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| 1 | Streptococcus agalactiae:Identification methods,antimicrobial susceptibility, and resistance genes in pregnant women显示文摘BACKGROUND Group B Streptococcus(GBS)is a normal component of the gastrointestinal and genital microbiota in humans and can lead to important infections in newborns.AIM To compare GBS isolation and identification methods as well as to assess the antibiotic susceptibility and to identify resistance genes in GBS strains from pregnant women attended in healthcare services from the city of Vitória da Conquista,in Bahia State,Brazil.METHODS From January 2017 to February 2018,vaginorectal swabs were obtained from 186 participants and the samples were seeded onto chromogenic agar for GBS before and after inoculation in selective broth.Confirmatory identification using 3 CAMP and latex tests was performed in samples with GBS-suggestive colonies.Then,disk diffusion antibiograms were performed in GBS-positive samples,and the detection of the resistance genes ermB,ermTR,mefA,and linB in the clindamycin and/or erythromycin-resistant samples was carried out.RESULTS Thirty-two samples(17.2%)were GBS-positive.The culture in chromogenic agar after sample incubation in selective broth was the most sensitive method(96.9%)for GBS detection.All isolates were susceptible to penicillin,ampicillin,cefotaxime,and vancomycin.Clindamycin resistance was observed in 6 samples(18.8%),while 8 samples(25%)were erythromycin-resistant.All erythromycin and/or clindamycin-resistant GBS strains had negative D-tests.Two strains(25%)presented an M phenotype and 6 isolates(75%)presented a cMLSB phenotype.The ermB gene was identified in 4 samples(44.4%),the mefA gene was also found in 4 samples(44.4%),the ermTR gene was identified in 1 isolate(11.1%),and the linB gene was not found in any isolate.CONCLUSION This study evidenced that the screening for SGB can be performed by means of various methods,including chromogenic media,and that the chemoprophylaxis for pregnant women who cannot use penicillin must be susceptibility-guided. | Fabrícia Almeida Fernandes Santana Tais Viana Ledo de Oliveira Marcelo Barreto de Souza Filho Lucas Santana Coelho da Silva Breno Bittencourt de Brito Fabrício Freire de Melo Cláudio Lima Souza Lucas Miranda Marques Márcio Vasconcelos Oliveira | 2020 | World Journal of Clinical Cases2020，8，18： | 2 |
| 2 | Antibiotic Resistance in Salmonella Isolates from Imported Chicken Carcasses in Bhutan and from Pig Carcasses in Vietnam显示文摘 | Ellerbroek L Narapati D Tai N Phu Poosaran N Pinthong R Sirimalaisuwan A Tshering P Fries R Zessin K-h Baumann M Schroeter A | 2010 | Journal of Food Protection2010，，2： | 2 |
| 3 | 星形胶质细胞转录组分析指导的脑卒中靶标鉴定显示文摘星形胶质细胞支持正常的脑功能,但在卒中等病理条件下,星形胶质细胞反应性激活,其也可能参与神经退行性改变。反应性星形胶质细胞增生对机体有益或有害,与环境背景有关,但其分子基础仍未得到充分解释。借助RiboTag技术,我们在特异性地短暂性大脑中动脉闭塞(tMCAO)72h后的小鼠星形胶质细胞中,纯化翻译mRNA,构建卒中特异性星形胶质细胞翻译组数据库。我们发现,与对照组脑组织相比,tMCAO后的反应性星形胶质细胞显示与A2表型相关的转录物的富集,这与神经保护相关。星形胶质细胞也会上调大量潜在的神经毒性基因。我们共鉴定了1003个基因和38个转录因子的差异表达,其中Stat3,Sp1和Spi1变化最明显。为了进一步探索Stat3介导的通路对卒中发病机制的影响,我们选择星形胶质细胞特异性条件性缺失Stat3的小鼠制造tMCAO模型,发现这些小鼠的局灶性缺血卒中体积减少,且梗死72h后小鼠的运动结果改善。综上所述,本研究扩展了新兴的星形胶质细胞特异性靶向卒中治疗数据库,并肯定了星形胶质细胞是脑功能的关键保障细胞。 | Rakers C Schleif M Blank N Matu?ková H Ulas T H?ndler K Torres SV Schumacher T Tai K Schultze JL Jackson WS Petzold GC 聂昊 | 2019 | 神经损伤与功能重建2019，14，6： | 2 |
| 4 | A binary level set model and some applications to mumford-shah image segmentation 显示文摘 | L/E J LYSAKER M TAI X C | 2006 | IEEE Transactions on Image Processing2006，15，1： | 1 |
| 5 | The quality and size of yolk sac in early pregnancy loss显示文摘 | CHOFN CHEN SN TAI M H | 2006 | Aust N Z J Obstet Gynaecol2006，46，5： | 1 |
| 6 | Overexpression of VEGF is associated with positive p53 immunostaining in hepatocellular carcinoma (HCC) and adverse outcome of HCC patients显示文摘 | TSENG P L TAI M H HUANG C C | 2008 | J Surg Oncol2008，98，5： | 1 |
| 7 | The stereochemistry of 3-hydroxy-2- methylbutyric acid显示文摘 | Tai A Imaida M | 1978 | B Chem Soc JPN1978，51，4： | 1 |
| 8 | Optimalclinical timelines-a consensus from the academic department ofmilitary surgery and trauma显示文摘 | Tai NR Brooks A Midwinter M Clasper JC Parker PJ | 2009 | J R Army Med Corps2009，155，4： | 1 |
| 9 | Characterization of gap junctional intercellular communication in immortalized human pancreatic ductal epithelial cells with stem cell characteristics显示文摘 | Tai M H Olson L K Madhukar B V et ai | 2003 | Pancreas2003，26，： | 1 |
| 10 | Transduction of Lac-Z gene into leukemia cells using viral vectors of adenovirus and retrovirus显示文摘 | Tai M Lin T Hibio H | 1995 | Leukemia1995，9，1： | 1 |
| 11 | Fabrication and mechanical properties of multi walled carbon nanotubes/epoxy nano composites 显示文摘 | Yeh M K Hsieh T H Tai N | 2008 | Mater Sci Eng A2008，483，484： | 1 |
| 12 | Clinical experience of StarClose vascular closure device in patients with first and recurrent femoral punctures显示文摘 | Tay EL Co M Tai BC | 2008 | J Interv Cardiol2008，21，1： | 1 |
| 13 | Chrysoeriol isolated from the leaves of Eurya ciliata stimulates proliferation and differentiation of osteoblastic MC3T3- E1 cells 显示文摘 | Tai B H Cuong N M Huong T T | 2009 | JAsian Nat Prod Res2009，11，9： | 1 |
| 14 | HIV increases HCV replication in a TGF-β1-Dependent manner 显示文摘 | Lin W Y Weinberg E M Tai A W | 2008 | Gastroenterrology2008，134，： | 1 |
| 15 | Noise Removal Using Fourth-Order Partial Differential Equation with Applications to Medical Magnetic Resonance Images in Space and Time 显示文摘 | Lysaker M Lundervold A Tai X C | 2003 | IEEE Trans on Image Processing2003，12，12： | 1 |
| 16 | Treatmentof postoperative pain in oral and maxillofacial sur2gery显示文摘 | Coulthard P Haywood D Tai M A | 2000 | Br J OralMaxillofac surgery2000，38，： | 1 |
| 17 | Modeling and control of steering sys- tem of heavy vehicles for automated highway systems 显示文摘 | Tai M Hingwe P | 2004 | IEEE Transactions on Mechatronics2004，9，5： | 1 |
| 18 | Identification and characterization of phenylpyruvate decarboxylase genes in Saccharomyces cerevisiae显示文摘 | VURALHAN Z MORAIS M A TAI S L | 2003 | Applied and Environmental Microbiology2003，69，8： | 1 |
| 19 | Reaffirmation of GAK,but not HLA-DRA,as a Parkinson's disease susceptibility gene in a Taiwanese population显示文摘 | Lin C H Chen M L Tai Y C | | 0，，： | 1 |
| 20 | Pullout strength of pedicle screws with cement augmentation in severe osteoparosis:a comparative study between cannulated screws with cement injection and solid screws with cement pre-filling 显示文摘 | Chen LH Tai CL Lee DM et M | 2011 | BMC Museuloskelet Disord2011，12，： | 1 |
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