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| 1 | Development and validation of RP-HPLC method for estimation of eplerenone in spiked human plasma显示文摘A rapid and simple high performance liquid chromatography(HPLC) method with a UV detection(241 nm) was developed and validated for estimation of eplerenone from spiked human plasma.The analyte and the internal standard(valdecoxib) were extracted with a mixture of dichloromethane and diethyl ether.The chromatographic separation was performed on a HiQSil C-18HS column(250 mm 4.6 mm,5 μm) with a mobile phase consisting of acetonitrile:water(50:50,v/v) at flow rate of 1 mL/min.The calibration curve was linear in the range 100-3200 ng/mL and the heteroscedasticity was minimized by using weighted least squares regression with weighting factor 1/X. | Paraag Gide Sandeep Sonawane Abhishek Chitnis | 2012 | Journal of Pharmaceutical Analysis2012，2，5： | 2 |
| 2 | Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride- channel gating显示文摘 | Pedemonte N Sonawane N D Taddei A | 2005 | Mol Pharmacol2005，67，5： | 1 |
| 3 | Application of Mitscherlic - Bray Equation for Fertilizer Use in Peari Millet on Vertisol显示文摘 | Sonawane S S and Sonar K R | 1995 | Journal of the Indian Society of Soil Science1995，43，2： | 1 |
| 4 | Role of heat transfer and thermal conductivity in the crystallization behavior of polypropylene-containing additives:A phenomenological model显示文摘 | Sonawane P S Radhakrishnan S | 2003 | J Appl Polym Sci2003，89，11： | 1 |
| 5 | Early envi- ronmental origins of neurodegenerative disease in later life 显示文摘 | LANDRIGAN P J SONAWANE B BUTLER RN | 2005 | Envi- ron Health Perspect2005，113，9： | 1 |
| 6 | Discovery of gly- cine hydrazide Pore- occluding CFrR inhibitors: mechanism, structure - activity analysis ,and in vivo efficacy显示文摘 | Muanprasat C Sonawane N D Salinas D | 2004 | J Gen Phys- iol2004，124，2： | 1 |
| 7 | Design of a Gravity Corer for Near Shore Sediment Sampling显示文摘 | Bhat S T Sonawane A V Nayak B U | 1992 | Indian Journal of Marine Sciences1992，3，21： | 1 |
| 8 | Role of glycans and glycoproteins in disease development by Mycobacterium tuberculosis显示文摘 | Sonawane A Mohanty S Jagannathan L | 2012 | Crit Rev Microbiol2012，38，3： | 1 |
| 9 | Preparation of titanium ( Ⅳ ) oxide thin film photocatalyst by sol-gel dip coating显示文摘 | Hegde S G Dongare M K | 2002 | Mater Chem Phys2002，77，： | 1 |
| 10 | Sol-gel synthesis of Au/TiO2 thin films for photocatalytic degradation of phenol in sunlight显示文摘 | DONGARE M K | 2006 | Journal of Molecular Catalysis A:Chemienl2006，，243： | 1 |
| 11 | Neurodegenerative disea- ses: an overview of environmental risk factors 显示文摘 | Brown RC Lockwood AH Sonawane BR | 2005 | Environ Health Perspect2005，113，9： | 1 |
| 12 | QSAR,docking studies and pharmacophore identification of phenylmethyl phenoxy propyl amino propanoic acid derivatives as leukotriene A_4 hydrolase inhibitors显示文摘The enzyme leukotriene A4 (LTA4) plays an important role as precursor of slow reactive substances as LTC4, LTD4, and LTE4. It is an attractive target for molecular modeling and QSAR study. Our effort is mainly focused on exploring the SAR for inhibitors of the LTA4 hydrolase through docking study, pharmacophore modeling and molecular descriptor study. The binding of these small molecules on LTA4 hydrolase enzyme was described by the models developed on 2D molecular descriptors, with good predictive power (39 compounds, 6 descriptors, r2 0.98, SEE 0.167, F-value 268.53, q2 0.90, r2adj 0.97, P-value < 0.0001, SD of residuals 0.15). Docking studies were employed to presume the probable binding conformation of these analogues and exploring the SAR for the compounds. The novel pharmacophore represents the ligand features that are involved in interactions with the target protein, as well as the space around the ligand occupied by the protein. The efforts are aimed to discover the SAR for the inhibitors of LTA4 hydrolase through techniques of QSAR, docking and pharmacophore. | SONAWANE Lalit V BARI Sanjaykumar B | 2010 | 药学学报2010，45，5： | 1 |
| 13 | Preparation and pho- to-catalytic activity of Fe-TiO2 thin films prepared by sol-gel dip coating 显示文摘 | Sonawane R S Kale B B Dongare M K | 2004 | Materials Chemistry and Physics2004，85，1： | 1 |
| 14 | 2-aminothiophenes by the Gewald reaction显示文摘 | Rangnekar S R W Sonawane N D J | 1999 | Heterocycl Chem1999，36，2： | 1 |
| 15 | A New Equation for the Correlation of Surface Tension-Composition Data of Solvent-Solvent and Solvent-Fused Salt Mixtures 显示文摘 | Sonawane P D Kumar A | 1999 | FluidPhase Equilib1999，157，1： | 1 |
| 16 | Preparation and photo-catalytic activity of Fe-TiO2 thin films prepared by sol-gel dip coating 显示文摘 | SONAWANE R S KALE B B DONGARE M K | 2004 | Materials Chemistry and Physics2004，85，1： | 1 |
| 17 | Preparation and photo-catalytic activity of Fe-TiO2 thin films prepared by sol-gel dip-coating显示文摘 | Sonawane R S Kale B B Dongare M K | 2005 | Materials Chemistry and Physics2005，85，： | 1 |
| 18 | The safety of heparinis in end-stge renal disease显示文摘 | Sonawane S Kasbekar N Berns J S | 2006 | Semin Dial2006，19，5： | 1 |
| 19 | An Analytical Model to Predict Specific Shear Energy in High-Speed Turning of Inconel 718 显示文摘 | Pawade R S Sonawane H A Joshi S S | 2009 | International Journal of Machine Tools and Manufacture (S0890-6955)2009，49，1213： | 1 |
| 20 | Preparation of titanium (Ⅳ) oxide thin film photocatalyst by sol-gel dip coating显示文摘 | Sonawane R S Hegde S G Dongare M K | 2003 | Materials Chemistry and Physics2003，77，3： | 1 |
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