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| 1 | Current concepts on osteonecrosis of the femoral head显示文摘It is estimated that 20000 to 30000 new patients are diagnosed with osteonecrosis annually accounting for approximately 10% of the 250000 total hip arthroplasties done annually in the United States. Thelack of level 1 evidence in the literature makes it difficult to identify optimal treatment protocols to manage patients with pre-collapse avascular necrosis of the femoral head, and early intervention prior to collapse is critical to successful outcomes in joint preserving procedures. There have been a variety of traumatic and atraumatic factors that have been identified as risk factors for osteonecrosis, but the etiology and pathogenesis still remains unclear. Current osteonecrosis diagnosis is dependent upon plain anteroposterior and frog-leg lateral radiographs of the hip, followed by magnetic resonance imaging(MRI). Generally, the first radiographic changes seen by radiograph will be cystic and sclerotic changes in the femoral head. Although the diagnosis may be made by radiograph, plain radiographs are generally insufficient for early diagnosis, therefore MRI is considered the most accurate benchmark. Treatment options include pharmacologic agents such as bisphosphonates and statins, biophysical treatments, as well as joint-preserving and joint-replacing surgeries. the surgical treatment of osteonecrosis of the femoral head can be divided into two major branches: femoral head sparing procedures(FHSP) and femoral head replacement procedures(FHRP). In general, FHSP are indicated at pre-collapse stages with minimal symptoms whereas FHRP are preferred at post-collapse symptomatic stages. It is difficult to know whether any treatment modality changes the natural history of core decompression since the true natural history of core decompression has not been delineated. | Joaquin Moya-Angeler Arianna L Gianakos Jordan C Villa Amelia Ni Joseph M Lane | 2015 | World Journal of Orthopedics2015，6，8： | 94 |
| 2 | Epidermal growth factor reduces ischemia-reperfusion injury in rat small intestine显示文摘 | Villa X Wkuluz J LSchleien C | 2002 | Crit Care Med2002，30，： | 1 |
| 3 | Polychlorinated naphthalenes in air and snow in the Norwegian Arctic: a local source or an Eastern Arctic phenomenon? 显示文摘 | Herbert B M J Halsall C J Villa S | 2005 | Science of the Environment2005，342，： | 1 |
| 4 | Monitoring the effects of drug treatment in rat models of disease by serum protein analysis显示文摘 | Gianazza E Eberini I Villa P Fratelli M Pinna C Wait R | 2002 | J Chromatogr B Analyt Technol Biomed Life Sci2002，771，12： | 1 |
| 5 | Human neural stem cell in vitro, A focus on their isolation and perpetuation 显示文摘 | Villa F Javier Rubio B Navarro C | 2001 | Bio Med Pharmacother2001，55，： | 1 |
| 6 | A comparative ultrastructural study of chondrosarcoma chordoid sarcoma and chordoma显示文摘 | Pardo-Mindan FJ Guillen FJ Villas C | 1981 | Cancer1981，47，11： | 1 |
| 7 | Cyclic stress-strain behavior of reinforcing steel including effect of buckling 显示文摘 | Rodriguez M E Botero J C Villa J | 1999 | Journal of Structural Engineering1999，125，6： | 1 |
| 8 | The genetic and biochemical basis of Omenn syndrome显示文摘 | Santagata S Villa A Sobacchi C | 2000 | Immunol Rev2000，178，： | 1 |
| 9 | The use of VR in the treatment of panic disorders and agoraphobia显示文摘 | Botella C Villa H García Palacios A | | 0，，： | 1 |
| 10 | Determination of solublecarbohydrates in yogurts by high performance liquid chromatography显示文摘 | VALVERDE V C VILLA C M HERRANZ J | 1983 | Journal of Dairy Science1983，67，4： | 1 |
| 11 | Human osteoblast-like cell proliferation induced by calcitonin-related peptides involves PKC activity显示文摘 | Villa I Dal Fiume C Maestroni A | 2003 | Am J Physiol Endocrinol Metab2003，284，3： | 1 |
| 12 | Bisphosphonate treatment in osteoporosis: optimal duration of therapy and the incorporation of a drug holiday 显示文摘 | VILLA J C GIANAKOS A LANE J M | 2016 | HSSJ2016，12，1： | 1 |
| 13 | Hydrotalcites and organic-hydrotalcites as sorbents for removing pesticides from water显示文摘 | Villa M V Sanchez M M J Sanchez C M | 1999 | Journal of Environmental Science and Health Part B-Pesticides Food Contaminants and Agriculture Wastes1999，34，3： | 1 |
| 14 | Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells显示文摘 | Folini M Brambilla C Villa R | 2005 | Eur J Cancer2005，416，： | 1 |
| 15 | Prenatal diagnosis of RAG-deficient Omenn syndrome显示文摘 | Villa A Bozzi F Sobacchi C | 2000 | Prenat Diagn2000，20，1： | 1 |
| 16 | Celecoxib and heterotopic bone formation after total hip arthroplasty 显示文摘 | Lavernia C J Contreras J S Villa J M | 2014 | J Arthroplasty2014，29，2： | 1 |
| 17 | Organoehlorine compounds in ice melt water from Italian Alpine rivers 显示文摘 | Villa S Negrelli C Finizio A | 2006 | Ecotoxicology and Environmental Safety2006，63，： | 1 |
| 18 | Metacarpophalangeal subluxation:locked finger显示文摘 | Vernet AB Lopez-Sicilia S Villas C | | 0，，06： | 1 |
| 19 | Ziprasidone as coadjuvant treatment in resistant obsessive-compulsive disorder treatment 显示文摘 | IQLESIAS G C SANTAMARINA M S ALONSO VILLA M J | 2006 | Actas Exp Psiquiatr2006，34，4： | 1 |
| 20 | Comparison of glacial and non-glaeial-fed streams to evaluate the loading of persistent organic pollutants through seasonal snow/ice melts 显示文摘 | Bizzotto E C Villa S Vaj C etal | 2009 | Chemosphere2009，74，7： | 1 |
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