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| 1 | Leukemia:研究鉴定出与34种AML白血病亚群相关联的基因突变显示文摘针对成年急性髓细胞白血病(acute myeloid leukemia,AML)患者的一项新的大型研究将80种癌症相关基因突变与5种AML亚型相关联。这5种AML亚型可通过特异性的染色体异常加以确定。在未来,这些发现可能有助指导基因突变测试和治疗决策。 | A-K Eisfeld K Mrózek J Kohlschmidt D Nicolet S Orwick C J Walker K W Kroll J S Blachly A J Carroll J E Kolitz B L Powell E S Wang R M Stone A de la Chapelle J C Byrd C D Bloomfield | 2017 | 现代生物医学进展2017，17，15： | 7 |
| 2 | Dyslipidemia management in primary prevention of cardiovascular disease:Current guidelines and strategies显示文摘Cardiovascular disease is the leading cause of death in the United States. In 2010, the Centers for Disease Control and Prevention estimated that $444 billion was spent on cardiovascular diseases alone, about $1 of every $6 spent on health care. As life expectancy continues to increase, this annual cost will also increase, making costeffective primary prevention of cardiovascular disease highly desirable. Because of its role in development of atherosclerosis and clinical events, dyslipidemia management is a high priority in cardiovascular prevention. Multiple major dyslipidemia guidelines have been published around the world recently, four of them by independent organizations in the United States alone. They share the goal of providing clinical guidance on optimal dyslipidemia management, but guidelines differ in their emphasis on pharmacotherapy, stratification of groups, emphasis on lifestyle modification, and use of a fixed target or percentage reduction in low density lipoprotein cholesterol. This review summarizes eight major guidelines for dyslipidemia management and considers the basis for their recommendations. Our primary aim is to enhance understanding of dyslipidemia management guidelines in patient care for primary prevention of future cardiovascular risk. | Aditya D Hendrani Tolulope Adesiyun Renato Quispe Steven R Jones Neil J Stone Roger S Blumenthal Seth S Martin | 2016 | World Journal of Cardiology2016，8，2： | 5 |
| 3 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 4 | Comparison of outcomes of diabetic and nondiabetic patients undergoing primary angioplasty for acute myocardial infarction显示文摘 | Harjai K J Stone GW Boura J | 2003 | Am J Cardiol2003，91，9： | 2 |
| 5 | Experience with PDA diagnostic testing on hydraulic generators显示文摘 | Lyles J F Stone G C Kurtz M | 1998 | IEEE Trans on E C1998，3，4： | 2 |
| 6 | Chiral recognition of non-natural α-amino acids显示文摘 | GAL J F STONE M LEBRILLA C B | 2003 | Int J Mass Spectrom2003，222，123： | 1 |
| 7 | HAESA, an Arabidopsis leucinerich repeat receptor kinase, controls floral organ abscission 显示文摘 | Lin T L Stone J Walker J | 2000 | Genes Dev2000，14，： | 1 |
| 8 | Cancer resistance, carcinogenesis and ground sub stance viscosity 显示文摘 | Stone O J | 1986 | Med Hypotheses1986，20，1： | 1 |
| 9 | Impact of normalized myocardial perfusion after successful angioplasty in acute myocardial infarction 显示文摘 | STONE G W PETERSON M A LANSKY A J | 2002 | J Am Coll Cardiol2002，39，： | 1 |
| 10 | Expression of multiple pili by Legionella pneu- mophila : identification and characterization of a type IV pilin gene and its role in adherence to mammalian and protozoan cells显示文摘 | Stone B J Abu Kwaik Y | 1998 | Infect Immun1998，66，4： | 1 |
| 11 | A pilot study of rhuIL-11 treatment of refractory ITP 显示文摘 | Bussel J B Mukherjee R Stone A J | 2001 | Am J Hematol2001，66，3： | 1 |
| 12 | Spinal cord injury in children: long-term urodynamic and urological outcomes 显示文摘 | Generao S E Dall' era J P Stone A R | 2004 | J Urol2004，172，3： | 1 |
| 13 | Educational interventions in kidney disease care:a systematic review of randomized trials显示文摘 | Mason J Khunti K Stone M | 2008 | Am J Kidney Dis2008，51，6： | 1 |
| 14 | Impact of normalized myocardial perfusion after successful angioplasty in acute myocardial infarction显示文摘 | STONE G W PETERSON M A LANSKY A J | 2002 | J Am Coll Cardiol2002，39，： | 1 |
| 15 | Silicon single electron memory cell 显示文摘 | Stone N J Ahmed H | 1998 | Appl Phys Lett1998，73，15： | 1 |
| 16 | Rapid purification of staphylococcal enterotoxin B by high-pressure liquid chromatography显示文摘 | Strickler M P Neill R J Stone M J | 1989 | J Clin Microbiol1989，27，5： | 1 |
| 17 | Detection of NO in a spark-ignition research engine using degenerate four-wave mixing显示文摘 | GRANT A J EWART P STONE C R | 2002 | Applied Physics B-Lasers and Optics2002，74，1： | 1 |
| 18 | Management of the major coagulopathy with onset during iaparotomy 显示文摘 | STONE H H STORM P R MULLINS R J | 1983 | Ann Surg1983，197，5： | 1 |
| 19 | Stress related effects of hatchery rearing density on coho salmon显示文摘 | Fagcrlund U M Mcbride J R Stone E T | 1981 | Transactions of the American Fisheries Society1981，110，5： | 1 |
| 20 | Seasonal and diurnal body-mass fluctuations for two nonhoarding species ofparus in Sweden modeled using path analysis显示文摘 | Rintamaki P T Stone J R Lundberg S A | 2003 | Auk2003，120，3： | 1 |
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