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| 1 | Animal venom studies: Current benefits and future developments显示文摘Poisonous organisms are represented in many taxa, including kingdom Animalia. During evolution, animals have developed special organs for production and injection of venoms. Animal venoms are complex mixtures, compositions of which depend on species producing venom. The most known and studied poisonous terrestrial animals are snakes, scorpions and spiders. Among marine animals, these are jellyfishes, anemones and cone snails. The toxic substances in the venom ofthese animals are mainly of protein and peptide origin. Recent studies have indicated that the single venom may contain up to several hundred different components producing diverse physiological effects. Bites or stings by certain poisonous species result in severe envenomations leading in some cases to death. This raises the problem of bite treatment. The most effective treatment so far is the application of antivenoms. To enhance the effectiveness of such treatments, the knowledge of venom composition is needed. On the other hand, venoms contain substances with unique biological properties, which can be used both in basic science and in clinical applications. The best example of toxin application in basic science is α-bungarotoxin the discovery of which made a big impact on the studies of nicotinic acetylcholine receptor. Today compositions of venom from many species have already been examined. Based on these data, one can conclude that venoms contain a large number of individual components belonging to a limited number of structural types. Often minor changes in the amino acid sequence give rise to new biological properties. Change in the living conditions of poisonous animals lead to alterations in the composition of venoms resulting in appearance of new toxins. At the same time introduction of new methods of proteomics and genomics lead to discoveries of new compounds, which may serve as research tools or as templates for the development of novel drugs. The application of these sensitive and comprehensive methods allows studying either of venoms available in tiny amounts or of low abundant components in already known venoms. | Yuri N Utkin | 2015 | World Journal of Biological Chemistry2015,6,2: | 3 |
| 2 | Transient near tip fields in crack dynamics显示文摘Transient effects of stress-strain fields in the vicinity of a stationary crack tip under high rate loads are discussed.Exact analytical solutions to near tip stresses are compared to fields prescribed by leading terms(one or several) of Williams asymptotic expansion.Influence of load application mode,time(or,which is the same,distance from a crack tip) and Poisson's ratio on this discrepancy is extensively examined.Some effects connected with crack tip propagation speed are also discussed.Significant inconsistencies between real(or received in numerical solutions of state equations-e.g.finite element computations) crack tip fields and stress intensity factor(SIF) singular field observed by numerous researchers are explained.The scope of problems where SIF field can be used for correct prediction of dynamic stress-strain fields in the crack tip region is established.Possibility to correctly approximate fields that are not SIF dominated,accounting additional terms of Williams expansion,is studied. | BRATOV Vladimir PETROV Yuri UTKIN Alexander | 2011 | Science China(Physics,Mechanics & Astronomy)2011,54,7: | 2 |
| 3 | Variable structure systems with sliding modes 显示文摘 | Utkin V I | 1977 | IEEE Transactions on Automatic Control1977,22,2: | 1 |
| 4 | Variable structure systems with sliding modes显示文摘 | Utkin V I | 1977 | IEEE Transactions on Automatic Control1977,22,2: | 1 |
| 5 | Sliding mode control design based on Ackermann's formula显示文摘 | Ackermann J Utkin V | 1998 | IEEE Transactions on Automatic Control1998,43,2: | 1 |
| 6 | Variable structure systems with sliding modes 显示文摘 | Utkin V I | 1977 | IEEE Transactions Automatic Control1977,22,2: | 1 |
| 7 | Contact Strength Estimates of the Reliability of Conical Gears with Limited Statistical Information显示文摘 | V S Utkin | 2010 | Russi- an Engineering Research2010,30,1: | 1 |
| 8 | Sliding mode control design principles and applications to electrical drives显示文摘 | Utkin V I | 1993 | IEEE Trans on Industrial Electronics1993,40,1: | 1 |
| 9 | On the nature of temperature variations in borehole kun- 1 (Kunashir Island)显示文摘 | Demezhko D Yu Yurkov A K Utkin V I | 2012 | Russian Geology and Geophysics2012,53,: | 1 |
| 10 | Variable structure system with sliding modes显示文摘 | Utkin V | 1979 | IEEE Transactions on Automatic and Control1979,22,2: | 1 |
| 11 | A control engineer's guide to sliding mode control显示文摘 | Young K D Utkin V I | 1999 | IEEE Transaction on Control Systems Technology1999,7,3: | 1 |
| 12 | Observer design of critical states for air path flow regulation in a variable geometry turbocharger exhaust gas recirculation diesel engine 显示文摘 | Glenn B C Upadhyay D Utkin V L | 2011 | International Journal of Vehicle Design2011,12,6: | 1 |
| 13 | Variable structure systems with sliding modes显示文摘 | | 1977 | IEEE Transactions on Automatic Control1977,22,: | 1 |
| 14 | On sliding mode observers via equivalent control applouch 显示文摘 | Haskara I Ozguner U Utkin V | 1998 | Int J Control1998,71,6: | 1 |
| 15 | Adherence, anti-adherence, and oligosaccharides preventing pathogens from sticking to the host显示文摘 | Shoaf-Sweeney K D H utkins R W | 2009 | Adv Food Nutr Res2009,55,: | 1 |
| 16 | Variable structure systems with sliding modes显示文摘 | Utkin V I | 1977 | IEEE Transactions Automatic Control1977,22,2: | 1 |
| 17 | On new cautious structural reliability models in the framework of imprecise probabilties显示文摘 | Utkin L V Kozine I | 2010 | Structural Safety2010,32,6: | 1 |
| 18 | Variable structure systems with sliding modes 显示文摘 | V1 UtKin | 1977 | IEEE Transcaction Automatic Control1977,22,2: | 1 |
| 19 | Sliding Mode Control Design Based on Ackermann's Formula显示文摘 | Vadim Utkin | 1998 | IEEE Transactions on Automatic Control1998,43,2: | 1 |
| 20 | Sliding mode control design principles and applications to electric drives显示文摘 | Utkin V I | 1993 | IEEE Transactions on Industrial Electronics1993,40,1: | 1 |