-lin ,glucagon-like peptide l,and peptide tyrosine-tyro-sine concentrations following a single high-proteinlunch 显示文摘 | SMEETS A J’SOENEN S LUSCOMBE-MARSH ND | 2008 | The Journal of Nutrition2008，138，4： | 1 |
| 13 | Induction of oxida-tive stress and antioxidative mechanisms in Phaseolus vulgar isafter Cd application 显示文摘 | Smeets K Cuypers A Lambrechts A etal | 2005 | Plant Physiology and Biochemistry2005，43，： | 1 |
| 14 | Metabolic remodelling of the failing heart: the cardiac burn-out syndrome 显示文摘 | Vanbilsen M Smeets P J Glide A J | 2004 | Cardiovasc Res2004，61，2： | 1 |
| 15 | Catalytic chain transfer and its derived macromonomers显示文摘 | Johan P A Heuts Niels M B Smeets | 2011 | Polym Chem2011，，2： | 1 |
| 16 | Extraction of lithium by vacuum thermal reduction with aluminium and silicon 显示文摘 | Smeets A A J Fray D J | 1991 | Transactions of the Institution of Mining and Metallurgy Section C1991，100，： | 1 |
| 17 | Metabolic re-modeling of the failing heart: the cardiac burn-out syndrome? 显示文摘 | Van Bilsen M Smeets PJ Gilde A J | 2004 | Cardiovase Res2004，61，2： | 1 |
| 18 | Protein-induced satiety: Effects and mechanisms of different proteins 显示文摘 | Veldhorst M Smeets A Soenen S | 2008 | Physiol Behav2008，94，2： | 1 |
| 19 | Active re habilitation for chronic low back pain: cognitive-beha- vioral, physical, or both? First direct post treatment re suits from a randomized controlled trial显示文摘 | Smeets R J Vlaeyen J W Hidding A | 2006 | BMC Muscu loskelet Disord2006，7，5： | 1 |
| 20 | Is the sentinel lymph node biopsy more sensitive for the identification of positive lymphnodes in breast cancer than the axillary lymph node dissection? 显示文摘 | Smeets A Yoshihara E Laenen A | 2013 | Springerplus2013，2，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员