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| 1 | Identification of pathologic features associated with “ulcerative colitis-like” Crohn's disease显示文摘AIM: To identify pathologic features associated with this 'ulcerative colitis(UC)-like' subgroup of Crohn's disease(CD).METHODS: Seventeen subjects diagnosed as having UC who underwent proctocolectomy(RPC) from 2003-2007 and subsequently developed CD of the ileal pouch were identified. UC was diagnosed based on preoperative clinical, endoscopic, and pathologic studies. Eighteen patients who underwent RPC for UC within the same time period without subsequently developing CD were randomly selected and used as controls. Pathology reports and histological slides were reviewed for a wide range of gross and microscopic pathological features, as well as extent of disease. The demographics, gross description and histopathology of the resection specimens were reviewed and compared between the two groups. RESULTS: Patients with 'UC-like' CD were on average 13 years younger than those with 'true' UC(P < 0.01). More severe disease in the proximal involved region and active ileitis with/without architectural distortion were observed in 6 of 17(35%) and 7 of 17(41%) 'UC-like' CD cases, respectively, but in none of the 'true' UC cases(P < 0.05). Active appendicitis occurred in 8 of 16(50%) 'UC-like' CD cases but in only two(11%) 'true' UC cases(P < 0.05). Conspicuous lamina propria neutrophils were more specific for 'UClike' CD(76% vs 22%, P < 0.05). In addition, prominent lymphoid aggregates tended to be more common in 'UC-like' CD(P = 0.07). The 'true' UC group contained a greater number of cases with severe activity(78% vs 47%). Therefore, the features more commonly seen in 'UC-like' CD were not due to a more severe disease process. Crohn's granulomas and transmural inflammation in non-ulcerated areas were absent in both groups.CONCLUSION: More severe disease in the proximal involved region, terminal ileum involvement, active appendicitis, and prominent lamina propria neutrophils may be morphological factors associated with 'UC-like' CD. | Samuel D James Paul E Wise Tania Zuluaga-Toro David A Schwartz M Kay Washington Chanjuan Shi | 2014 | World Journal of Gastroenterology2014，20，36： | 4 |
| 2 | Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression显示文摘 | Yoo Byoung Kwon Emdad Luni Su Zao-zhong Villanueva Augusto Chiang Derek Y Mukhopadhyay Nitai D Mills Alan Scott Waxman Samuel Fisher Robert A Llovet Josep M Fisher Paul B Sarkar Devanand | 2009 | Journal of Clinical Investigation2009，，3： | 2 |
| 3 | Cloning and sequencing of a Shiga - like toxin type II variant from Esche- richia coli strain responsible for edema disease of swine 显示文摘 | WEINSTEIN D L JACKSON M P SAMUEL J E | 1988 | Bacteri- ol1988，170，9： | 1 |
| 4 | Cloning and sequencing of a Shiga-like toxin type Ⅱ variant from Escherichia coli strain responsible for edema disease of swine显示文摘 | WEINSTEIN D L JACKSON M P SAMUEL J E | 1988 | J Bacteriol1988，170，9： | 1 |
| 5 | Al partitioning patterns and root growth as related to Al sensitivity and Al tolerance in wheat 显示文摘 | SAMUELS T D KUCUKAKYUZ K RINCON-ZACHARY M | 1997 | Plant Physiol1997，113，2： | 1 |
| 6 | Randomized trial of postoperative adjuvant chemotherapy with or without radiother- apy for Ccareinoma of the rectum : National Surgical Adjuvant Breast and Bowel Project Protocol R -02 显示文摘 | Norman Wolmark Samuel Wieand H Hyams D M | 2000 | Journal of the National Cancer Institute2000，92，5： | 1 |
| 7 | Effects of solifenacin on overactive bladder symptoms, symptom bother and other patient-reported outcomes: results from VIBRANT-a double-blind, placebo-controlled trial显示文摘 | Vardy M D Miteheson H D Samuels T A | 2009 | Int J Clin Pract2009，63，12： | 1 |
| 8 | Mobility and deposition of silicon in cucumber plants 显示文摘 | SAMUELS A L GLASS A D M | 1991 | Plant Cell and Environ- ment1991，14，： | 1 |
| 9 | Electromagnetic aircraft launch system-EMALS显示文摘 | Doyle M R Samuel D J Conway T | 1995 | IEEE Transactions on Magnetics1995，31，2： | 1 |
| 10 | Cellular pathways regulating responses to compatible and self-incompatible pollen in Brassica and Arabidopsis stigmas intersect at Exo70A1,a putative component of the exocyst complex显示文摘 | Samuel M A Chong Y T Haasen K E Aldea-Brydges M G Stone S L Goring D R | | 0，，09： | 1 |
| 11 | Convective flat-plate solar heat collector for cauliflower drying显示文摘 | Dattatreya M K Samuel D V K | 2006 | Biosystems Engineering2006，93，2： | 1 |
| 12 | Pho- tophysical characterization of poly ( p - pyridine ) 显示文摘 | Monkman A P Halim M Dailey S Samuel I D M Horsbrugh L | 1999 | Synthetic Met- als1999，101，： | 1 |
| 13 | Aligning strategic human resource management and person-environment fit 显示文摘 | James D Werbel Samuel M DeMarie | 2005 | Human Resource Management Review2005，15，4： | 1 |
| 14 | A meta-analysis of unrelated donor umbilical cord blood transplantation versus unrelated donor bone marrow transplantation in adult and pediatric patients 显示文摘 | Hwang WY Samuel M Tan D | 2007 | Biol Blood Marrow Transplant2007，13，4： | 1 |
| 15 | ElSe Aircraft Launch System-EMALS显示文摘 | Doyle M R Samuel D J Conway T | 1995 | IEEE Transactions on Magnetics1995，31，1： | 1 |
| 16 | Neoadjuvant and adjuvant therapy for surgical resection of hepatocellular carcinoma显示文摘 | Samuel M Chow PK Chan Shih-Yen E Machin D Soo KC | | 0，，01： | 1 |
| 17 | The un-predictable nature of internal tides on continental shelves显示文摘 | Nash Jonathan D Kelly Samuel M Shroyer Emily L | | 0，，： | 1 |
| 18 | 黄粉虫替代蛋白质饲料对太平洋白虾(凡纳滨对虾)消化性能的影响显示文摘试验旨在评估黄粉虫粉(MM)作为凡纳滨对虾养殖中蛋白质来源的可行性。饲料分为正常饲料和试验饲粮,试验饲料中包含正常饲料85%和MM 15%,两种饲料中均含有氧化铬0.5%作为惰性标记,试验采用表观消化率系数(ADC)对两种饲料进行检测。为评估MM消化价值,对虾饲料中采用鱼粉替代MM,替代比例分别为0%、25%、50%、75%和100%,在清水中饲养6周后,对生长参数和整个虾体成分进行评估。干物质ADC为45.9%,能量ADC为66.5%,粗蛋白质ADC为76.1%,必须氨基酸ADC为72%~86%。MM中蛋氨酸为第一限制性氨基酸。饲料中添加MM后,各组间对虾的体增重、特定生长率、采食量、饲料转化率、存活率和蛋白质合成率均无显著变化(P>0.05),虾体蛋白质含量无显著差异(P>0.05)。而随着鱼粉替代比例上升,虾体脂含量从1.13%升至1.88%。结果表明,黄粉虫粉可作为凡纳滨对虾饲料中的替代蛋白质饲料,但添加时应注意补充蛋氨酸。 | Panini R L Freitas L E L Guimarǎes A M Rios C da Silva M F O Vieira F N Fracalossi D M Samuels R I | 2017 | 饲料博览2017，0，7： | 1 |
| 19 | Electromagnetic aircraft launch system-EMALS显示文摘 | Doyle M R Samuel D J Conway T | 1995 | IEEE Transactions on Magnetics1995，31，1： | 1 |
| 20 | Immunofluo- rescent localization of plasmamembrane H^+-ATPase in barley- roots and effects of K nutrition 显示文摘 | SAMUELS A L FERNANDO M GLASS A D M | 1992 | Plant Physiology1992，99，4： | 1 |
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