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| 1 | Transdermal delivery of 4-aminopyridine accelerates motor functional recovery and improves nerve morphology following sciatic nerve crush injury in mice显示文摘Oral 4-aminopyridine(4-AP)is clinically used for symptomatic relief in multiple sclerosis and we recently demonstrated that systemic 4-AP had previously unknown clinically-relevant effects after traumatic peripheral nerve injury including the promotion of re-myelination,improvement of nerve conductivity,and acceleration of functional recovery.We hypothesized that,instead of oral or injection administration,transdermal 4-AP(TD-4-AP)could also improve functional recovery after traumatic peripheral nerve injury.Mice with surgical traumatic peripheral nerve injury received TD-4AP or vehicle alone and were examined for skin permeability,pharmacokinetics,functional,electrophysiological,and nerve morphological properties.4-AP showed linear pharmacokinetics and the maximum plasma 4-AP concentrations were proportional to TD-4-AP dose.While a single dose of TD-4-AP administration demonstrated rapid transient improvement in motor function,chronic TD-4-AP treatment significantly improved motor function and nerve conduction and these effects were associated with fewer degenerating axons and thicker myelin sheaths than those from vehicle controls.These findings provide direct evidence for the potential transdermal applicability of 4-AP and demonstrate that 4-AP delivered through the skin can enhance in-vivo functional recovery and nerve conduction while decreasing axonal degeneration.The animal experiments were approved by the University Committee on Animal Research(UCAR)at the University of Rochester(UCAR-2009-019)on March 31,2017. | Andrew RClark Chia George Hsu M A Hassan Talukder Mark Noble John CElfar | 2020 | Neural Regeneration Research2020，15，1： | 3 |
| 2 | Atmospheric pressure gliding arc discharge plasma treatments for improving germination, growth and yield of wheat显示文摘Wheat(Triticum aestivum) seeds were treated with atmospheric pressure gliding arc discharge plasmas to investigate the effects on water absorption, seed germination rate, seedling growth and yield in wheat. The surface architectures and functionalities of the seeds were found to modify due to plasma treatments. 6 min treatment was provided 95%–100% germination rate.For the treatment duration of 3 and 9 min the growth activity, dry matter accumulation, leaves chlorophyll contents, longest spikes, number of spikes/spikelet and total soluble protein content in shoots were improved. The grain yield of wheat was increased ~20% by 6 min treatment with H_2O/O_2 plasma with respect to control. | N C ROY M M HASAN A H KABIR M A REZA M R TALUKDER A N CHOWDHURY | 2018 | Plasma Science and Technology2018，20，11： | 2 |
| 3 | Improved method for efficient production of biodiesel from palm oil显示文摘 | RAHMAN TALUKDER M M MIN BEATRICE K L PUAY SONG O PUAH S CHUAN WU J JAE WON C CHOW Y | 2008 | Energy Fuels2008，22，1： | 1 |
| 4 | Targeting calcium transport in isehaemic heart disease显示文摘 | Hassan Talukder M A Zweier J L Periasamy M | 2009 | Car Res2009，84，3： | 1 |
| 5 | Synthesis and the preliminary analysis of block copolymers of 3,3′-bis(azidomethyl)-oxetane and 3-nitratomethyl-3- methyloxetane 显示文摘 | Talukder M A H Lindsay G A | 1990 | Journal of Polymer Science Part A: Polymer Chemistry1990，28，9： | 1 |
| 6 | Effect of short-term heat stress prior to flowering and at early grain set on the utilization of water-soluble carbohydrate by wheat genotypes显示文摘 | Talukder A S M H M Mcdonald G K Gill G S | 2013 | Field Crops Research2013，14，7： | 1 |
| 7 | Enzymatic production of biodiesel from Jatropha oil : A comparative study of immobihzed-whole cell and commercial hpases as a biocatalyst 显示文摘 | Tamalampudi S Talukder M R Hama S | 2008 | Biochemical Engineering Journal2008，39，1： | 1 |
| 8 | Targeting calcium transport in ischaemic heart disease显示文摘 | Talukder MA Zweier JL Periasamy M | 2009 | Cardiovasc Res2009，84，3： | 1 |
| 9 | Targeting calcium transport in ischaemic heart disease显示文摘 | Talukder MA Zweier JL Periasamy M | 2009 | Cardiovaac Res2009，84，3： | 1 |
| 10 | Ultrasonication Enhanced Hydrolytic Activity of Lipase in Water/ Isooctane Two-Phase Systems 显示文摘 | Talukder M M R Zaman M M Hayashi Y | 2006 | Biocatalysis and Biotransformation2006，24，3： | 1 |
| 11 | An improved method of lipase preparation incorporating both solvent treatment and immobilization onto matrix显示文摘 | TALUKDER M R M SRIAPPAREDDY T LI C J | 2007 | Biochemical Engineering Journal2007，33，： | 1 |
| 12 | An improved method of lipase preparation incorporating both solvent treatment and immobilization onto matrix 显示文摘 | Md Talukder M R Tamalampudy S Li C J | 2007 | Biochem Eng J2007，33，： | 1 |
| 13 | Phenotypic and genotypic characterization of serologically atypical strains of shigeUaflexneri type 4 isolated in dhaka, Bangladesh显示文摘 | TALUKDER K A ISLAM M A DUTTA D K | 2002 | J Clin Microbiol2002，40，24： | 1 |
| 14 | Pneumatic hammer in an extemaUy pressurized orifice-compensated air journal bearing 显示文摘 | Talukder H M Stowell T B | 2003 | Tribol Int2003，36，8： | 1 |
| 15 | MTA1 interacts with MAT1, a cyclin-dependent kinase- activating kinase complex ring finger factor, and regulates estrogen receptor transactivation functions 显示文摘 | Talukder AH Mishra SK Mandal M | 2003 | J Biol Chem2003，278，11： | 1 |
| 16 | Pneumatic hammer in an externally pressurized orifice-compensated air journal bearing显示文摘 | TALUKDER H M STOWELL T B | 2003 | Tribology International2003，36，8： | 1 |
| 17 | Activity of acetone-treated Chromobacterium viscosum lipase in AOT reverse rni- celles in the presence of low molecular weight polyethylene glycol显示文摘 | ZAMAN M M HAYASHI Y TALUKDER M M R | 2006 | Biochem Eng J2006，29，12： | 1 |
| 18 | Structural characteristics of heparin-line domain required for interaction of midkine with embryonic neurons显示文摘 | Kaneda N Talukder A H Ishihara M | 1996 | Biochem Biophys Res Commun1996，220，1： | 1 |
| 19 | Effect of the pretreatment of lipase with organic solvents on its conformation and activity in reverse micelles 显示文摘 | Moniruzzaman M Talukder M R Hayashi Y | 2007 | Appl Biochem Biotechnol2007，142，3： | 1 |
| 20 | Pneumatic hammer in an externally pressurized orifice-compensated air journal beating显示文摘 | TALUKDER H M STOWELL T B | 2003 | Tribology International2003，36，8： | 1 |
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