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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | A systematic study of bovine serum albumin (BSA) and sodium dodecyl sulfate (SDS) in- teractions by surface tension and small angle X-ray scattering显示文摘 | Sonia F S Dino Z Hannes F | 2003 | Journal of Colloid and Interface Science2003，262，2： | 1 |
| 3 | Chromosome numbers and behavior in some species of Dioscorea显示文摘 | Martin F W Sonia O | 1963 | Cytologia1963，28，： | 1 |
| 4 | Final contractor se- lection using the analytical hierarchy process 显示文摘 | PATRICK S W F SONIA K Y C | 2000 | Construction Management and Economics2000，18，5： | 1 |
| 5 | Early oxidative damage in prima-ry cultured trout hepatocytes:a time course study显示文摘 | MICHELA F SONIA R PAOLO C | 2002 | Aquatic Toxicology2002，59，34： | 1 |
| 6 | Natural pollination, hand pollination and crossability of some Mexican species of Dioscorea 显示文摘 | Martin F W Cabanillas E Sonia O | 1963 | Trop Agric Trin1963，40，2： | 1 |
| 7 | Regulation of mineral nitrogen uptake in plants显示文摘 | Nicolaus yon W Sonia Ga Wolf B F | 1997 | Plant and Soil1997，196，2： | 1 |
| 8 | Osteopetrosis with carbonic anhydrase Ⅱ deficiency:report of 24 cases显示文摘 | Sonia HL Mohamed F Mohamed B | 2005 | Tunis Med2005，83，7： | 1 |
| 9 | L-carnitine reduces lymphocyte apoptosis and oxidant stress in HIV-1-infected subjects treated with zidovudine and didanosine显示文摘 | MORETTI S GIUSEPPE F SONIA M | 2000 | Antioxidants & Redox Signaling2000，4，： | 1 |
| 10 | Rejection after conversion to a proliferation signal inhibitor in chronic heart transplantation显示文摘 | Francisco González‐Vílchez José A. Vázquez de Prada María J. Paniagua Luis Almenar Sonia Mirabet Manuel Gómez‐Bueno Beatriz Díaz‐Molina Jose M. Arizón Juan Delgado Félix Pérez‐Villa María G. Crespo‐Leiro Luis Martínez‐Dolz Eulalia Roig Javier Segovia José | 2013 | Clin Transplant2013，，6： | 1 |
| 11 | Characterization of an hyper-pig- menting mutant of Monascus purpureus IBI: identification of two novel pigment chemical structures 显示文摘 | Sonia C Angel R Juan F | 2006 | Applied Microbiology and Biotechnology2006，70，： | 1 |
| 12 | Early oxidative damage in primary cultured trout hepatocytes:a time course study显示文摘 | Michela F Sonia R Paolo C | 2002 | Aquatic Toxicology2002，，59： | 1 |
| 13 | Heed : A hybrid energy - efficient distribu- ted clustering approach for ad - hoc sensor networks 显示文摘 | Ossama Y Sonia F | | IEEE Transactions on mobile computing0，，： | 1 |
| 14 | Relationship between delayed diagnosis and the degree of invasion and survival in lung cancer显示文摘 | Salvador P F Carmen M M Sonia P D | 2003 | Journal of Clinical Epidemiology2003，56，9： | 1 |
| 15 | Identification of anthocyanin pigments in strawberry (cv Camarosa) by LC using DAD and ESI-MS detection显示文摘 | Fátima Lopes-da-Silva Sonia de Pascual-Teresa Julián Rivas-Gonzalo Celestino Santos-Buelga | 2002 | European Food Research and Technology2002，，3： | 1 |
| 16 | Caesalpinin,A Rearranged Cassane Furanoditerpene of Caesalpinia bonducella显示文摘 | Tinto Winston F Mclean Stewart | 1997 | Tetrahedron Lett1997，38，33： | 1 |
| 17 | Efficacy and safety of sitosterol in the management of blood cholesterol levels 显示文摘 | Maria L F Sonia V L | 2005 | Cardiovascular Drug Reviews2005，23，1： | 1 |
| 18 | Gluten immunogenic peptide excretion detects dietary transgressions in treated celiac disease patients显示文摘BACKGROUND Life-long removal of gluten from the diet is currently the only way to manage celiac disease(CeD). Until now, no objective test has proven useful to objectively detect ingested gluten in clinical practice. Recently, tests that determine consumption of gluten by assessing excretion of gluten immunogenic peptides(GIP) in stool and urine have been developed. Their utility, in comparison with conventional dietary and analytical follow-up strategies, has not been fully established.AIM To assess the performance of enzyme-linked immunosorbent assay(ELISA) and point-of-care tests(PoCTs) for GIP excretion in CeD patients on gluten-free diet(GFD).METHODS We conducted an observational, prospective, cross-sectional study in patients following a GFD for at least two years. Using the Gastrointestinal Symptom Rating Scale questionnaire, patients were classified at enrollment as asymptomatic or symptomatic. Gluten consumption was assessed twice by 3-d dietary recall and GIP excretion(by ELISA in stool and PoCTs(commercial kits for stool and urine) in two consecutive samples. These samples and dietary reports were obtained 10 day apart one from the other. Patients were encouraged to follow their usual GFD during the study period.RESULTS Forty-four patients were enrolled, of which 19(43.2%) were symptomatic despite being on a GFD. Overall, 83 sets of stool and/or urine samples were collected.Eleven out of 44 patients(25.0%) had at least one positive GIP test. The occurrence of at least one positive test was 32% in asymptomatic patients compared with 15.8% in symptomatic patients. GIP was concordant with dietary reports in 65.9% of cases(Cohen′s kappa: 0.317). PoCT detected dietary indiscretions. Both ELISA and PoCT in stool were concordant(concomitantly positive or negative) in 67 out of 74(90.5%) samples. Excretion of GIP was detected in 7(8.4%) stool and/or urine samples from patients considered to be strictly compliant with the GFD by dietary reports.CONCLUSION GIP detects dietary transgressions in patients on long-term GFD, irrespective of the presence of symptoms. PoCT for GIP detection constitutes a simple homebased method for self-assessment of dietary indiscretions. | Ana Florencia Costa Emilia Sugai María de la Paz Temprano Sonia Isabel Niveloni Horacio Vázquez María Laura Moreno M.Remedios Domínguez-Flores Alba Mu?oz-Suano Edgardo Smecuol Juan Pablo Stefanolo Andrea F González Angel Cebolla-Ramirez Eduardo Mauri?o Elena F Verdú Julio César Bai | 2019 | World Journal of Gastroenterology2019，25，11： | 1 |
| 19 | Evaluation of synthetic iron (Ⅲ)-chelates (EDDHA/Fe3+,EDDHMA/Fe3 and the novel EDDHSA/Fe3+) to correct iron chlorosis显示文摘 | Ana A F Sonia G M Juan J L | 2005 | European Journal of Agronomy2005，22，： | 1 |
| 20 | Complete ^1H and ^13C-NMR assignments of four caesalpin furanoditerpenes of caesalpinia bonducella显示文摘 | SONIA R P WINSTON F T STEWART M | 1998 | Magnetic Resonance in Chemistry1998，36，2： | 1 |
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