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353篇 您的检索式：作者名="THOME M"

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	题名	作者	年代	出处	被引量
1	Involvement of autophagy in alcoholic liver injury and hepatitis C pathogenesis显示文摘This review describes the principal pathways of macroautophagy (i.e. autophagy), microautophagy and chaperone-mediated autophagy as they are currently known to occur in mammalian cells. Because of its crucial role as an accessory digestive organ, the liver has a particularly robust autophagic activity that is sensitive to changes in plasma and dietary components. Ethanol consumption causes major changes in hepatic protein and lipid metabolism and both are regulated by autophagy, which is significantly affected by hepatic ethanol metabolism. Ethanol exposure enhances autophagosome formation in liver cells, but suppresses lysosome function. Excessive ethanol consumption synergizes with hepatitis C virus (HCV) to exacerbate liver injury, as alcohol-consuming HCV patients frequently have a longer course of infection and more severe manifestations of chronic hepatitis than abstinent HCV patients. Alcohol-elicited exacerbation of HCV infection pathogenesis is related to modulation by ethanol metabolism of HCV replication. Additionally, as part of this mechanism, autophagic proteins have been shown to regulate viral (HCV) replication and their intracel-lular accumulation. Because ethanol induces autophagosome expression, enhanced levels of autophagic proteins may enhance HCV infectivity in liver cells of alcoholics and heavy drinkers.	Natalia A Osna Paul G Thomes Terrence M Donohue	2011	World Journal of Gastroenterology2011，17，20：	5
2	Inhibition of death receptor signals by cellular FLIP显示文摘	Irmler M Thome M Hahne M	1997	Nature1997，388，6638：	1
3	The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex显示文摘	Micheau o Thome M Schneider P	2002	J Biol Chem2002，277，45：	1
4	The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex显示文摘	Micheau O Thome M Schneider P	2002	J Biol Chemistry2002，277，45：	1
5	Inhibition of death receptor signals bycelluar FLIP显示文摘	Irmler M Thome M Hahne M	1997	Nature1997，388，6638：	1
6	Inhibition of fas death signals by FLIPs显示文摘	Tschopp J Irmler M Thome M	1998	Curr Opin Immunol1998，10，：	1
7	Falling-film evaporation on tube bundle with plain and enhanced tubes - Part I: Experimental results显示文摘	Habert M Thome J R	2010	Experimental Heat Transfer2010，23，4：	1
8	Riverbank stability analysis I: Theory 显示文摘	OSMAN A M THOME C R	1988	Journal of Hydraulic Engineering1988，114，2：	1
9	Prediction of two-phasepressure gradients of refrigerants in horizontal tubes显示文摘	Ould Didi M B Kattan N Thome J R	2002	International Journal of Refrigeration2002，25，7：	1
10	Riverbank stability analysis II : Application 显示文摘	THOME C R OAMAN A M	1988	Journal of Hydraulic Engineering1988，114，15：	1
11	Determination of precipitable water from solar transmission显示文摘	Thome K J Herman B M Reagan J A	1992	J Appl Meteor1992，31，：	1
12	Part I:presentation of the model显示文摘	Thome J R Dupont V Jacobi A M Heat transfer model for evaporation in microchannels	2004	Int J Heat Mass Transfer2004，47，1416：	1
13	Inhibition of death receptor signals by cellular FLIP 显示文摘	Irmler M Thome M Hahne M	1997	Nature1997，388，6638：	1
14	Characterization of two receptors for TRAIL显示文摘	Bodmer JL Thome M	1997	FEBS Lett1997，416，3：	1
15	CARMAl,BCL10 and MALT1 in lymphocyte development and activation显示文摘	Thome M	2004	Nat Rev Immunol2004，4，5：	1
16	Cardioprotective ac- tivity of Cladosiphon okamuranus against isoproterenol induced myocardial infraction in rats显示文摘	Thomes P Rajendran M Pasanban B	2010	Phytomedicine2010，18，1：	1
17	The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex显示文摘	Micheau O Thome M Schneider P	2002	J Biol Chem2002，277，45：	1
18	Phosphorylation of CARMA1:the link(er)to NF-kappa B activation显示文摘	Rueda D Thome M	2005	Immunity2005，23，6：	1
19	Radiosonde temperature trends and their uncertainties over easte-rn China显示文摘	Guo Yanjun Thome P W McCarthy M P	2008	Int J Climatol2008，28，：	1
20	Determination of precipitable water from solar transmission 显示文摘	Thome K J Herman B M Reagan J A	1992	J Appl Meteor1992，31，：	1

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