|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017，9，7： | 11 |
| 2 | Mycophenolate mofetil for maintenance of remission in steroid-dependent autoimmune pancreatitis显示文摘Systemic corticosteroids represent the standard treatment for autoimmune pancreatitis with IgG4-associated cholangitis.For steroid-dependent disease,azathioprine has been used for maintenance of remission.Mycophenolate mofetil has been used for transplant immunosuppression and more recently for autoimmune hepatitis;however,there are no case reports to date on the use of mycophenolate mofetil in adult patients with autoimmune pancreatitis.A patient with IgG4-mediated autoimmune pancreatitis and IgG4-associated cholangitis refractory to steroids and intolerant of azathioprine was treated with mycophenolate mofetil,which inhibits de novo guanosine synthesis and blockade of both B and T lymphocyte production.Introduction of mycophenolate mofetil and uptitration to 1000 mg by mouth twice daily over a treatment period of 4 mo was associated with improvement in the patient's energy level and blood glucose control and was not associated with any adverse events.The patient was managed without a biliary stent.However,there was a return of symptoms,jaundice,increase in transaminases,and hyperbilirubinemia when the prednisone dose reached 11 mg per day.In the first report of mycophenolate mofetil use in an adult patient with IgG4-associated autoimmune pancreatitis and IgG4-associated cholangitis,the introduction of mycophenolate mofetil was safe and well-tolerated without adverse events,but it did not enable discontinuation of the steroids.Mycophenolate mofetil and other immunomodulatory therapies should continue to be studied for maintenance of remission in the large subset of patients with refractory or recurrent autoimmune pancreatitis. | Jamie B Sodikoff Steven A Keilin Sheila J Bharmal Melinda M Lewis Gottumukkala S Raju Field F Willingham | 2012 | World Journal of Gastroenterology2012，18，18： | 6 |
| 3 | Floral dip:a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana显示文摘 | Steven J C Andrew F B | 1998 | Plant J1998，16，6： | 1 |
| 4 | Dephosphorylation of Focal Adhesion Kinase (FAK) and Loss of Focal Contacts Precede Caspase-mediated Cleavage of FAK During Apoptosis in Renal Epithelial Cells显示文摘 | van de WATER B NAGELKERKE J F STEVENS J L | 1999 | J Biol Chem1999，274，13： | 1 |
| 5 | Prenylflavonoid variation in Humulus lupulus: distribution and taxonomic significance of xanthogalenol and 4 '-O- metbylxantbobumol 显示文摘 | Stevens J F Taylor A W Nickerson G B | 2000 | Phytochemistry2000，53，： | 1 |
| 6 | Boron isotope evidence for the involvement of non-marine evaporites in the origin of the Broken Hills ore deposits 显示文摘 | Palmer M R Stevens B P J | 1989 | Nature1989，342，： | 1 |
| 7 | Effect of stacking sequence on micro-cracking in a cryogenically cycled carbon/ bismaleimide composite 显示文摘 | Bethel V T Mark B F Steven L D | 2003 | Composites: Part A2003，34，7： | 1 |
| 8 | Origin and significance of tourmaline-rich rocks in the Broken Hills district,Australia 显示文摘 | Palmer M R Stevens B P J | 1994 | Econ Geol1994，88，： | 1 |
| 9 | Community resilience as a metaphor, theory, set of capacities, and strategy for disaster readiness显示文摘 | Norris F Stevens S Pfefferbaum B | 2007 | American Journal of Community Psychology2007，41，12： | 1 |
| 10 | Copyright Protection for the Electronic Distribution of Text Documents显示文摘 | Jack T B Steven L Nicholas F M | 1999 | Proceedings of the IEEE1999，87，7： | 1 |
| 11 | Modu-lation of macrophage and B cell function by glycosaminoglycans显示文摘 | WRENSHALL L E STEVENS R B CERRA F B | 1999 | J Leukoc Biol1999，66，3： | 1 |
| 12 | Vitamin C conjugates of genotoxie lipid peroxide tion products: Structural characterization and de- tection in human plasma显示文摘 | Sowell J Frei B Stevens J F | 2004 | PNAS2004，101，17： | 1 |
| 13 | Interpretation of landscape pattern and habitat change for local indicator species using satellite imagery and geographic information system data in New Brunswick,Canada显示文摘 | MATTHEW G B STEVEN E F | 2003 | Canadian Journal of Forest Re- search2003，33，18： | 1 |
| 14 | Suppession of acoustic noise in speech using spectral subtraction 显示文摘 | Steven F B | 1979 | IEEE Trans on ASSP1979，27，2： | 1 |
| 15 | Community Resilience as a Metaphor, Theory, Set of Capacities, and Strategy for Disaster Readiness显示文摘 | Norris F H Stevens S P Pfefferbaum B Wyche K F Pfe{-ferhaum R L | 2008 | A- merican Journal of Community Psychology2008，41，12： | 1 |
| 16 | Prenylfavonoid variation in Humulus lupulus: distribution and taxonomic significance of xanthogalenol and 4'-O-methylxanthohumol显示文摘 | Stevens J F Taylor A W Niekerson G B | 2000 | Phytochemistry2000，53，7： | 1 |
| 17 | Kangaroo care is effective in diminishing pain response in preterm neonates 显示文摘 | Johnston CC Stevens B Pinelli J Gibbins S Filion F Jack A | 2003 | Arch Pediatr Adolesc Med2003，157，11： | 1 |
| 18 | Antibody response to yersinia pestis flantigen expressed in Salmonella typhimurium aroA from in vivo-inducible promoters 显示文摘 | Helen L B Kate F G Steven M J | 2000 | Vaccine2000，，18： | 1 |
| 19 | Experimental hypothermia and rewarming:Changes in mechanical function and metabolism of tat heart显示文摘 | Steven M F Michael S H Michael J B | 1996 | J Appl physiool1996，80，5： | 1 |
| 20 | Methods of protecting buried pipelines and culverts in transportation infrastructure using EPS geofoam显示文摘 | Steven F B Bret N L Jan V | 2015 | Geotextiles and Geomembranes2015，43，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员