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| 1 | Proteome analysis of hepatocellular carcinoma by laser capture microdissection显示文摘 | Ai J Tan Y Ying W Hong Y Liu S Wu M Qian X Wang H | 2006 | 第二军医大学学报2006,27,5: | 14 |
| 2 | Polymorphisms of MTHFD,plasma homocysteine levels, and risk of gastric cancer in ahigh-risk Chinese population显示文摘Purpose:Accumulative evidence suggests that folate has a protective effect on gastric cancer. The methylenetetrahyd-rofolate dlehydrogenase(MTHFD) plays an important role in folate and homocysteine metabolisms, and polymorphisms of MTHFD may result in disturbance of the folate-mediated homocysteine pathway. The aim of this study is to test the hypothesis that genetic variants of MTHFD and plasma homocysteine levels are associated with risk of gastric cancer and modulated by genotypes of methylenetetrahydrofolate reductase(MTHFR). Experimental Design: We genotyped G1958A and T401C in MTHFD and C677T in MTHFR and detected total plasma homocysteine(tHcy) levels in a case-control study of 589 gastric cancer cases and 635 cancer-free controls in a high-risk Chinese population. Results:The variant genotypes of MTHFD 1958AA and 401CC were associated with a significantly increased risk of gastric canceradjusted odds ratio(OR), 2.05; 95% confidence interval(95% CI),1.34-3.13 for 1958AA; adjusted OR,1.43; 95% CI,1.14-1.80 for 401CC compared with 1958GG/GA and 401TT/TC genotypes, respectively. Both of the effects were more evident in the subjects carrying MTHFR 677CT/TT genotypes. The average tHcy level was significantly higher in gastric cancer cases than in controls(P < 0.01), and the upper quartile of tHcy (> 13.6 mu mol/L) was associated with an 82% significantly increased risk of gastric cancer, compared with the lowest quartile of tHcy(<= 8.0 pmol/L;adjusted OR,1.82; 95% CI,1.20-2.75). Conclusions:The strong associations between MTHFD variants and the plasma tHcy levels and gastric cancer risk suggest, for the first time, a possible gene-environment interaction between genetic variants of folate-metabolizing genes and high tHcy levels in gastric carcinogenesis. | Wang, L. N Ke, Q Chen, W. S Wang, J. M Tan, Y. F Zhou, Y Hua, Z. L Ding, W. L Niu, J. Y Shen, J Zhang, Z. F Wang, X. R Xu, Y. H Shen, H. B Yi Xing | 2007 | 南京医科大学学报(自然科学版)2007,27,7: | 10 |
| 3 | 2018—2019年度中国医务人员流感疫苗接种情况网络调查显示文摘中国医务人员流感疫苗接种率较低,为了促进医务人员接种流感疫苗,2018年10月国家卫生健康委员会要求医院要为医务人员免费提供流感疫苗接种。为了解2018—2019年度医务人员流感疫苗接种情况及可能的影响因素,该研究利用丁香园注册医务人员进行抽样调查,共调查了4078名医务人员。 | 谭亚运(编译) Liu H Tan Y Zhang M | 2020 | 中华预防医学杂志2020,54,2: | 6 |
| 4 | In vitro Ruminal Gas Production Kinetics of Four Fodder Trees Ensiled With or Without Molasses and Urea显示文摘This study investigated if the addition of urea (U), molasses (M) or their 1:1 (v/v) mixture during ensiling increases the nutritional value of forage from four fodder trees (Prunus persica, Leucaena esculenta, Acacia farnesiana, and Prunus domestica). Forage samples of fodder trees were collected in triplicate (three individual samples of each species) and subjected to an in vitro gas production (GP) procedure. Fermentation at 24 h (GP 24), short-chain volatile fatty acids (SCFA), and microbial crude protein production (MCP), in vitro organic matter digestibility (OMD), metabolizable energy (ME) and dry matter degradability (DMD) were estimated. Forage samples were incubated for 72 h in an incubator at 39oC and the volume of GP was recorded at 2, 4, 6, 8, 10, 12, 24, 48, and 72 h of incubation using the reading pressure technique. The rumen fermentation profiles were highest for P. persica, which showed the highest (P<0.0001) DMD, ME, OMD, SCFA, GP 24 and MCP. On the other hand L. esculenta had the lowest (P<0.0001) DMD, SCFA, MCP; P. domestica had the lowest (P<0.0001) OMD. The addition of M to silage increased (P<0.0001) ME and OMD, as well as GP. However, the addition of U and the mixture of U and M reduced (P<0.0001) DMD, ME, OMD, SCFA, GY 24 and MCP. These results show that P. persica has the highest nutritive value and L. esculenta the lowest for ruminants. Additionally, the addition of M to forage from fodder trees increases rumen GP and fermentation, which may improve nutrient utilization in ruminants. | Abdelfattah Z M Salem ZHOU Chuan-she TAN Zhi-liang Miguel Mellado Moises Cipriano Salazar Mona M M Y Elghandopur Nicholas E Odongo | 2013 | Journal of Integrative Agriculture2013,12,7: | 3 |
| 5 | J Power Sources显示文摘 | Matsuoka O Hiwara A Omi T Toriida M Hayashi T Tanaka C Saito Y Ishida T Tan H Ono S S Yamamoto S | 2002 | 108:1282002,108,: | 1 |
| 6 | P6 aeupoint injec- tion reduce postoperative nausea and vomiting显示文摘 | Shyr M H Hsu J C Wu Y W Hui Y L Tan P P | 1990 | Ma Tsui Hsueh Tsa Chi Anaesthesiol Sinica1990,28,6: | 1 |
| 7 | Plasma matrix metal- loproteinase-9,tissue inhibitor of metalloproteinase-2,and CD40 ligand levels in patients with stable coronary artery dis- ease显示文摘 | Tayebjee M H Lip G Y Tan K T | 2005 | Am J Cardiol2005,96,3: | 1 |
| 8 | Efficacy of recombinant methioninase in combination with cisplatin on human colon tumors in nude mice显示文摘 | Tan Y Sun X Xu M | 1999 | Clin Cancer Res1999,5,: | 1 |
| 9 | PTGF-beta,a type beta transforming growth factor(TGF-beta) superfamily member,is a p53 target gene that inhibits tumor cell growth via TGF-beta signaling pathway显示文摘 | Tan M Wang Y Guan K | 2000 | Proc Natl Acad Sci USA2000,97,1: | 1 |
| 10 | Overview on fabrication of three-dimensional structures in multi-layer ceramic substrate 显示文摘 | KHOONG L E TAN Y M LAMA Y C | 2010 | Journal of the European Ceramic Society2010,30,19: | 1 |
| 11 | Measured performance of a 26 m deep top-down excavation in downtown Shanghai 显示文摘 | Tan Y Li M W | 2011 | Canadian Geotechnical Journal2011,48,5: | 1 |
| 12 | Timed compatibility analysis of web service composition: A modular approach based on petri nets显示文摘 | Du Y Tan W Zhou M | 2014 | IEEE Transactions on Automation Science and Engineering2014,11,2: | 1 |
| 13 | Drainage efficiency of sand layer in layered clay-sand reclamation 显示文摘 | TAN S A LIANG K M YONG K Y | 1992 | Journal of Geotechnical Engineering ASCE1992,118,2: | 1 |
| 14 | Survival-and death-promoting events after transient cerebral ischemia:phosphrylation of Akt,release of cytochrome C and Activation of caspase-like proteases显示文摘 | TAN Y COMB M | 2005 | J Cereb Blood Flow Metab2005,19,10: | 1 |
| 15 | A fixed-frequency pulsewidth modulation based quasi-sliding-mode controller for Buck converters显示文摘 | TAN S C LAI Y M TSE C K | 2005 | IEEE Transactions on Power Electronics2005,20,6: | 1 |
| 16 | Mapping quantitative trait loci for milling quality,protein content and color characteristics of rice using a recombinant inbred line population derived from an elite rice hybrid显示文摘 | Tan Y F Sun M Xing Y Z | 2001 | Theoretical and Applied Genetics2001,103,: | 1 |
| 17 | Immobilization of glu-cose oxidase on chitosan-SiO2 gel显示文摘 | Yang Y M Wang J W Tan R X | 2004 | Enzyme and Mi-crobial Technology2004,34,2: | 1 |
| 18 | Effect of micro-structural changes on mechanical properties of La66Al14(Cu,Ni)20 amorphous and crystalline alloys显示文摘 | Zhanga Y Lee M L Tan H | 2004 | Intermetallics2004,,: | 1 |
| 19 | Berberine hydmchloride: anticancer ac- tivity and nanopartieulate delivery system显示文摘 | Tan W Li Y Chen M | 2011 | Int J Nanomedicine2011,6,: | 1 |
| 20 | Combustion characteristics of coal in a mixture of oxygen and recycled flue gas显示文摘 | TAN Y CROISET E DOUGLAS M A THAMBIMUTHU K V | 2006 | Fuel2006,85,4: | 1 |