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| 1 | 简易封闭式负压引流治疗35例汶川地震伤员创面的效果分析显示文摘目的探讨简易封闭式负压引流技术治疗地震伤员创面的疗效。方法回顾性分析使用简易封闭式负压引流技术治疗35例汶川地震伤员的临床资料,并与2008年1月1日至5月1日收治的采用常规治疗的同类型患者35例对照,比较治疗效果。结果封闭式负压组伤员经治疗6~12天(平均7.5±1.8天)后,创面达到Ⅱ期闭合条件。创面全部治愈,其中植皮覆盖24处、Ⅱ期缝合4处、局部皮瓣转移修复5处、交腿皮瓣修复2处。与常规治疗比较,两组在Ⅱ期缝合、植皮或皮瓣转移的时间、换药次数及住院时间等方面差异均有统计学意义(P<0.01)。Ⅱ期后续植皮疗效差异也有统计学意义(P<0.05)。结论简易封闭式负压引流技术能缩短创面Ⅱ期处理时间、促进创面愈合、减少换药次数及材料耗费、有利于Ⅱ期所植皮片成活;在紧急情况下,VSD敷料及生物透性薄膜价格昂贵且有限,简易封闭式负压引流技术是一种简单、安全、有效的应急治疗方法,且可降低成本。 | 李永忠 胡晓东 Moris Topaz 李云飞 陈莉 | 2009 | 中国循证医学杂志2009，9，3： | 30 |
| 2 | 封闭式持续负压吸引技术在地震伤创面感染治疗中的应用显示文摘对26例地震伤有伤口创面感染的伤员,采用封闭式持续负压吸引技术治疗3-10天后,Ⅱ期植皮或直接缝合伤口,植皮创面继续封闭式持续负压吸引治疗,创面愈合。封闭式持续负压吸引治疗能加快感染创面坏死组织脱落,减少分泌物,有效控制感染,促进肉芽生长及创面愈合;Ⅱ期植皮创面不需打包加压包扎,可减少伤员换药痛苦,减轻医务人员工作量,减少抗生素等使用,降低截肢率。 | 李永忠 李云飞 Moris Topaz 陈莉 罗典清 李卉丹 | 2008 | 创伤外科杂志2008，10，5： | 8 |
| 3 | Minimizing treatment complexity of combat-related soft tissue injuries using a dedicated tension relief system and negative pressure therapy augmented by high-dose in situ antibiotic therapy and oxygen delivery: a retrospective study显示文摘Background:Following combat-related,extensive soft tissue injury from gunshot wounds or blasts,prolonged duration from injury to full wound closure is associated with infection,increased morbidity and mortality,failure to mobilize,poor functional outcome and increased cost.The purpose of this study was to evaluate a novel treatment enabling early primary closure of combat wounds.Methods:This was a retrospective study of 10 soldiers and civilians with extensive combat-related soft tissue limb injuries(5 gunshot wounds,5 blasts)treated using the TopClosure^(■)Tension Relief System(TRS)with simultaneous administration of regulated oxygen-enriched and irrigation negative pressure-assisted wound therapy(ROINPT)via the Vcareα^(■)device.Results:Nine patients were treated during the acute phase of injury and one was treated following removal of a flap due to deep infection 20 years after injury and flap reconstruction.Two patients had upper limb injury and the rest lower limb injury.With the aid of the TRS and/or ROINPT,immediate primary closure during reconstruction was achieved in 6 patients and delayed primary closure in three.Only one patient required a skin graft to close a small area of the wound after most of the wound had been closed by delayed primary closure.Wound closure was achieved within 0–37 days(median:12.5 days,interquartile range:2.75–19.75)from injury.Conclusions:The TRS is a novel device for effective,early skin stretching and secure wound closure through the application of stress relaxation and mechanical creep,achieving primary closure of large defects using a simplified surgical technique and reducing the need for closure using skin grafts and flaps and the use of tissue expanders.Delivering supplemental oxygen to the wound by ROINPT reverses the reduced oxygen levels inherent in conventional negative pressure-assisted wound therapy,mitigating anaerobic contamination and reducing infection.Irrigation may accelerate the evacuation of infectious material from the wound and provide a novel method for antibiotic administration.The combination of TRS and ROINPT devices allow for early primary closure with improved functionality of combat-related limb injuries. | Moris Topaz Itamar Ashkenazi Oren Barzel Seema Biswas Dan Atar Nurit Shadmi Itzhak Siev-Ner | 2021 | Burns & Trauma2021，9，1： | 7 |
| 4 | 皮肤外扩张器修复巨大创面二例显示文摘由于皮肤软组织扩张器不能用于腹部等皮下无支撑的部位及开放性创面,由此大量相关器械得到一定程度发展,并被广泛应用于临床。2015年肖潇等0报道1例采用皮肤外扩张器修复右颈肩部肿瘤切除的病例,2014年9月至2015年5月,我们应用皮肤外扩张器治疗皮肤软组织巨大创面2例,取得较好的效果。 | 蒋朔 陈莉 李永忠 李云飞 胡晓东 Moris Topaz | 2016 | 中华整形外科杂志2016，32，2： | 4 |
| 5 | 封闭式负压吸引术在地震伤创面治疗中的应用显示文摘目的探讨封闭式持续负压吸引技术在地震伤皮肤或软组织损伤创面的疗效。方法对42例地震伤中有皮肤、软组织损伤及伤口并感染的伤员采用封闭式持续负压吸引治疗,4~12d后,创面二期植皮或直接缝合伤口。结果41例创面肉芽生长新鲜,经植皮或直接缝合后创面愈合,1例因骨骼外露,经钻孔再行持续负压吸引后皮瓣转移覆盖创面。结论封闭式持续负压吸引治疗对于地震伤皮肤或软组织损伤的治疗,具有使用方便,简单有效的优势。 | 李云飞 李永忠 Moris Topaz 罗典清 | 2009 | 西部医学2009，21，2： | 4 |
| 6 | 伤口管理的新技术在重度难愈性伤口处理中的临床应用(英文)显示文摘伤口的感染导致创面修复成为一个复杂和缓慢的过程。伤口闭合时间的长短可以直接影响到创面的感染率、发病率、患者的死亡率、抗生素的使用频率、耐药菌形成的几率和相关的经济消费情况。伤口愈合的越早,感染和瘢痕的形成几率越低。TopClosure@皮肤牵张系统(Top Closure ^(R) tension relief system,TRS)及其可调控伤口内氧含量和可冲洗伤口的负压辅助创面治疗(regulated oxygen—enriched&irrigation negative pressure-assisted wound therapy,ROI—NPT)技术的联合应用,明显缩短了伤口的闭合时间,降低了患者其他药物的使用频率,缩短了患者的住院时间。这种先进的治疗方法的协同应用,为伤口的处理提出了一个全新的概念,优化和改善了伤口的愈合功能,形成了新的伤口治疗和护理标准。 | Moris Topaz 朱占永 赵月强 陈学杰 李爱林 余墨声 | 2016 | 临床外科杂志2016，24，3： | 3 |
| 7 | Application of regulated ox- ygen-enriched negative pressure-assisted wound therapy in combating anaerobic infections; Oxygen-enriched negative pressure treatment 显示文摘 | Topaz M Bisker O Litmanoviteh M | 2011 | European J Plastic Surgery2011，34，5： | 1 |
| 8 | Giant Aneurysms of Coronary Arteries and Saphenous Vein Grafts: Angiographic Findings and Histopathological Correlates显示文摘 | Topaz O Molly S R Shannon M B etal | 2005 | Cardiovascular Pathology2005，14，6： | 1 |
| 9 | Differential effects of prostaglandin E(2)and enamel matrix derivative on the proliferation of human gingival and dermal fibroblasts and gingival keratinocytes显示文摘 | Weinberg E Topaz M Dard M | 2010 | J Periodontal Res2010，45，6： | 1 |
| 10 | Cardio trauma : diagnosis, management, and current therapy 显示文摘 | Olsovsky MR Wechsler AS Topaz O | 1997 | Angiology1997，48，5： | 1 |
| 11 | A substitute for skin grafts, flaps, or internal tissue expanders in scalp defects following tumor ab- lative surgery 显示文摘 | Topaz M Carmel NN Topaz G | 2014 | J Drugs Dermatol2014，13，1： | 1 |
| 12 | Possible longer--term complications in UAL induced by sonoluminescence, sonochemistry, and thermal effect显示文摘 | | 1998 | Aesthetic Surgery Journel1998，18，： | 1 |
| 13 | Cardiac trauma: Diagnosis,management, and current therapy显示文摘 | Olsovsky MR Wechsler AS Topaz O | 1999 | Angiology1999，48，： | 1 |
| 14 | Acute traumatic ventricular septal rupture显示文摘 | Olsovsky MR Topaz O Disciascio G | | 0，，： | 1 |
| 15 | Investigating the challen- ges and opportunities in home care to facilitate effective infor- mation technology adoption显示文摘 | Koru G Alhuwail D Topaz M | 2016 | J Am Med Dir Assoc2016，17，1： | 1 |
| 16 | A deleterious mutation in SAMD9 causes normophosphatemic familial tumoral calcinosis显示文摘 | Topaz O Indelman M Chefetz I | 2006 | Am J Hum Genet2006，79，4： | 1 |
| 17 | Diastolic balloon pumping (with carbon dioxide)in the aorta-A mechanical assistance to the failing circulation 显示文摘 | Moulopolous SD Topaz S Kolff WJ | 1962 | AmHeart J1962，63，： | 1 |
| 18 | 1例皮肤外扩张器整形修复右颈肩部肿瘤切除患者的护理显示文摘皮肤外扩张器(TOP—CLOSER)就是通过外力将创缘两边正常皮肤向中央牵托,利用皮肤弹性、机械伸展性、线性负载循环产生“额外”皮肤,从而闭合创口。本例患者包块切除后创面缺损约40cm×25cm,使用皮肤外扩张器修复,术后3周拆除皮肤外扩张器,伤口I,甲愈合,术后给予放射治疗。随访3个月.切口愈合良好,疤痕不明显,包块无复发。现报道如下。 | 肖潇 李永忠 陈莉 杨文玲 谢珊 Moris Topaz | 2015 | 当代护士(下旬刊)2015，22，1： | 1 |
| 19 | Interventricular septal rupture complicating acute myocardial infarction: from pathophysiologic features to the role of invasive and noninvasive diagnostic modalities in current management 显示文摘 | Topaz O Tayior AL | 1992 | American Journal of Medicine1992，93，6： | 1 |
| 20 | Interventricular septal rupture complicating acute myocardial infarction:from pathophysiologic features to the role of invasive and noninvasive diagnostic modalities in current management显示文摘 | Topaz O Taylor AL | 1992 | Am J Med1992，93，： | 1 |
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