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87篇 您的检索式：作者名="Svestka"

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	题名	作者	年代	出处	被引量
1	Osteopontin: A non-invasive parameter of portal hypertension and prognostic marker of cirrhosis显示文摘AIM: To investigate the relationship between osteopontin plasma concentrations and the severity of portal hypertension and to assess osteopontin prognostic value.METHODS: A cohort of 154 patients with confirmed liver cirrhosis(112 ethylic, 108 men, age 34-72 years)were enrolled in the study. Hepatic venous pressure gradient(HVPG) measurement and laboratory and ultrasound examinations were carried out for all patients. HVPG was measured using a standard catheterization method with the balloon wedge technique. Osteopontin was measured using the enzyme-linked immunosorbent assay(ELISA) method in plasma. Patients were followed up with a specific focus on mortality. The control group consisted of 137 healthy age- and sex- matched individuals.RESULTS: The mean value of HVPG was 16.18 ± 5.6 mm Hg. Compared to controls, the plasma levels of osteopontin in cirrhotic patients were significantly higher(P < 0.001). The plasma levels of osteopontin were positively related to HVPG(P = 0.0022, r = 0.25) and differed among the individual Child-Pugh groups of patients. The cut-off value of 80 ng/m L osteopontin distinguished patients with significant portal hypertension(HVPG above 10 mm Hg) at 75% sensitivity and 63% specificity. The mean follow-up of patients was 3.7 ± 2.6 years. The probability of cumulative survival was 39% for patients with HVPG > 10 mm Hg and 65% for those with HVPG ≤ 10 mm Hg(P = 0.0086, odds ratio(OR), 2.92, 95% confidence interval(CI): 1.09-7.76). Osteopontin showed a similar prognostic value to HVPG. Patients with osteopontin values above 80 ng/m L had significantly lower cumulative survival compared to those with osteopontin ≤ 80 ng/m L(37% vs 56%, P = 0.00035; OR = 2.23, 95%CI: 1.06-4.68).CONCLUSION: Osteopontin is a non-invasive parameter of portal hypertension that distinguishes patients with clinically significant portal hypertension. It is a strong prognostic factor for survival.	Radan Bruha Marie Jachymova Jaromir Petrtyl Karel Dvorak Martin Lenicek Petr Urbanek Tomislav Svestka Libor Vitek	2016	World Journal of Gastroenterology2016，22，12：	20
2	Probabilistic roadmaps for path planning in high-dimensional configuration spaces 显示文摘	Kavraki L E Svestka P Latombe J C	1996	IEEE Transactions on Robotics and Automation1996，12，4：	1
3	Coordinated path planning for multiple robots 显示文摘	P Svestka M H Overmars	1998	Robotics and Autonomous Systems1998，23，3：	1
4	Probabi- listic roadmaps for path planning in high-dimensional configuration spaces 显示文摘	Kavraki L E Svestka P Latombe J C	1996	Robotics and Automation IEEE Transactions on1996，12，4：	1
5	Treatment of acute agitation in psychotic disorders 显示文摘	MOHR P PECENAK J SVESTKA J	2005	Neuro Endocrinol Lett2005，26，4：	1
6	Probabilistic roadmaps for path planning in high-dimensional configuration spaces显示文摘	Kavraki L E Svestka P Latombe J-C	1996	IEEE Trans on Robotics and Automation1996，12，4：	1
7	Probabilistic roadmaps for path planning in high-dimensional configuration spaces 显示文摘	Kavraki L E Svestka P Latombe J C	1996	IEEE Trans on Robotics and Automation1996，12，4：	1
8	Computational experience with an msalesman Jraveling salesman algorithm 显示文摘	Svestka J A Huekfeldt V E	1973	Management Science1973，19，7：	1
9	Probabilistic roadmaps for path planning in high-dimensional configuration spaces显示文摘	Kavraki L Svestka P Latombe J C	1996	IEEE Trans on Robotics and Automation1996，12，4：	1
10	Probabilistic roadmaps for path planning in high-dimensional configuration spaces 显示文摘	Kavraki L Svestka P Latombe J	1996	IEEE Transaction on Robotics and Automation1996，12，4：	1
11	Probabilistic roadmaps for path planning in highdimensional configuration spaces显示文摘	Kavraki L Svestka P Latombe J Overmars M	1996	IEEE Transaction on Robotics and Automation1996，12，4：	1
12	Rescheduling Job Shops under random disruptions显示文摘	ABUMAIZAR R SVESTKA J	1997	International Journal of Production Research1997，35，7：	1
13	Probabilistic Road Maps for Path Planning in High-dimensional Configuration Spaces显示文摘	Kavraki L Svestka P Latombe J C	1996	IEEE Trans on Robotics and Automation1996，12，4：	1
14	Probabilistic Roadmaps for Path Planning in High- Dimensional Configuration Spaces 显示文摘	Kavraki L E Svestka P Latombe J C	1996	IEEE Trans Robot Automat1996，41，4：	1
15	Probabilistic roadmaps for path planning in high - dimensional configuration spaces显示文摘	Kavraki L E Svestka P Latombe J C	1996	IEEE Transactions on Robotics and Automation1996，12，4：	1
16	Treatment of acute agitation in psychotic disorders显示文摘	Pecenák J Svestka J	2005	Neuro Endocrinology Letters[Neuro Endocrinol Lett]2005，26，4：	1
17	Probabilistic Roadmaps for Path Planning in High-Dimensional Configuration Spaces显示文摘	L E Kavraki P Svestka J C Latombe	1996	IEEE Transactions on Robotics and Automation1996，12，4：	1
18	Coordinated path planning for multiple robots显示文摘	SVESTKA P OVERMARS M H	1998	Robotics and Autonomous Systems1998，23，3：	1
19	Rescheduling job shops under random disruptions 显示文摘	Abumaizar R J Svestka J A	1997	International Journal Production Research1997，35，7：	1
20	Probabilistic roadmaps for path planning in high-dimensional configuration spaces显示文摘	Kavraki L E Svestka P Latombe J C	1996	IEEE Transactions on Robotics and Automation1996，12，4：	1

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