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| 1 | Current oncologic applications of radiofrequency ablation therapies显示文摘Radiofrequency ablation (RFA) uses high frequency alternating current to heat a volume of tissue around a needle electrode to induce focal coagulative necrosis with minimal injury to surrounding tissues. RFA can be performed via an open, laparoscopic, or image guided percutaneous approach and be performed under general or local anesthesia. Advances in delivery mechanisms, electrode designs, and higher power generators have increased the maximum volume that can be ablated, while maximizing oncological outcomes. In general, RFA is used to control local tumor growth, prevent recurrence, palliate symptoms, and improve survival in a subset of patients that are not candidates for surgical resection. It's equivalence to surgical resection has yet to be proven in large randomized control trials. Currently, the use of RFA has been well described as a primary or adjuvant treatment modality of limited but unresectable hepatocellular carcinoma, liver metastasis, especially colorectal cancer metastases, primary lung tumors, renal cell carcinoma, boney metastasis and osteoid osteomas. The role of RFA in the primary treatment of early stage breast cancer is still evolving. This review will discuss the general features of RFA and outline its role in commonly encountered solid tumors. | Dhruvil R Shah Sari Green Angelina Elliot John P McGahan Vijay P Khatri | 2013 | World Journal of Gastrointestinal Oncology2013，5，4： | 33 |
| 2 | GRADE指南:Ⅶ.证据质量评价--不一致性显示文摘本文针对二分类变量结局指标相对(而非绝对)治疗效果的不一致性。证据本身不会因不同研究结果具有一致性而升级,但可能因不一致而降低质量级别。衡量一致性的标准包括点估计值的相似性、可信区间的重叠程度以及统计学判定标准包括异质性检验和I2。系统评价作者应提出并检验少数几个与患者、干预措施、结局指标以及方法学相关的先验假设以探寻异质性来源。当不一致性很大且无法解释时,因不一致性而降低质量级别是恰当的,特别当某些研究显示有显著益处而其他显示无益甚至有害时(而非仅是疗效大与疗效小的比较)。明显的亚组效应可能不可靠。如果亚组效应满足以下条件,其可信度将会增加:基于少数几个有具体方向的先验假设、亚组比较来自研究内而非研究间、交互检验的P值小、结果有生物学意义。 | Gordon H.Guyatt Andrew D.Oxman Regina Kunz James Woodcock Jan Brozek Mark Helfand Pablo Alonso-Coello Paul Glasziou Roman Jaeschke Elie A.Akl Susan Norris Gunn Vist Philipp Dahm Vijay K.Shukla Julian Higgins Yngve Falck-Ytter Holger J.Schünemann 代表GRADE小组 李幼平 杨晓妍 王莉 蔡羽嘉 陈群飞 | 2011 | 中国循证医学杂志2011，11，12： | 33 |
| 3 | Inflammatory bowel disease and cancer: The role of inflammation, immunosuppression, and cancer treatment显示文摘In patients with inflammatory bowel disease(IBD), chronic inflammation is a major risk factor for the development of gastrointestinal malignancies. The pathogenesis of colitis-associated cancer is distinct from sporadic colorectal carcinoma and the critical molecular mechanisms underlying this process have yet to be elucidated. Patients with IBD have also been shown to be at increased risk of developing extra-intestinal malignancies. Medical therapies that diminish the mucosal inflammatory response represent the foundation of treatment in IBD, and recent evidence supports their introduction earlier in the disease course. However, therapies that alter the immune system, often used for long durations, may also promote carcinogenesis. As the population of patients with IBD grows older, with longer duration of chronic inflammation and longer exposure to immunosuppression, there is an increasing risk of cancer development. Many of these patients will require cancer treatment, including chemotherapy, radiation, hormonal therapy, and surgery. Many patients will require further treatment for their IBD. This review seeks to explore the characteristics and risks of cancer in patients with IBD, and to evaluate the limited data on patients with IBD and cancer, including management of IBD after a diagnosis of cancer, the effects of cancer treatment on IBD, and the effect of IBD and medications for IBD on cancer outcomes. | Jordan E Axelrad Simon Lichtiger Vijay Yajnik | 2016 | World Journal of Gastroenterology2016，22，20： | 33 |
| 4 | Comparison of visual analogue scale (VAS) and the Nasal Obstruction Symptom Evaluation (NOSE) score in evaluation of post septoplasty patients显示文摘Objective:To compare and correlate the efficacy of the NOSE score&the VAS score in determining the symptomatic benefit in patients undergoing septoplasty.Materials and methods:Eighty patients with deviated nasal septum undergoing septoplasty were included in the study.NOSE score&VAS score(out of 100)was documented before and after surgery.Results were correlated and compared statistically.Results:In the NOSE score,the most bothersome symptom was trouble breathing through the nose(85.83);followed by Nasal obstruction or blockage(82.50).Wilcoxon test showed significant improvement with NOSE score and VAS score in all patients at 1 month and 3 months.Spearman’s coefficient showed a positive correlation between the two,though the score improvement and patient satisfaction rate was significantly high with NOSE score.Conclusions:NOSE score and the VAS score both provide effective framework for evaluating treatment responses after septoplasty.However,the NOSE score showed higher improvement and better patient satisfaction rate when used to measure of nasal obstruction as compared to the VAS score. | Radhika Hiren Shukla Sanjana Vijay Nemade Kiran Jaywant Shinde | 2020 | World Journal of Otorhinolaryngology-Head and Neck Surgery2020，6，1： | 28 |
| 5 | Detection of plant leaf diseases using image segmentation and soft computing techniques显示文摘Agricultural productivity is something on which economy highly depends.This is the one of the reasons that disease detection in plants plays an important role in agriculture field,as having disease in plants are quite natural.If proper care is not taken in this area then it causes serious effects on plants and due to which respective product quality,quantity or productivity is affected.For instance a disease named little leaf disease is a hazardous disease found in pine trees in United States.Detection of plant disease through some automatic technique is beneficial as it reduces a large work of monitoring in big farms of crops,and at very early stage itself it detects the symptoms of diseases i.e.when they appear on plant leaves.This paper presents an algorithm for image segmentation technique which is used for automatic detection and classification of plant leaf diseases.It also covers survey on different diseases classification techniques that can be used for plant leaf disease detection.Image segmentation,which is an important aspect for disease detection in plant leaf disease,is done by using genetic algorithm. | Vijai Singh A.K.Misra | 2017 | Information Processing in Agriculture2017，4，1： | 28 |
| 6 | Comparative clinical trial of S-pantoprazole versus racemic pantoprazole in the treatment of gastro-esophageal reflux disease显示文摘AIM: To compare the effi cacy and tolerability of S-pan- toprazole (20 mg once a day) versus racemic Panto- prazole (40 mg once a day) in the treatment of gastro- esophageal reflux disease (GERD). METHODS: This multi-centre, randomized, double-blind clinical trial consisted of 369 patients of either sex suf- fering from GERD. Patients were randomly assigned to receive either one tablet (20 mg) of S-pantoprazole once a day (test group) or 40 mg racemic pantoprazole once a day (reference group) for 28 d. Patients were evaluated for reduction in baseline on d 0, GERD symptom score on d 14 and 28, occurrence of any adverse effect during the course of therapy. Gastrointestinal (GI) endoscopy was performed in 54 patients enrolled at one of the study centers at baseline and on d 28. RESULTS: Signifi cant reduction in the scores (mean and median) for heart burn (P < 0.0001), acid regurgitation (P < 0.0001), bloating (P < 0.0001), nausea (P < 0.0001) and dysphagia (P < 0.001) was achieved in both groups on d 14 with further reduction on continuing the therapy till 28 d. There was a statistically signifi cant difference in the proportion of patients showing improvement in acid regurgitation and bloating on d 14 and 28 (P = 0.004 for acid regurgitation; P = 0.03 for bloating) and heart burn on d 28 (P = 0.01) between the two groups, with a higher proportion in the test group than in the refer- ence group. Absolute risk reductions for heartburn/acid regurgitation/bloating were approximately 15% on d 14 and 10% on d 28. The relative risk reductions were 26%-33% on d 14 and 15% on d 28. GI endoscopy showed no signifi cant difference in healing of esophagitis (P = 1) and gastric erosions (P = 0.27) between the two groups. None of the patients in either group reported any adverse effect during the course of therapy.CONCLUSION: In GERD, S-pantoprazole (20 mg) is more effective than racemic pantoprazole (40 mg) in improving symptoms of heartburn, acid regurgitation, bloating and equally effective in healing esophagitis and gastric erosions. The relative risk reduction is 15%-33%. Both drugs are safe and well tolerated. | Vikas G Pai Nitin V Pai Hemant P Thacker Jaisingh K Shinde Vijay P Mandora Subhash S Erram | 2006 | World Journal of Gastroenterology2006，12，37： | 19 |
| 7 | Total hip replacement for arthritis following tuberculosis of hip显示文摘AIM: To present the results of total hip arthroplasty(THA) for post tubercular arthritis of the hip joint.METHODS: Sixty-five patients(45 male, 20 female) with previously treated tuberculosis of the hip joint underwent cementless THA for post tubercular arthritis. The average age at the time of THA was 48 years(range 29 to 65 years). Erythrocyte sedimentation rate, C reactive protein, chest X-ray and contrast enhanced magnetic resonance imaging were done preoperatively to confirm resolution of the disease and to rule out any residual disease. Intra-operative samples were taken for microbiological examination, polymerase chain reaction(PCR) and histological examination. Patients were started on anti-tubercular drugs one week before the operation and continued for 6 mo post operatively. The patients were followed up clinically using the Harris hip score as well as radiologically for any loosening of the implants, osteolysis and any recurrence of tuberculosis. Any complications especially the recurrence of the infection was also recorded.RESULTS: The mean interval from completion of antitubercular therapy for tuberculosis to surgery was 4.2 years(range, 2-6 years). Preoperatively, 17 patients had ankylosis whereas 48 patients had functional but painful range of motion. The mean surgical time was 97 min(range, 65-125) whereas the mean blood loss was 600 m L(range, 400-900 m L). The average follow up was 8.3 years(range 6-11 years). The average Harris Hip score improved from 27 preoperatively to 91 at the final follow up. Seventeen patients had acetabularprotrusion which was managed with impaction grafting and cementless acetabular cup. The bone graft had consolidated in all these 17 patients at the follow up. Two patients developed discharging sinuses at 9 and 11 mo postoperatively respectively. The discharge tested positive for tuberculosis on the PCR. Both these patients were put on antitubercular therapy for another year. Both of them recovered and had no evidence of any loosening or osteolysis on X-rays. There were no other complications recorded.CONCLUSION: Total hip replacement restores good function to patients suffering from post tubercular arthritis of the hip. | Vijay Kumar Bhavuk Garg Rajesh Malhotra | 2015 | World Journal of Orthopedics2015，6，8： | 19 |
| 8 | Complications in the management of closed high-energy proximal tibial plateau fractures显示文摘 | Kavin Khatri Vijay Sharma Darsh Goyal Kamran Farooque | 2016 | Chinese Journal of Traumatology2016，19，6： | 18 |
| 9 | Imaging evaluation of traumatic thoracolumbar spine injuries: Radiological review显示文摘Spine fractures account for a large portion of musculoskeletal injuries worldwide. A classification of spine fractures is necessary in order to develop a common language for treatment indications and outcomes. Several classification systems have been developed based on injury anatomy or mechanisms of action, but they have demonstrated poor reliability, have yielded little prognostic information, and have not been widely used. For this reason, the Arbeitsgemeinschaftfür Osteosynthesefragen(AO) committee has classified thorocolumbar spine injuries based on the pathomorphological criteria into3 types(A: Compression; B: Distraction; C: Axial torque and rotational deformity). Each of these types is further divided into 3 groups and 3 subgroups reflecting progressive scale of morphological damage and the degree of instability. Because of its highly detailed sub classifications, the AO system has shown limited interobserver variability. It is similar to its predecessors in that it does not incorporate the patient's neurologic status.The need for a reliable, reproducible, clinically relevant, prognostic classification system with an optimal balance of ease of use and detail of injury description contributed to the development of a new classification system, the thoracolumbar injury classification and severity score(TLICS). The TLICS defines injury based on three clinical characteristics: injury morphology, integrity of the posterior ligamentous complex, and neurologic status of the patient. The severity score offers prognostic information and is helpful in decision making about surgical vs nonsurgical management. | Shivanand Gamanagatti Deepak Rathinam Krithika Rangarajan Atin Kumar Kamran Farooque Vijay Sharma | 2015 | World Journal of Radiology2015，7，9： | 18 |
| 10 | Modeling,Control,and Protection of Modular Multilevel Converter-based Multi-terminal HVDC Systems:A Review显示文摘Multi-terminal direct current(MTDC)grids provide the possibility of meshed interconnections between regional power systems and various renewable energy resources to boost supply reliability and economy.The modular multilevel converter(MMC)has become the basic building block for MTDC and DC grids due to its salient features,i.e.,modularity and scalability.Therefore,the MMC-based MTDC systems should be pervasively embedded into the present power system to improve system performance.However,several technical challenges hamper their practical applications and deployment,including modeling,control,and protection of the MMC-MTDC grids.This paper presents a comprehensive investigation and reference in modeling,control,and protection of the MMC-MTDC grids.A general overview of state-of-the-art modeling techniques of the MMC along with their performance in simulation analysis for MTDC applications is provided.A review of control strategies of the MMC-MTDC grids which provide AC system support is presented.State-of-the art protection techniques of the MMCMTDC systems are also investigated.Finally,the associated research challenges and trends are highlighted. | Lei Zhang Yuntao Zou Jicheng Yu Jiangchao Qin Vijay Vittal George G.Karady Di Shi Zhiwei Wang | 2017 | CSEE Journal of Power and Energy Systems2017，3，4： | 17 |
| 11 | Surgical treatment of proximal humerus fractures using PHILOS plate显示文摘ObjectiveTo 与经历了的 51 个病人打开的为近似肱骨 fractures.MethodsWe 的板考察了的近似肱骨的内部锁住系统(PHILOS ) 评估开的减小和内部固定的功能的结果和复杂并发症有在年之间的 PHILOS 板的减小和内部固定 2007 ~ 2012。与 38 的吝啬的年龄有 35 个男人和 16 个女人;年(范围 24-68 ) 。在年龄组有 41 个病人 < 60 在年龄组的年和 10 个病人 > 60 年。根据更旧姓的分类系统, 8, 15 和 23 个病人有 2 部分, 3 部分,和 4 部分破裂,分别地并且 5 个病人让 4 部分断裂脱臼。所有手术在我们的第三级的照顾损伤中心被执行。在最后的后续的肩膀的功能的评估用 Constant-Murley score.ResultsThe 平均数后续被做经期是 30 月(范围 12-44 月) 。二个病人被失去到后续。留下 49 个病人,所有破裂临床上并且放射学地被统一。放射学的联合的吝啬的时间是 12 星期(范围 8-20 星期) 。在最后的后续,吝啬的 Constant-Murley 分数是 79 (范围 50-100 ) 。结果在 25 个病人,是优秀的在 13 个病人好、在 6 个病人公平、在 5 个病人差。在后续期间,内翻足 malunion, subacromial 冲击的一个盒子,深感染的一个盒子, intraarticular 螺丝钉穿入的一个盒子和固定的失败的一个盒子的四个盒子被注意。avascular 坏死的没有盒子,硬件失败,松开的锁住的螺丝钉或不属于工会 noted.ConclusionPHILOS 在近似肱骨破裂提供稳定的固定。为了阻止潜在的复杂并发症,希望 avascular 坏死,保存肱骨的头的由脉管形成的过细的外科的解剖是必要的。 | GN Kiran Kumar Gaurav Sharma Vijay Sharma Vaibhav Jain Kamran Farooque Vivek Morey | 2014 | Chinese Journal of Traumatology2014，17，5： | 14 |
| 12 | Recent Progress in Deciphering the Biosynthesis of Aspartate-Derived Amino Acids in Plants显示文摘植物直接或间接地是大多数在动物食谱的必要氨基酸的来源。都经由一条很好学习的生合成小径从 aspartate 生产的四这些必要氨基的 acidsmethionine, threonine,异白氨酸,和 lysineare。在必要氨基酸给营养的兴趣,导出 aspartate 的氨基酸小径是广泛的研究的题目。另外,因为为经济地重要的除草剂的目标,和一些下游的产品是为象乙烯和 S-adenosylmethionine 那样的另外的必要植物代谢物的 biosynthetic 先锋,几小径酶服务。关于氨基酸的导出 aspartate 的家庭的最近、进行中的研究识别了新酶活动,规章的机制,并且在 vivo 新陈代谢的功能。一起,这些发现将为植物开创新可能性新陈代谢的工程。 | Georg Jander Vijay Joshi | 2010 | Molecular Plant2010，3，1： | 12 |
| 13 | On-table reconstruction and fixation of Mason type III radial head fractures显示文摘 | G.N. Kiran Kumar Gaurav Sharma Kamran Farooque Vijay Sharma Vaibhav Jain Ravijot Singh Vivek Morey | 2015 | Chinese Journal of Traumatology2015，18，5： | 12 |
| 14 | Hepatocellular adenoma: An update显示文摘Hepatocellular adenomas(HCA) are rare benign liver tumors.Recent technological advancements have helped in the early identification of such lesions.However,precise diagnosis of hepatocellular incidentalomas remains challenging.Studies at the molecular level have provided new insights into the genetics and pathophysiology of these lesions.These in turn have raised questions over their existing management modalities.However,the rarity of the tumor still restricts the quality of evidence available for current recommendations and guidelines.This article provides a comprehensive review on the etiology,molecular biology,pathophysiology,clinical manifestations,and complications associated with HCA.It also elaborates on the genetic advancements,existing diagnostic tools and current guidelines for management for such lesions. | Adarsh Vijay Ahmed Elaffandi Hatem Khalaf | 2015 | World Journal of Hepatology2015，7，25： | 12 |
| 15 | Outcome of distal end clavicle fractures treated with locking plates显示文摘 | Raju Vaishya Vipul Vijay Vikram Khanna | 2017 | Chinese Journal of Traumatology2017，20，1： | 12 |
| 16 | Magnesium matrix composites for biomedical applications:A review显示文摘In recent years,a new wave of bioactive,biocompatibility and biodegradable metallic materials were developed for orthopedic applications.Pure Magnesium,Magnesium alloys,Magnesium alloy-based composites are extensive material to the biomedical applications,by virtue of its high biocompatibility and reasonable strength.Pure magnesium,Magnesium alloys can corrode too fast during the physiological conditions and loses their properties before bone heal.The new era for the development of magnesium-based composites can satisfy the orthopedic applications.Magnesium-based composites,as bio-materials,can produce adjustable mechanical properties like Ultimate tensile strength,ductility,elastic modulus,and corrosion resistance in the physiological conditions.In the Mg based composites,the matrix materials are biomedical magnesium alloys base like Mg-Ca,Mg-Al,Mg-Zn,and Mg-REE alloy and The reinforcements are based on hydroxyapatite(HAP),calcium polyphosphate(CPP),andβ-tricalcium phosphate(β-TCP)particles.This comprehensive review is focused on different grades of biodegradable magnesium matrix composites including their mechanical properties and corrosion resistance. | Vijay Kumar Bommala Mallarapu Gopi Krishna ChTirumala Rao | 2019 | Journal of Magnesium and Alloys2019，7，1： | 12 |
| 17 | Role of bacteria in carcinogenesis, with special reference to carcinoma of the gallbladder显示文摘Carcinoma of the gallbladder (CaGB) is the fifth commonest gastrointestinal tract cancer and is endemic in several countries. The interplay of genetic susceptibility, infections, and life style factors has been proposed to be responsible for carcinogenesis of gallbladder. Persistence of infection leading to chronic inflammation, and production of certain toxins and metabolites with carcinogenic potentials, by certain bacteria has been speculated to be involved in the transformation of the gallbladder epithelium. Therefore, any bacteria that have evolved to acquire both of the above carcinogenic mechanisms can cause cancer. Salmonella typhi has been found to be prominently associated with CaGB. Chronic typhoid carriage (persistence) and production of mediators of chronic infl ammation and a genotoxic toxin (cytotoxic distending toxin, CdtB) are also known for this bacterium. Furthermore, the natural concentrating function of the gallbladder might amplify the carcinogenic effect of the mediators of carcinogenesis. In addition to S. typhi, certain species of Helicobacter (H. bilis and H. hepaticus) and Escherichia coli have also been implicated in carcinogenesis. As the isolation rate is verypoor with the presently available culture techniques, the existence of bacteria in a viable but non-cultivable state is quite likely; therefore, sensitive and specif ic molecular techniques might reveal the etiological role of bacterial infection in gallbladder carcinogenesis. If bacteria are found to be causing cancers, then eradication of such infections might help in reducing the incidence of some cancers. | Gopal Nath Anil K Gulati Vijay K Shukla | 2010 | World Journal of Gastroenterology2010，16，43： | 12 |
| 18 | A Review on Pharmacological and Analytical Aspects of Diosmetin:A Concise Report显示文摘Plants have been used as a source for food material and natural remedies for the treatment of vast range of diseases.Nature provides us remedies for the treatment of various types of disorders ranging from simple ailments to complicated diseases.Plants are known to possess different pharmacological activities due to the presence of various phytoconstituents.Flavonoids are one of the main active phytoconstituents found in fruits,vegetables,wines,tea and cocoa.Flavonoids exhibit various pharmacological activities such as antioxidant,anti-inflammatory,anti-allergic,antibacterial,oestrogenic,cytotoxic antitumoural,hepatoprotective,antithrombotic and antiviral activity.Diosmetin(3',5,7-trihydroxy-4'-methoxyflavone),the aglycone part of the flavonoid glycosides diosmin occurs naturally in citrus fruit.Although it is found in herbal medicines and plays an important role in the treatment of various ailments,only limited scientific researches have been conducted.The aim of this review is to collect all available scientific literature published on diosmetin and combine it into this paper.This review contains an overview of pharmacological activities,isolation techniques and analytical techniques for diosmetin.Thus,valuable information provided in the present review will help researchers in developing alternative methods for the treatment of diseases from diosmetin. | Kanika Patel Manoj Gadewar Vijay Tahilyani Dinesh Kumar Patel | 2013 | Chinese Journal of Integrative Medicine2013，19，10： | 11 |
| 19 | Processing and design methodologies for advanced and novel thermal barrier coatings for engineering applications显示文摘 | Vijay Kumar Balasubramanian Kandasubramanian | 2016 | Particuology2016，14，4： | 11 |
| 20 | Acute femoral artery pseudoaneurysm due to lesser trochanter fragment: an unusual complication of an intertrochanteric fracture显示文摘大腿骨的动脉的假动脉瘤是 intertrochanteric 骨折的稀罕复杂并发症。大多数这些状况由于因医生之治疗而引的损伤或损伤本身并且被打乱的骨头碎片很少引起。这里,我们报导从更小的 trochanter 碎片的尖铁与表面的大腿骨的动脉的 pseudoaneurysm 尖锐地介绍了的一个 72 岁的人的一个案例。有盖住的 stent 的 pseudoaneurysm 的经皮的 endovascular 处理在一个迫切基础上被承担。五天以后,病人被操作在之上,更小的 trochanter 碎片通过一个前面的切口被切除, intertrochanteric 骨折用动态新潮的螺丝钉被修理。破裂在 10 个星期被统一。在 one-year’s 后续,没有接枝相关的复杂并发症。这个案例说明那有代替的更小的 trochanter 碎片的 intertrochanteric 破裂能与流血和大腿骨的动脉的 pseudoaneurysm 尖锐地介绍。 | Gaurav Sharma Ravijot Singh Atin Kumar Vijay Sharma Kamran Farooque | 2013 | Chinese Journal of Traumatology2013，16，5： | 11 |
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