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| 1 | Type 3 innate lymphoid cell-derived lymphotoxin prevents microbiota-dependent inflammation显示文摘Splenomegaly is a well-known phenomenon typically associated with inflammation.However,the underlying cause of this phenotype has not been well characterized.Furthermore,the splenomegaly phenotype seen in lymphotoxin(LT)signaling-deficient mice is characterized by increased numbers of splenocytes and splenic neutrophils.Splenomegaly,as well as the related phenotype of increased lymphocyte counts in non-lymphoid tissues,is thought to result from the absence of secondary lymphoid tissues in LT-deficient mice.We now present evidence that mice deficient in LTα1β2 or LTβR develop splenomegaly and increased numbers of lymphocytes in non-lymphoid tissues in a microbiota-dependent manner.Antibiotic administration to LTα1β2-or LTβR-deficient mice reduces splenomegaly.Furthermore,re-derived germ-free Ltbr−/−mice do not exhibit splenomegaly or increased inflammation in non-lymphoid tissues compared to specific pathogen-free Ltbr−/−mice.By using various LTβ-and LTβR-conditional knockout mice,we demonstrate that retinoic acid-related orphan receptorγT-positive type 3 innate lymphoid cells provide the required active LT signaling to prevent the development of splenomegaly.Thus,this study demonstrates the importance of LT-mediated immune responses for the prevention of splenomegaly and systemic inflammation induced by microbiota. | Yuan Zhang Tae-Jin Kim Joanna A Wroblewska Vera Tesic Vaibhav Upadhyay Ralph R Weichselbaum Alexei V Tumanov Hong Tang Xiaohuan Guo Haidong Tang Yang-Xin Fu | 2018 | Cellular & Molecular Immunology2018，15，7： | 3 |
| 2 | 人工全膝关节置换后股骨假体角度的CT影像学评估:股骨外上髁线参照与间隙平衡技术的对比研究(英文)显示文摘[目的]虽然人工全膝关节置换术中假体旋转定位的重要性已得到公认,但术中以哪条轴线为参照能够更加精确的保证股骨假体的旋转定位,目前尚存争议。研究表明股骨外上髁线(TEA)与膝关节屈曲轴线平行,但这一轴线术中难以精确确定。本文采用间隙平衡技术(BG),对比TEA技术在股骨假体实际旋转角度测量的差异。[方法]30例人工全膝关节置换分为2组(每组15膝),分别采用TEA和BG技术,术后行CT扫描测量股骨假体旋转角度并行膝关节学会评分(KSS)。[结果]BG组中股骨假体平均外旋角度为2.7°±1.1°,TEA组为5.6°±1.6°(P=0.001)。术后KSS功能评分改善BG组高于TEA组(P=0.002),但两组的KSS膝评分无显著性差异(P=0.39)。[结论]研究表明,与BG技术相比,术中应用TEA参照确定股骨假体的旋转定位可导致股骨假体的过度外旋,其术后KSS功能评分亦较差。 | Shrinand V Vaidya Aditya V Maheshwari Rajesh M Gadhiya Vaibhav Bagaria Amar S Ranawat Chitranjan S Ranawat | 2008 | 中国矫形外科杂志2008，16，12： | 2 |
| 3 | Performance of Kenics static mixer over a wide range of Reynolds number 显示文摘 | Kumar V Vaibhav Shirke Nigam K D P | 2008 | Chem Eng J2008，139，2： | 1 |
| 4 | Biodiesel production from re- newable feedstocks: status and opportunities 显示文摘 | VENU B B VAIBHAV V G | 2012 | Renew Sustain Energy Rev2012，16，7： | 1 |
| 5 | Global identification of conserved post-transcriptional regulatory programs in trypanosomatids显示文摘 | Hamed S. Najafabadi Zhiquan Lu Chad MacPherson Vaibhav Mehta Véronique Adoue Tomi Pastinen Reza Salavati | 2013 | Nucleic Acids Research2013，，： | 1 |
| 6 | Production of first and second generation biofuels: A comprehensive review显示文摘 | Naik S N Vaibhav V Goud Prasant K Rout | 2010 | Renewable and Sustainable Energy Reviews2010，14，2： | 1 |
| 7 | Production of first and second generation biofuels : A comprehensive review显示文摘 | Naik S N Vaibhav V Goud Prasant K Rout | 2010 | Renewable and Sustainable Energy Reviews2010，14，2： | 1 |
| 8 | Production of first and second generation biofuels: A comprehensive review显示文摘 | S N Naik Vaibhav V Goud P K Rout | 2010 | Renewable and Sustainable Energy Reviews2010，14，2： | 1 |
| 9 | Production of first and second generation biofuels: A comprehensive review显示文摘 | S N Naik Vaibhav V Goud Prasant K Rout | 2010 | Renewable and Sustainable Energy Reviews2010，14，： | 1 |
| 10 | Biodiesel pro- duction from renewable feedstocks :Status and opportu- nities 显示文摘 | Venu Babu Borugadda Vaibhav V Goud | 2012 | Renewable and Sustainable Energy Reviews2012，16，7： | 1 |
| 11 | Supercritical CO2 fractionation of bio-oil produced from wheat-hemlock biomass显示文摘 | Naik Satyanarayan Goud V Vaibhav Rout K Prasant | 2010 | Bioresource Technology2010，101，19： | 1 |
| 12 | Studies on the epoxidation of mahua oil (Madhumica indica) by hydrogen peroxide 显示文摘 | Vaibhav V G Nanrayan C P Anand V P | 2006 | Bioresource Zechnology2006，97，12： | 1 |
| 13 | Corrosion resistant low temperature carburized SS 316 as bipolar plate material for PEMFC application 显示文摘 | Vaibhav V Nikam Ramana G Reddy Sunniva R Collins | 2008 | Electrochimica Acta2008，53，： | 1 |
| 14 | Production ofFirst and Second Generation Biofiiels ?? A Comprehensive Review显示文摘 | Naik S N Vaibhav V G Prasant K R | 2010 | Renew Sustain Energy Rev2010，14，2： | 1 |
| 15 | Studies on the epoxidation of mahua oil( Madhumica indica) by hydrogen peroxide 显示文摘 | Vaibhav V Goud Anand V Patwardhan Narayan C Pradhan | 2006 | Bioresource Technology2006，97，： | 1 |
| 16 | Epoxidation of canola oil with hydrogen peroxide catalyzed by acidic ion exchange resin显示文摘 | Rubeena M Narayan C P Vaibhav V G | 2008 | J Am Oil Chem Soc2008，85，： | 1 |
| 17 | Studies on the epoxidation of mahua oil(madhumica indica) by hydrogen peroxide显示文摘 | VAIBHAV V G ANAND V P NARAYAN C P | 2006 | Bioresource Technology2006，97，12： | 1 |
| 18 | Ultrasound assisted lime pretreatment of lignocellulosic biomass toward bioethanol production显示文摘 | Sasmal Soumya Goud Vaibhav V Mohanty Kaustubha | | 0，，06： | 1 |
| 19 | Epoxidation of karanja (Pongamia glabra) oil by H2O2显示文摘 | Vaibhav V Goud Narayan C Pradhan Anand V Patwardhan | 2006 | Journal of the American Oil Chemists'' Society2006，83，7： | 1 |
| 20 | Biodiesel production from renewable feedstocks : Status and opportunities 显示文摘 | Venu Babu Borugadda Vaibhav V Goud | 2012 | Renew- able and Sustainable Energy Reviews2012，16，7： | 1 |
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