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| 1 | Is toxoplasmosis a potential risk factor for liver cirrhosis?显示文摘Objective:To document Toxoplasma gondii(T.gondii) antibody status in patients with liver disease,blood samples were taken from 180 hepatic patients and 180 healthy controls.Methods:Toxoplasma IgG antibody was detected using enzyme-linked immunosorbent assay and histopathological assessment of liver biopsy METAVIR score was applied.Results:Anti-T.gondii IgG antibodies were found in 32.8%of patients and in 22.2%of controls(P=0.02).Toxoplasma seropositivity was significantly associated with lymphadenopathy,history of blood transfusion and reflex impairment in patients.Chronic hepatitis C virus(HCV)and chronic HCV-related cirrhosis groups compared to chronic HBV and chronic HBV-related cirrhosis groups expressed significantly higher prevalence of T.gondii seropositivity(odds ratio(OR) =4;95%confidence interval(CI):1.3-12.6;P=0.013,OR=4.8;95%CI:1.5-14.9;P=0.006,respectively).Within the chronic HCV group,T.gondii seropositivity significantly associated disease evolution as regards to METAVIR histopathological system for fibrosis and inflammation(OR=19.4;95%CI:2.3-165.2;P=0.0008,OR=0.29;95%CI:0.1-0.8;P=0.01,respectively).Albumin,international normalized ratio(INR) and platelets count were the laboratory parameters significantly altered in Toxoplasma-positrvc chronic HCV patients(P=0.00 l,0.03,0.04,respectively).Child-Pugh scoring for cirrhosis in chronic HCV group placed the majority of seropositive patient in class C with significant statistical difference compared to Child A reference group(OR= 0.08;95%67:0.01-0.5;P=0.003).Conclusions:Toxoplasma seropositivity was high in patients with cirrhosis and associated higher grades of inflammation and necrosis signifying disease evolution,suggesting that cirrhotic patients may thus form a risk group for toxoplasmosis. | Abeer Abd El-Rehim El-Henawy Ahmed Abdel-Razik Sahar Zakaria Dina Elhammady Niveen Saudy Manar Sobh Azab | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，10： | 4 |
| 2 | Label-free SARS-CoV-2 detection and classification using phase imaging with computational specificity显示文摘Efforts to mitigate the COVID-19 crisis revealed that fast,accurate,and scalable testing is crucial for curbing the current impact and that of future pandemics.We propose an optical method for directly imaging unlabeled viral particles and using deep learning for detection and classification.An ultrasensitive interferometric method was used to image four virus types with nanoscale optical path-length sensitivity.Pairing these data with fluorescence images for ground truth,we trained semantic segmentation models based on U-Net,a particular type of convolutional neural network.The trained network was applied to classify the viruses from the interferometric images only,containing simultaneously SARS-CoV-2,H1N1(influenza-A virus),HAdV(adenovirus),and ZIKV(Zika virus).Remarkably,due to the nanoscale sensitivity in the input data,the neural network was able to identify SARS-CoV-2 vs.the other viruses with 96%accuracy.The inference time for each image is 60 ms,on a common graphic-processing unit.This approach of directly imaging unlabeled viral particles may provide an extremely fast test,of less than a minute per patient.As the imaging instrument operates on regular glass slides,we envision this method as potentially testing on patient breath condensates.The necessary high throughput can be achieved by translating concepts from digital pathology,where a microscope can scan hundreds of slides automatically. | Neha Goswami Yuchen R.He Yu-Heng Deng Chamteut Oh Nahil Sobh Enrique Valera Rashid Bashir Nahed Ismail Hyunjoon Kong Thanh H.Nguyen Catherine Best-Popescu Gabriel Popescu | 2021 | Light(Science & Applications)2021，10，9： | 3 |
| 3 | FPGA-Based Network Traffic Security: Design and Implementation Using C5.0 Decision Tree Classifier显示文摘In this work,a hardware intrusion detection system(IDS)model and its implementation are introduced to perform online real-time traffic monitoring and analysis.The introduced system gathers some advantages of many IDSs:hardware based from implementation point of view,network based from system type point of view,and anomaly detection from detection approach point of view.In addition,it can detect most of network attacks,such as denial of services(DoS),leakage,etc.from detection behavior point of view and can detect both internal and external intruders from intruder type point of view.Gathering these features in one IDS system gives lots of strengths and advantages of the work.The system is implemented by using field programmable gate array(FPGA),giving a more advantages to the system.A C5.0 decision tree classifier is used as inference engine to the system and gives a high detection ratio of 99.93%. | Tarek Salah Sobh Mohamed Ibrahiem Amer | 2013 | Journal of Electronic Science and Technology2013，11，4： | 2 |
| 4 | The exposure to cadmium, lead and mercury from smoking and its impact on renal integrity 显示文摘 | Mortada W I Sobh M A E1-Defrawy M M | 2004 | Med Sci Monit2004，10，3： | 1 |
| 5 | Performance improvements on the network security protocols显示文摘 | Sobh T S Elgohary A Zaki M | 2008 | International Journal of Network Security2008，6，1： | 1 |
| 6 | Wired and wireless intrusion detection system:classification,good characteristics and state-of-the-art显示文摘 | Sobh T S | 2006 | Computer Standard & Interfaces2006，28，6： | 1 |
| 7 | Living -related -donor kidney transplantation outcome in recipients with primary focal - seg mental glomerulosclerosis 显示文摘 | Refaie A Sobh M Mousfafa F | 1999 | Am J Nephrol1999，19，1： | 1 |
| 8 | Impact of donor age on living related donor kidney transplantation 显示文摘 | Sobh M E1-Salam YA Shokeir A | 1992 | Transpl Int1992，5，1： | 1 |
| 9 | Living- related - donor kidney transplantation outcome in recipients with primary focalsegment glom Crulosclerosis显示文摘 | REFAIE A SOBH M MOUSTAFA F | 1999 | Am J Nephrol1999，19，： | 1 |
| 10 | Serotyping ofhepatitis C virus in hem odialysis patients:com parison with a standardized genotyping assay显示文摘 | Elsawy EM Sobh M A EL-ChenawiFA | 2005 | Diagn M icrobiolInfec Dis2005，51，2： | 1 |
| 11 | Living-related-donor kidney transplantation outcome in recipients with primary focal-segmental glomerulosclerosis显示文摘 | Refaie A Sobh M Moustafa F | 1999 | Am J Nephrol1999，19，1： | 1 |
| 12 | Immunodiagnosis of prune dwarf virus using antiserum produced to its recombi- nant coat protein显示文摘 | Abou - Jawdah Y Sobh H Cordahi N | 2004 | Journal of Virolgical Methods2004，121，： | 1 |
| 13 | The effect of extracorporeal high blood flow rate on left ventricular function during hemodialysis-an echocardigraphic study显示文摘 | Alfurayh O Galal O Sobh M | 1993 | Clin Cardiol1993，16，： | 1 |
| 14 | Oxidation characteristics of electrodeposlted nickel-zireonia composites at high temperature显示文摘 | Ramesh Bapu G N K Jayakrishnan Sobhe | 2006 | Materials Chemistry and Physics2006，96，23： | 1 |
| 15 | Ofbaxis quanti- tative phase imaging processing using CUDA: toward real-time applications 显示文摘 | Pham H Ding H F Sobh N etal | 2011 | Biomedical Optics Ex- press2011，2，7： | 1 |
| 16 | Production of Antibody Against Ochratoxin A显示文摘 | Chu FS Dowd PF Sobh MA | 1976 | Appl Environ Microbiol1976，31，： | 1 |
| 17 | Living-related-donor kidney transplantation outcome in recipients with primary focal -segmental glomerulosclerosis显示文摘 | Refaie A Sobh M Moustafa F | 1999 | Am J Nephrol1999，19，1： | 1 |
| 18 | Study of lead exposure from automobile exhaust as a risk for nephrotoxicity among traffic policemen显示文摘 | MORTADA W I SOBH M A EI-DEFRAWY M M | 2001 | Am J Nephrol2001，21，4： | 1 |
| 19 | The impact of HLA matc- hing on long-term transplant outcome after allogeneic hematopoietic stem cell transplantation for CLL: a retrospective study from the EB- MT registry显示文摘 | Michallet M Sobh M Million D | 2010 | Leukemia2010，24，0： | 1 |
| 20 | Living related donor kidney t ransplantation outcome in recipients with primary focal segmental glmerulosclerosis显示文摘 | Refaie A Sobh M Moustafa F | 1999 | Am J Nephrolm1999，19，： | 1 |
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