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| 1 | Long-term results of endosurgical and open surgical approach for Zenker diverticulum显示文摘AIM: To assess the effectiveness of minimally invasive versus traditional open surgical approach in the treatment of Zenker diverticulum. METHODS: Between 1976 and 2006, 297 patients underwent transoral stapling (n = 181) or stapled diverticulectomy and cricopharyngeal myotomy (n = 116). Subjective and objective evaluations of the outcome of the two procedures were made at 1 and 6 mo after operation, and then every year. Long-term follow-up data were available for a subgroup of patients at a minimum of 5 and 10 years. RESULTS: The operative time and hospital stay were markedly reduced in patients undergoing the endosurgical approach. Overall, 92% of patients undergoing the endosurgical approach and 94% of those undergoing the open approach were symptom-free or were significantly improved after a median follow-up of 27 and 48 mo, respectively. At a minimum follow-up of 5 and 10 years, most patients were asymptomatic after both procedures, except for those individuals undergoing an endosurgical procedure for a small diverticulum (< 3 cm). CONCLUSION: Both operations relieve the outflow obstruction at the pharyngoesophageal junction, indicating that cricopharyngeal myotomy has an important therapeutic role in this disease independent of the resection of the pouch and of the surgical approach. Diverticula smaller than 3 cm represent a formal contraindication to the endosurgical approach because the common wall is too short to accommodate one cartridge of staples and to allow complete division of the sphincter. | Luigi Bonavina Davide Bona Medhanie Abraham Greta Saino Emmanuele Abate | 2007 | World Journal of Gastroenterology2007，13，18： | 4 |
| 2 | Using the BirdTree.org website to obtain robust phylogenies for avian comparative studies: A primer显示文摘 | Diego RUBOLINI Andras LIKER Laszlo Z. GARAMSZEGI Anders P. MOLLEIR Nicola SAINO | 2015 | Current Zoology2015，61，6： | 3 |
| 3 | Current status of minimally invasive endoscopic management for Zenker diverticulum显示文摘Surgical resection has been the mainstay of treatment of pharyngoesophageal(Zenker) diverticula over the past century. Developments in minimally invasive surgery and new endoscopic devices have led to a paradigm change. The concept of dividing the septum between the esophagus and the pouch rather than resecting the pouch itself has been revisited during the last three decades and new technologies have been investigated to make the transoral operation safe and effective. The internal pharyngoesophageal myotomy accomplishedthrough the transoral stapling approach has been shown to effectively relieve outflow obstruction and restore physiological bolus transit in patients with medium size diverticula. Transoral techniques, either through a rigid device or by flexible endoscopy, are gaining popularity over the open surgical approach due the low morbidity, the fast recovery time and the fact that the procedure can be safely repeated. We provide an analysis of the the current status of minimally invasive endoscopic management of Zenker diverticulum. | Alberto Aiolfi Federica Scolari Greta Saino Luigi Bonavina | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，2： | 2 |
| 4 | Materal thrombocytopenia atterm a population - based study 显示文摘 | Saino S KckarakiR Riikoncn S | 2000 | Obstet Gynecol Scand2000，79，9： | 1 |
| 5 | 5 New Triterpene Glyco- sides from Wistefia-brachybotrys(leguminosae)显示文摘 | Kinjo J Fujishima Y Saino K | 1995 | Chemical & Pharmaceutical Bulletin1995，43，4： | 1 |
| 6 | Magnetic augmentation of the lower esophageal sphincter: results of a feasibility clinical trial 显示文摘 | Bonavina L Saino GI Bona D | 2008 | J Gastrointest Surg2008，12，12： | 1 |
| 7 | Nestin expression in central nervous system germ cell tumors 显示文摘 | Sakurada K Saino M Mouri W | 2008 | Neurosurg Rev2008，31，2： | 1 |
| 8 | Modulation of sympathetic coronary vasoconstriction by cardiac rennin angiotsnsin system in human coronary artery disease显示文摘 | Saino A Pomidossi G Perondi R | 2000 | Circulation2000，101，： | 1 |
| 9 | In vitro calcified matrix deposition by human osteoblasts onto a zinc-containing bioactive glass显示文摘 | Saino E Grandi S Quartarone E | 2011 | Eur Cell Mater2011，21，2： | 1 |
| 10 | Early maternal effects and antibacterial immune factors in the eggs, nestlings and adults of the barn swallow 显示文摘 | Saino N Dallara P Martinelli R | 2002 | Journal of Evolutionary Biology2002，15，： | 1 |
| 11 | Magnetic augmentation of the lower esophageal sphincter: results of a feasibility clinical trial 显示文摘 | Bonavina L Saino GI Bona D | 2008 | J Gastroi-ntest Surg2008，12，12： | 1 |
| 12 | Early maternal effects mediated by immunity depend on sexual ornamentation of the male partner 显示文摘 | Saino N Ferrari R P Martinelli R | 2002 | Proceedings of the Royal Society B2002，269，： | 1 |
| 13 | Human digit ratios depend on birth order and sex of older siblings and predict maternal fecundity显示文摘 | Saino N Leoni B Romano M | 2006 | Behav Ecol Sociobiol2006，60，1： | 1 |
| 14 | Carotenoid concentration in barn swallow eggs is influenced by laying order, maternal infection and paternal ornamentation显示文摘 | Saino Nicola Bertacche Vittorio Ferrari Raffaella Paola Martinelli Roberta M? ller Anders Pape Stradi Riccardo | 2002 | Proceedings of the Royal Society B: Biological Sciences . 2002 (1501)2002，，： | 1 |
| 15 | Matemalthrombocytopenia, at term:a population-based study显示文摘 | Saino S Kekomaki R Riikonen S | 2000 | Acta Obstet Gynecol Scand2000，79，9： | 1 |
| 16 | Preparation and anti- HIV activity of low-molecular weight carrageenans and their sulfatedderivatives显示文摘 | Yamada T Ogamo A Saino T | 1997 | Carbohyd Polym1997，32，1： | 1 |
| 17 | Magnetic augmentation of the low-er esophageal sphincter: results of a feasibility clinical trial显示文摘 | Bonavina L Saino GI Bona D | 2008 | J Gas-trointest Surg2008，12，12： | 1 |
| 18 | Synthesis and structure-activity relations of hestatin analogs,inhibitors of aminopeptidase B显示文摘 | Nishizawa R Saino T Takita T | 1977 | J Med Chem1977，20，4： | 1 |
| 19 | Ecological conditions during winter predict arrival date at breeding quarters in a trans-Saharan migratory bird显示文摘 | Saino N Sz6p T Romano M | 2004 | Ecology Letters2004，7，1： | 1 |
| 20 | Nestin expression in central nervous system germ cell tumors 显示文摘 | Sakurada K Saino M Mouri W | 2008 | Neurosurg Rev2008，31，2： | 1 |
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