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| 1 | Predictors of mortality after transjugular portosystemic shunt显示文摘AIM:To investigate if echocardiographic and hemodynamic determinations obtained at the time of transjugular intrahepatic portosystemic shunt(TIPS)can provide prognostic information that will enhance risk stratification of patients.METHODS:We reviewed medical records of 467 patients who underwent TIPS between July 2003 and December 2011 at our institution.We recorded information regarding patient demographics,underlying liver disease,indication for TIPS,baseline laboratory values,hemodynamic determinations at the time of TIPS,and echocardiographic measurements both before and after TIPS.We recorded patient comorbidities that may affect hemodynamic and echocardiographic determinations.We also calculated Model for Endstage Liver Disease(MELD)score and Child Turcotte Pugh(CTP)class.The following pre-and post-TIPS echocardiographic determinations were recorded:Left ventricular ejection fraction,right ventricular(RV)systolic pressure,subjective RV dilation,and subjective RV function.We recorded the following hemodynamic measurements:Right atrial(RA)pressure before and after TIPS,inferior vena cava pressure before and after TIPS,free hepatic vein pressure,portal vein pressure before and after TIPS,and hepatic venous pressure gradient(HVPG).RESULTS:We reviewed 418 patients with portal hypertension undergoing TIPS.RA pressure increased by a mean ± SD of 4.8 ± 3.9 mmH g(P < 0.001),HVPG decreased by 6.8 ± 3.5 mmH g(P < 0.001).In multivariate linear regression analysis,a higher MELD score,lower platelet count,splenectomy and a higher portal vein pressure were independent predictors of higher RA pressure(R = 0.55).Three variables predicted 3-mo mortality after TIPS in a multivariate analysis:Age,MELD score,and CTP grade C.Change in the RA pressure after TIPS predicted long-term mortality(per 1 mm Hg change,HR = 1.03,95%CI:1.01-1.06,P < 0.012).CONCLUSION:RA pressure increased immediately after TIPS particularly in patients with worse liver function,portal hypertension,emergent TIPS placement and history of splenectomy.The increase in RA pressure after TIPS was associated with increased mortality.Age,splenectomy,MELD score and CTP grade were independent predictors of long-term mortality after TIPS. | Mona Ascha Sami Abuqayyas Ibrahim Hanouneh Laith Alkukhun Mark Sands Raed A Dweik Adriano R Tonelli | 2016 | World Journal of Hepatology2016，8，11： | 13 |
| 2 | Is cardiac resynchronisation therapy feasible, safe and beneficial in the very elderly?显示文摘ObjectiveTo evaluate 心脏的同一时刻治疗(CRT ) 培植是否与经历 CRT 培植的 symptoms.MethodsConsecutive 病人一起在 octogenarians 和协会可行、安全,从二个英国中心被招募。根据年龄组织的病人:<80 &≥80 年。基线人口分布,复杂并发症和结果在 439 个病人的那些 groups.ResultsA 总数之间被比较在这研究, 26%≥ 是谁被包括;80 年。Octogenarians 更经常与心脏的同一时刻治疗使用高压脉冲来消减心脏相比收到了心脏的再同步治疗心律调整器。从心律调整器的升级在两个组是普通的(16%<80 年对 22%≥80 年, P = NS ) 。合作病态在两个组是同样普通的(全面糖尿病:25% , atrial 纤维性颤动:23% ,高血压:45%) 。更耐心的年龄 ≥80 年有重要的长期的肾疾病(CKD,估计的 glomerular 过滤率 <45 mL/min 每 1.73 m 2,44% 对 22% , P <0.01 ) 。全面复杂并发症率(任何东西) 在两个组是类似的(16% 对 17% , P = NS ) 。两个组表明了征兆的利益。一个年死亡率作为与更年轻的队相比是在 octogenarians 更大的几乎四褶层(13.9% 对 3.7% , P <0.01 ).ConclusionsCRT 看起来安全在尽管有广泛的合作病态老、特别地经常严重 CKD。征兆的改进看起来有意义。增加的策略是 CRT 的潜在的候选人的有 CHF 的老病人的适当鉴定被要求。 | Bartosz Olechowski Rebecca Sands Donah Zachariah Neil P Andrews Richard Balasubramaniam Mark Sopher John Paisey Paul R Kalra | 2015 | Journal of Geriatric Cardiology2015，12，5： | 5 |
| 3 | Post-ERCP pancreatitis: Reduction by routine antibiotics显示文摘 | Sari R?ty M.D. Juhani Sand M.D. Markku Pulkkinen S.R.N. Martti Matikainen M.D. Isto Nordback M.D | 2001 | Journal of Gastrointestinal Surgery2001，，4： | 3 |
| 4 | Efficacy and safety of low dose desmopressin orally disintegra- ti'ng tablet in women with nocturia: Results of a multi- center, randomized, double-blind, placebo controlled, parallel group study显示文摘 | Sand P K Dmoehowski R R Reddy J | 2013 | J Urol2013，190，3： | 1 |
| 5 | Crystallization of EU-1 and EU-2 in Alkali and Alkali-Free Systems显示文摘 | Dodwell G W Denkewicz R P Sand L B | 1985 | Zeolites1985，5，： | 1 |
| 6 | Ferroelectric La-Sr-Co/Pb-Zr-Ti-O/La-Sr-Co-O Heterostructures on Silicon via Template Growth 显示文摘 | Ramesh R Glichrist H Sands T | 1993 | Appl Phys Lett1993，63，26： | 1 |
| 7 | The Effect of Nitrogenon Stacking Fault Energy of Fe-Ni-Cr-Mn Steels显示文摘 | Stoltz R E Vander Sande J B | 1980 | MetTrans1980，11，6： | 1 |
| 8 | Quantification of the process of seeondary xylem fibre development in Eucalyptus globules at two height levels显示文摘 | Ridoutt B G Sands R | 1994 | IAWA J1994，15，： | 1 |
| 9 | Lymph node metastasis in thyroid papillary microcarcinoma: a study of 170 patients显示文摘 | Varshney R Pakdaman MN Sands N | 2014 | J Laryngol Otol2014，128，10： | 1 |
| 10 | Efficacy, safety and tolerability of fesoterodine for overactive bladder syndrome显示文摘 | Nitti VW Dmochowski R Sand PK | 2007 | J Urol2007，178，6： | 1 |
| 11 | Polymers to direct cell fate by controlling the microenvironment显示文摘 | Sands R W | | 0，，05： | 1 |
| 12 | Fate of biuret 15N and its effect on net mineralisation of native soil n in forest soils 显示文摘 | XUE J M CLINTON P W SANDS R | 2008 | Australian Journal of Soil Research2008，46，： | 1 |
| 13 | Prospective,randomized,double-blind study of the efficacy and tolerability of the extended-release formulations of oxybutynin and tolterodine for overactive bladder; results of the OPERA trial显示文摘 | Diokno A C Apell R A Sand P K | 2003 | Mayo Clin Proc2003，78，4： | 1 |
| 14 | Long-term follow-up of cancer patients receiving radiotherapy for bone metastases:results from a randomised multicentre trial显示文摘 | Sande TA Ruenes R Lund JA | | 0，，02： | 1 |
| 15 | Off Axis Telescope-the Future Generation of Earth Observation Telescopes显示文摘 | H J JURANEK R SAND J SCHWEIZER | 1998 | SPIE1998，3439，： | 1 |
| 16 | Sulfur chemistry, biofilm and (in)direct attack mechanism-a critical evaluation of bacterial leaching显示文摘 | Gerke T Hallmann R | 1995 | Appl Microbiol Biotechnol1995，43，： | 1 |
| 17 | Colorectal high-grade adenomas: incidence, localization and adenoma-adenocarcinoma ratio in a retrospective and comparative population-based study of 225 consecutive cases between 1988 and 1996 显示文摘 | Scheiden R Sand J Pandin M | 1988 | Int J Colorectal Di1988，，： | 1 |
| 18 | 显示文摘 | Ramesh R Gilchrist H Sands T | 1993 | Appl Phys Lett1993，63，： | 1 |
| 19 | Modeling the Impact of Alternative Drainage Practices in the Northern Corn-belt with DRAINMOD-NII显示文摘 | Luo W G R Sands M Youssef | | 0，，03： | 1 |
| 20 | 显示文摘 | Ramesh R Gilchrist H Sands T | 1993 | Appl Phys Lett1993，63，26： | 1 |
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