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| 1 | Comparison of visual acuity, refractive results and complications of femtosecond laser with mechanical microkeratome in LASIK显示文摘AIM: To compare the outcomes of laser in situ keratomileusis (LASIK) performed with a femtosecond laser (Femtec, Technolas Perfect Vision GmbH, Germany) versus a mechanical microkeratome (Hansatome, Bausch and Lomb, USA) for the correction of myopia and astigmatism. ·METHODS: In this retrospective study, patients who had undergone LASIK using the 80 -kHz Femtec femtosecond laser were compared to age- and refraction- matched patients in whom the Hansatome microkeratome was used. Refractive and visual results 1 month and 3 months postoperatively, and complication rates were compared between the two groups. ·RESULTS: A total of 280 eyes were analyzed (140 in each group). At 3 months postoperatively in the Femtec vs Hansatome group, spherical equivalent refraction was within ±1.00D of emmetropia in 140 vs 138 eyes (P = 0.498), the cylinder was within ±0.50D in 137 vs 139 eyes (P =0.622), and the UDVA was 20/20 or better in 136 vs 137 eyes (P =0.724), respectively. There was no statistically significant difference in the complication rates between the two groups (P =0.099). ·CONCLUSION: LASIK performed both with Femtec femtosecond laser and Hansatome microkeratome achieved satisfactory refractive and visual results at 3 months postoperatively, without significant differences in efficacy, safety, and complication rates between the two procedures. | Cemile Banu Cosar Tansu Gonen Murat Moray Asim Bozkurt Sener | 2013 | International Journal of Ophthalmology(English edition)2013，6，3： | 7 |
| 2 | Motility-based label-free detection of parasites in bodily fluids using holographic speckle analysis and deep learning显示文摘Parasitic infections constitute a major global public health issue.Existing screening methods that are based on manual microscopic examination often struggle to provide sufficient volumetric throughput and sensitivity to facilitate early diagnosis.Here,we demonstrate a motility-based label-free computational imaging platform to rapidly detect motile parasites in optically dense bodily fluids by utilizing the locomotion of the parasites as a specific biomarker and endogenous contrast mechanism.Based on this principle,a cost-effective and mobile instrument,which rapidly screens~3.2 mL of fluid sample in three dimensions,was built to automatically detect and count motile microorganisms using their holographic time-lapse speckle patterns.We demonstrate the capabilities of our platform by detecting trypanosomes,which are motile protozoan parasites,with various species that cause deadly diseases affecting millions of people worldwide.Using a holographic speckle analysis algorithm combined with deep learningbased classification,we demonstrate sensitive and label-free detection of trypanosomes within spiked whole blood and artificial cerebrospinal fluid(CSF)samples,achieving a limit of detection of ten trypanosomes per mL of whole blood(~five-fold better than the current state-of-the-art parasitological method)and three trypanosomes per mL of CSF.We further demonstrate that this platform can be applied to detect other motile parasites by imaging Trichomonas vaginalis,the causative agent of trichomoniasis,which affects 275 million people worldwide.With its costeffective,portable design and rapid screening time,this unique platform has the potential to be applied for sensitive and timely diagnosis of neglected tropical diseases caused by motile parasites and other parasitic infections in resource-limited regions. | Yibo Zhang Hatice Ceylan Koydemir Michelle M.Shimogawa Sener Yalcin Alexander Guziak Tairan Liu Ilker Oguz Yujia Huang Bijie Bai Yilin Luo Yi Luo Zhensong Wei Hongda Wang Vittorio Bianco Bohan Zhang Rohan Nadkarni Kent Hill Aydogan Ozcan | 2018 | Light(Science & Applications)2018，7，1： | 6 |
| 3 | Phytochemical screening and free radical scavenging activity of Citrullus colocynthis seeds extracts显示文摘Objective:To study the phytochemical screening of different extracts from Citrullus colocynthis(C.colocynthis)seeds extracts and to assess their antioxidant activity on the DPPH free radical scavenging.Methods:Phytochemical screening,total content of polyphenols and flavonoids of C.colocynthis seeds extracts,including a crude aqueous extract(E1),a defatted aqueous extract(E2),a hydromethanolic extract(HM),an ethyl acetate extract(EA)and a n-butanol extract(n-B)was carried out according to the standard methods and to assess their corresponding effect on the antioxidant activity of this plant.Results:None of these extracts contained detectable amount of alkaloid,quinone,antraquinone,or reducing sugar.Catechic tannins and flavonoids were abundant in E1,MM and EA,whilst terpenoids were abundantly present in E1 and n-B but only weekly in HM.Coumarins were found in E2,EA and n-B.Polyphenols,expressed as gallic acid equivalent,amounted,per 100 g plant matter,to 329,1002 and 150 mg in EA,HM an E1 respectively.Flavonoids,expressed as catechin equivalent,amounted.per 100 g plant matter to 620,241 and 94 mg in EA,HM and E1 respectively.Comparable values were found in n-B and E1,with lower values in E2.Quercetin,myricetin and gallic acid were found in the EA and HM extracts by thin layer chromatography,The antioxidative effect of these extracts yielded,when tested at a concentration of 2000μg/mL in a 1,1-diphenyl-2-picrylhydrazyl assay,a reducing percentage of 88.8%with EA,74.5%with HM and 66.2%with E1,and corresponding IC_(50)of 350,580and 500μg/mL as compared to 1.1μg/mL for ascorbic acid.Conclusions:These qualitative and quantitative analytical data document the presence in C.colocynthis extracts of such chemical compounds as flavonoids responsible for the antioxidant activity,as well as other biological activities of this plant. | Nabila Benariba Rabeh Djaziri Wafaa Bellakhdar Nacera Belkacem Marcel Kadiata Willy J.Malaisse Abdullah Sener | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，1： | 3 |
| 4 | Clinical risk factors for the development of consecutive exotropia:a comparative clinical study显示文摘AIM: To compare a group of patients with consecutive exotropia with patients who had ≤10 prism diopters(PD)esotropia or no deviation postoperatively in terms of probable clinical risk factors for the development of consecutive exotropia.METHODS: The study recruited fourteen patients who developed consecutive exodeviation during follow-up period after the correction of esotropia who were categorized as group 1 and thirty-one patients who had still ≤10 PD esotropia or no deviation at the final visit that were considered as group 2. Clinical risk factors leading the development of consecutive deviation were analyzed as the main outcome measures.RESULTS: The mean age of patients was 4.57±3.11 y in group 1 and 5.10±3.52 y in group 2(P =0.634). There was no significant difference of preoperative near and distant deviations among two groups(P =0.835, 0.928respectively). The mean amount of medial rectus recession and lateral rectus resection was similar in both groups(P =0.412, 0.648 respectively). Convergence insufficiency and neurological diseases were more frequent in group 1(P =0.007, 0.045). Accompanying neurological disease was found to be as a significant factor increasing the risk of the development of consecutive exotropia significantly [odds ratios(OR):5.75(1.04-31.93)]. CONCLUSION: Accompanying neurological disease appears to be a significant clinical risk factor for the development of consecutive exodeviation during postoperative follow-up after the correction of esotropia.However, larger studies are needed in order to interpret the results to the clinical practice and to ascertain other concurrent risk factors. | Hande Tayla Sekeroglu Kadriye Erkan Turan Jale Karakaya Emin Cumhur Sener Ali Sefik Sanac | 2016 | International Journal of Ophthalmology(English edition)2016，9，6： | 2 |
| 5 | 锂辉石:巨型花岗伟晶岩锂-铯-钽矿床中关键含锂矿物显示文摘寻找传统化石燃料的替代能源已成为全球性议题。受动力电池消费的拉动,锂资源需求急剧上升,伟晶岩型锂矿勘查热度持续攀升。虽然众多伟晶岩型锂矿地质特征尚不清晰,已有证据表明锂辉石是大多数大型-巨型伟晶岩型锂矿床的主要含锂矿物。与许多近直立的伟晶岩脉群不同,世界范围内大多数太古代伟晶岩矿脉往往呈近水平或缓倾斜在角闪岩相围岩中产出,它们往往具有复杂的三维形态并发育明显的矿物和地球化学分带。这些太古代伟晶岩脉通常形成于挤压或压剪构造体制下同变质环境中,成岩期最小主应力(σ;)近竖直。因此,伟晶岩常常侵位于近水平的构造局部引张区而形成复杂的几何学形态。压性的构造环境为富锂熔体多次脉动式注入和富含挥发分熔体垂向结晶分异提供了充足的时间;锂辉石在中高温压条件下结晶成为缓倾富锂带中最为常见的含锂矿物。 | GROVES DI 张良 GROVES IM SENER AK | 2022 | 岩石学报2022，38，1： | 2 |
| 6 | Subacute sclerosing panencephalitis findings at MR imaging,diffusion MR imaging, and proton MR spectroscopy 显示文摘 | Sener RN | 2004 | Am J Neuroradiol2004，25，5： | 1 |
| 7 | Identification of KIF21A mutations as a rare cause of congenital fibrosis of the extraocular muscles type 3 ( CFEOM3 ) 显示文摘 | Yamada K Chan WM Andrews C Bosley TM Sener EC Zwaan JT | 2004 | Invest Ophthalmol Vis Sci2004，45，7： | 1 |
| 8 | Preteim prematurerupture of membranes and neonatal outcome prior to 34weeks of gestation显示文摘 | Tanir HM Sener T Tekiu N | 2009 | Int J Gynecol Obstet2009，82，2： | 1 |
| 9 | A micromethod for the assay of aldose reductase, its application to pancreatic islets 显示文摘 | Dufrane S P Malaisse W J Sener A | 1984 | Biochem Med1984，32，1： | 1 |
| 10 | Hemodynamic responses and upper airway morbidity following tracheal intubation in patients with hypertension: conventional Iaryngoscopy versus An intubating Iaryngesl mssk airway显示文摘 | Sener EB Ustun E Ustun B | 2012 | Clinics (Sao Paulo)2012，67，1： | 1 |
| 11 | Bum-induced oxidative injury of the gut is ameliorated by the leukotriene receptor blocker montelukast 显示文摘 | KABASAKAL L SENER G CETINEL S | 2005 | Prostaglandins Leukot Essent Fatty Acids2005，72，6： | 1 |
| 12 | Comparison of percutaneous nephrolithotomy, shock wave lithotrip- sy, and retrograde intrarenal surgery for lower pole re- nal calculi 10-20 mm显示文摘 | Ozturk U Sener N C Goktug H N | 2013 | Urol Int2013，91，3： | 1 |
| 13 | Ketamine with and without midazolam for emergency department sedation in adults:a randomized controlled trial显示文摘 | Sener S Eken C Schultz CH | 2011 | Annals of Emergency Medicine2011，57，10： | 1 |
| 14 | Steel-plate composite walls:experimental database and design for out-of-plane shear显示文摘 | Sener K C Varma A H | 2014 | Journal of Constructional Steel Research2014，100，19： | 1 |
| 15 | Comparative Fatty Acid Analysis of Telekia Speciosa 显示文摘 | Orhan I Sener B | 2003 | Chemistry of Natural Compounds2003，，3： | 1 |
| 16 | L-carnitine ameliorates methotrexate-induced oxidative organ injury and inhibits leukocyte death显示文摘 | SENER G EK S IO GLU-DEMIRALP E CETINER M | | Cell Biology and Toxicology0，，1： | 1 |
| 17 | Long-term patency of sequential and in- dividual saphenous vein coronary bypass grafts 显示文摘 | Kerem M Sener E Tasdemir O | 2001 | Eur J Cardiovasc Surg2001，19，2： | 1 |
| 18 | A Clay-Shoveler's fracture with renal transplantation and osteoporosis:a case report显示文摘 | Unay K Karatoprak O Sener N | 2008 | J Med Case Rep2008，2，6： | 1 |
| 19 | Operative manage- ment of type HI extension supracondylar fractures in children显示文摘 | Kazimglu C Cetin M Sener M | 2009 | Int Orthop2009，，33： | 1 |
| 20 | Steel-plate composite(SC)walls for safety related nuclear facilities:Design for in-plane forces and out-of-plane moments显示文摘 | Varma A H Malushte S R Sener K C | 2014 | Nuclear Engineering and Design2014，269，24： | 1 |
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