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| 1 | Obstructive jaundice due to hepatobiliary cystadenoma or cystadenocarcinoma显示文摘Hepatobiliary cystadenomas (HBC) and cystadenocarci- nomas are rare cystic lesions. Most patients with these lesions are asymptomatic, but presentation with ob- structive jaundice may occur. The first patient presented with intermittent colicky pain and recurrent obstructive jaundice. Imaging studies revealed a polypoid lesion in the left hepatic duct. The second patient had recurrent jaundice and cholangitis. Endoscopic retrograde cholan- giopancreatography (ERCP) showed a cystic lesion at the confluence of the hepatic duct. In the third patient with intermittent jaundice and cholangitis, cholangioscopy re- vealed a papillomatous structure protruding into the left bile duct system. In the fourth patient with obstructive jaundice, CT-scan showed slight dilatation of the intrahe- patic bile ducts and dilatation of the common bile duct of 3 cm. ERCP showed filling of a cystic lesion. All patients underwent partial liver resection, revealing HBC in the specimen. In the fifth patient presenting with obstructive jaundice, ultrasound examination showed a hyperecho- genic cystic lesion centrally in the liver. The resection specimen revealed a hepatobiliary cystadenocarcinoma. HBC and cystadenocarcinoma may give rise to obstruc- tive jaundice. Evaluation with cross-sectional imaging techniques is useful. ERCP is a useful tool to differentiate extraductal from intraductal obstruction. | Deha Erdogan Olivier RC Busch Erik AJ Rauws Otto M van Delden Dirk J Gouma Thomas M van Gulik | 2006 | World Journal of Gastroenterology2006,12,35: | 26 |
| 2 | Results of percutaneous sclerotherapy and surgical treatment in patients with symptomatic simple liver cysts and polycystic liver disease显示文摘AIM: To evaluate the results of the treatment of simple liver cysts (solitary and multiple) and polycystic liver disease (PLD) using percutaneous sclerotherapy and/or surgical procedures in a single tertiary referral centre. METHODS: Retrospective analysis of 54 patients referred for evaluation and possible treatment of simple liver cysts (solitary and multiple) and PLD, from January 1997 to July 2006. RESULTS: Simple liver cysts were treated in 41 pts (76/) with a mean size of 12.6 cm. The most common reason for referral was abdominal pain or discomfort (85/). Percutaneous sclerotherapy was performed as initial treatment in 30 pts, showing cyst recurrence in 6 pts (20/). Surgical treatment was initially performed in 11 pts with cyst recurrence in 3 pts (27/). PLD was treated in 13 pts (24/) with a mean size of the dominant cyst of 13 cm. Percutaneous sclerotherapy for PLD was performed in 9 pts with recurrence in 7 pts (77.8/). Surgical treatment for PLD was undertaken in 4 pts (30.8/) with recurrence in all. Eventually, 2 pts with PLD in the presence of polycystic kidney disease underwent liver-and kidney transplantation because of deterioration of liver and kidney function. CONCLUSION: The majority of patients with simple liver cysts and PLD are referred for progressive abdominal pain. As initial treatment, percutaneous sclerotherapy is appropriate. Surgical deroofing is indicated in caseof cyst recurrence after percutaneous sclerotherapy. However, the results of percutaneous sclerotherapy and surgical treatment for PLD are disappointing. Partial liver resection is indicated when there is suspicion of a pre-malignant lesion. | Deha Erdogan Otto M van Delden Erik AJ Rauws Olivier RC Busch Johan S Lameris Dirk J Gouma Thomas M van Gulik | 2007 | World Journal of Gastroenterology2007,13,22: | 15 |
| 3 | 健康女性隔日给予阿司匹林预防癌症、心血管疾病和胃肠道出血风险的个体化预测显示文摘阿司匹林在癌症和心血管疾病(cardiovascular disease,CVD)一级预防中的作用仍不清楚。该研究旨在确定女性使用阿司匹林治疗是否能改善发生癌症、CVD和重大消化道出血的风险。方法:对女性健康研究(一项随机试验,隔日服用阿司匹林100mg/安慰剂的临床实验)中拥有血浆样本的健康女性27 939人进行长期随访,个体化预测使用阿司匹林是否降低合并CVD、癌症和主要消化道出血的绝对风险。 | 刘莉 叶鹏 van Kruijsdijk RC Visseren FL Ridker PM Dorresteijn JA Buring JE van der Graaf Y Cook NR | 2014 | 中华高血压杂志2014,22,12: | 2 |
| 4 | Correlation between Saccharomyces cerevisiae DNA in intestinal mucosal samples and anti-Saccharomyces cerevisiae antibodies in serum of patients with IBD显示文摘瞄准:调查在粘膜 S 的 ASCA 和存在之间的关联。在 CD, ulcerative (UC ) 病人和控制的一张人口的啤酒 DNA。方法:S。cerevisiae 特定的教材和一根荧光灯的探针为 5' exonuclease 实时 PCR (TaqMan ) 试金被设计,它是用为在实时的 PCR 产品的察觉的一根荧光灯标签的探针的一个同质的系统。我们在一组 76 煽动性的肠疾病(IBD ) 与 ASCA 调查结果分析了 PCR 结果的关系病人(31 CD, 45 UC ) 并且 22 健康控制(HC ) 。结果:ASCA (IgA 或 IgG ) 在 19 是积极的(61%) 有 CD 的病人, 12 (27%) 与 HC 的 UC 和没有。PCR 扩大在 10 从最后的结果被禁止并且排除(22%) UC 病人, 7 (22%) CD 病人,并且 6 (30%) HC。在里面仅仅, 15 粘膜取样, S。啤酒 DNA 被实时 PCR 检测,包括 7 (29%) 在 CD, 7 (19%) 在 UC, 1 (6%) 在 HC。在 4 CD 并且在 4 个 UC 病人, ASCA 和粘膜 S。啤酒是积极的。粘膜 S。啤酒在 3 UC,和 3 个 CD 病人在有否定 ASCA IgA 和 IgG 的联合是在场的。结论:自从 S 的存在,我们结束那。在结肠的粘膜活体检视标本的啤酒是很稀罕的, ASCA 是不大可能的被连续暴露向 S 解释。在粘膜的啤酒。因此, ASCA 形成必须在生命更早发生,层次在免疫学的此后仍然保持相对稳定易受影响的人。 | RC Mallant-Hent M Mooij BME von Blomberg RK Linskens AA van Bodegraven PHM Savelkoul | 2006 | World Journal of Gastroenterology2006,12,2: | 2 |
| 5 | Neuroendocrinology of prolonged critical illness: effect of continuous thyrotropin-releasing hormone infusion and its combination with growth hormone-secretagogues显示文摘 | Zegher F Baxter RC | 1998 | J Clin Endocrinol Metab1998,83,: | 1 |
| 6 | Effects of augmented exercise therapy time after stroke: a meta-analysis 显示文摘 | Kwakkel G van Peppen R Wagenaar RC | 2004 | Stroke2004,35,: | 1 |
| 7 | Impact of tumor size and tracer uptake heterogeneity in (18)F-FDG PET and CT non- small cell lung cancer tumor delineation显示文摘 | Hatt M Cheze-le RC van BA | 2011 | J Nucl Med2011,52,11: | 1 |
| 8 | Maternal care and hippocampal plasticity: evidencefor experience-dependent structural plasticity, altered synaptic functioning, and differential responsiveness to glucocorticoids and stress 显示文摘 | Champagne DL Bagot RC Van HF | 2008 | J Neurosci2008,28,23: | 1 |
| 9 | The early history of tubulation in nerve repair显示文摘 | IJpma FF Van De Graaf RC Meek MF | | 0,,05: | 1 |
| 10 | In vitro formation of DNA adducts by cisplatin,lobaplatin and oxaliplatin in calf thymus DNA in solution and in cultured human cells显示文摘 | Van De Vaart P Rietbroek RC | 1996 | Carcinogenesis1996,17,12: | 1 |
| 11 | Transpedicular wedge resection osteotomy for the treatment of a kyphotic Andersson lesion complicating ankylosing spondylitis 显示文摘 | Van Royen BJ Kastelijns RC Noske DP etal | 2006 | Eur Spine J2006,15,2: | 1 |
| 12 | Cross-reactivity of IgE antibodies to allergens显示文摘 | Aalberse RC Akkerdaas J Van Ree R | 2001 | Allergy2001,56,6: | 1 |
| 13 | Alternative handflaps for amputations and digital defects 显示文摘 | Russell RC Van Beek AL Wavak P | 1981 | J Hand SurgAm1981,6,4: | 1 |
| 14 | Muscle activity during gait initiation in normal elderly people显示文摘 | Mickelborough J van der Linden ML Tallis RC | 2004 | Gait Posture2004,19,1: | 1 |
| 15 | Allogeneic bone marrow transplantation for poor-prognosis lymphoma: response,toxicity and survival depend on disease histology显示文摘 | van Besien KW Mehra RC Giralt SA | 1996 | Am J Med1996,100,: | 1 |
| 16 | The role of coping strategies in quality of life of adolescents with asthma显示文摘 | Van De Ven MO Engels RC Sawyer SM Otten R Van Den Eijnden RJ | 2007 | Qual Life Res2007,,2: | 1 |
| 17 | Functionally linked resting-state networks reflect the underlying structural connectivity architecture of the human brain 显示文摘 | van den Heuvel MP Mandl RC Kahn RS | 2009 | Hum Brain Mapp2009,30,: | 1 |
| 18 | Novel pathways in the pathogenesis of respiratory, syncytial virus disease 显示文摘 | Van SM Welliver RC Kimpen JL | 2000 | Pediatr Pulmonol2000,30,2: | 1 |
| 19 | Current good manufacturing practice in plant automation of biological production processes显示文摘 | Dorresteijn RC Wieten G van Santen PTE | 1997 | Cytotech1997,23,: | 1 |
| 20 | Bioequivalence of subcutaneous injections of recombinant human follicle stimulating hormone(Puregon(R))by Peninjector and syringe显示文摘 | Voortman G van de Post J Schoemaker RC | 1999 | Hum Reprod1999,14,: | 1 |