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| 1 | Delaying surgery after neoadjuvant chemoradiotherapy improves prognosis of rectal cancer显示文摘AIM To investigate the prognostic effect of a delayed interval between neoadjuvant chemoradiotherapy(CRT) and surgery in locally advanced rectal cancer.METHODS We evaluated 87 patients with locally advanced mid-or distal rectal cancer undergoing total mesorectal excision following an interval period after neoadjuvant CRT at ?i?li Hamidiye Etfal Training and Research Hospital,Istanbul between January 2009 and January 2014.Patients were divided into two groups according to the intervalbefore surgery: < 8 wk(group Ⅰ) and ≥ 8 wk(group Ⅱ).Data related to patients,cancer characteristics and pathological examination were collected and analyzed.RESULTS When the distribution of timing between group Ⅰ(n = 45) and group Ⅱ(n = 42) was viewed,comparison of interval periods(median ± SD) of groups showed a significant difference of as 5 ± 1.28 wk in group Ⅰ and 10.1 ± 2.2 wk in group Ⅱ(P < 0.001).The median follow-up period for all patients was 34.5(9.9-81) mo.group Ⅱ had significantly higher rates of pathological complete response(p CR) than group Ⅰ had(19% vs 8.9%,P = 0.002).Rate of tumor regression grade(TRG) poor response was 44.4% in group Ⅰ and 9.5% in group Ⅱ(P < 0.002).A poor pathological response was associated with worse disease-free survival(P = 0.009).The interval time did not show any association with local recurrence(P = 0.79).CONCLUSION Delaying the neoadjuvant CRT-surgery interval may provide nodal down-staging,improve p CR rate,and decrease the rate of TRG poor response. | Mehmet Mihmanli Esin Kabul Gürbulak Ismail Ethem Akgün Mustafa Fevzi Celayir Pinar Yazici Deniz Tuncel Tuba Tülin Bek Ayhan Oz Sinan Omeroglu | 2016 | World Journal of Gastrointestinal Oncology2016,8,9: | 3 |
| 2 | Determinants and definition of abdominal obesity as related to risk of diabetes, metabolic syndrome and coronary disease in Turkish men: A prospective cohort study显示文摘 | Altan Onat Hüseyin Uyarel Gülay Hergen? Ahmet Karabulut Sinan Albayrak Günay Can | 2006 | Atherosclerosis2006,,1: | 2 |
| 3 | The association betweenserum uric acid level and coronary artery disease显示文摘 | Sinan DO Kabakci G Okutucu S | 2010 | Int J Clin Pract2010,64,7: | 1 |
| 4 | The associatiorr between serum uric acid level and coronary artery disease显示文摘 | Sinan Deveci O Kabakci G Okutucu S | | 0,,07: | 1 |
| 5 | Mechanical properties and microstructure of composites produced by recycling metal chips显示文摘In this study, the processing and mechanical properties of porous metal matrix composites(MMCs) composed of spheroidal cast iron chips(GGG40) and bronze chips(CuSn10) and formed by hot isostatic pressing were investigated. Bronze chips(CuSn10) were used as a matrix component, and spheroidal cast iron(GGG40) chips were used as a reinforcement component. The MMCs were produced with different CuSn10 contents(90 wt%, 80 wt%, 70 wt%, and 60 wt%). The hot isostatic pressing process was performed under three different pressures and temperatures. The produced MMCs were characterized using density tests, Brinell hardness tests, and compression tests. In addition, the consolidation mechanism was investigated by X-ray diffraction(XRD) analysis and scanning electron microscopy. The test results were compared with those for bulk CuSn10 and bulk GGG40. Mechanical tests results revealed that the metallic chips can be recycled by using hot pressing and that the mechanical properties of the produced MMCs were similar to those of bulk CuSn10. XRD and microscopy studies showed that no intermetallic compounds formed between the metallic chips. The results showed that the CuSn10 and GGG40 chips were consolidated by mechanical interlocking. | Abdullah Aslan Aydin Günes Emin Salur Omer Sinan Shin Hakan Burak Karadag Ahmet Akdemir | 2018 | International Journal of Minerals,Metallurgy and Materials2018,25,9: | 1 |
| 6 | The association be- tween serum uric acid level and coronary artery disease 显示文摘 | Sinan Deveci O Kabakci G Okutucu S | 2010 | Interna- tional journal of clinical practice2010,64,7: | 1 |
| 7 | The association between serum uric acid level and coronary artery disease显示文摘 | Sinan Deveci O Kabakci G Okutucu S | 2010 | Intern J Clin Pract2010,64,7: | 1 |
| 8 | The association be- tween serum uric acid level and corollary artery disease显示文摘 | Sinan Deveei 0 Kabakei G Okutueu S | 2010 | Im J Clin Praet2010,64,7: | 1 |
| 9 | The association between serum uric acid level and coronary artery disease显示文摘 | Sinan Deveci O Kabakci G Okulucu S | 2010 | lnt J Clin Praet2010,64,7: | 1 |
| 10 | The association between serum uric acid level and coronary artery disease显示文摘 | Sinan Deveci O Kabakci G Okutucu S | 2010 | Int J Clin Pract2010,64,7: | 1 |
| 11 | The association between serum uric acid level and coronary artery disease显示文摘 | Sinan Deveci O Kabakci G Okutucu S | 2010 | Int J Clin Pract2010,64,7: | 1 |
| 12 | An Extended 10-Core Transrectal Ultrasonography Guided Prostate Biopsy Protocol Improves the Detection of Prostate Cancer显示文摘 | Saadettin Yilmaz Eskicorapci Dilek Ertoy Baydar Cem Akbal Mustafa Sofikerim Mert Günay Sinan Ekici Haluk Ozen | 2003 | European Urology2003,,4: | 1 |
| 13 | The association between serum uric acid level and coronary artery disease显示文摘 | Sinan DO Kabakci G Okutucu S | 2010 | Int J Clin Pract2010,64,7: | 1 |
| 14 | The association between serum uric acid level and coronary artery disease显示文摘 | Sinan Deveci O Kabakci G Okutucu S | 2010 | Int J Clin Pract2010,64,7: | 1 |
| 15 | Current treatment of testicular sex cord-stromal tumors: critical review 显示文摘 | Cenk A Serhat G Sinan S | 2009 | Urology2009,73,: | 1 |
| 16 | The association between serum uric acid level and coronary artery disease 显示文摘 | Sinan Deveci O Kabakci G Okutucu S | 2010 | Int J Clin Pract2010,64,7: | 1 |
| 17 | Changes in IGF-I, IGFBP-3 and ghrelin levels after adenotonsillectomy in children with sleep disordered breathing 显示文摘 | Murat G Q m e ssoya Sinan Atmacaa Birsen Bilgicib Re- cep Q nala | 2009 | International Journal of Pediatric Otorhinolaryngology2009,73,12: | 1 |
| 18 | The association between serum uric acid level and coronary artery disease显示文摘 | Sinan DO Kabakci G Okutucu S | 2010 | lnt J Clin Pract2010,64,7: | 1 |
| 19 | The association between sel31m uric acid level and coronary artery disease 显示文摘 | Sinan Deveei O Kabakci G Okutucu S | 2010 | Int J Clin Pract2010,64,7: | 1 |
| 20 | The association between serum uric acid level and coronary artery disease显示文摘 | Sinan Deveci O Kabakci G Okutucu S | 2010 | International Journal of Clinical Practice2010,64,7: | 1 |