维普中文期刊产品整合服务
106篇 您的检索式:作者名="WERT J"
    题名 作者 年代 出处 被引量
1Lipid peroxidation associated with accelerated aging of soybean axes 显示文摘ST E WERT R C BEWLEY J D 1980Plant Physiology1980,65,3:1
2Dislocation boundary formation in a cold-rolled cube-oriented A1 single crystal 显示文摘Wert J A Liu Q Hansen N 1997Acta Materialia1997,45,6:1
3Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis,causing respiratory failure in newborn mice显示文摘Clark JC Wert SE Bachurski C J 0,,:1
4The role of stacking fault energy and induced residual stresses in the sliding wear of aluminum bronze 显示文摘WERT J J SINGGERMAN S A CALDWELL S G etal 1983Wear1983,91,3:1
5A local model for the thermomechanical conditions in friction stir welding显示文摘Schmidt H Hattel J Wert J 0,,01:1
6Grain refinement in 7075 aluminum by thermomechanical processing 显示文摘Wert J A Paton N Hamilton C 1981Metall Trans A1981,12,7:1
7Neuroretinal hypoxic signaling in a new preclinical murine model for proliferative diabetic retinopathy显示文摘Diabetic retinopathy(DR)affects approximately one-third of diabetic patients and,if left untreated,progresses to proliferative DR(PDR)with associated vitreous hemorrhage,retinal detachment,iris neovascularization,glaucoma and irreversible blindness.In vitreous samples of human patients with PDR,we found elevated levels of hypoxia inducible factor 1 alpha(HIF1α).HIFs are transcription factors that promote hypoxia adaptation and have important functional roles in a wide range of ischemic and inflammatory diseases.To recreate the human PDR phenotype for a preclinical animal model,we generated a mouse with neuroretinal-specific loss of the von Hippel Lindau tumor suppressor protein,a protein that targets HIF1αfor ubiquitination.We found that the neuroretinal cells in these mice overexpressed HIF1αand developed severe,irreversible ischemic retinopathy that has features of human PDR.Rapid progression of retinopathy in these mutant mice should facilitate the evaluation of therapeutic agents for ischemic and inflammatory blinding disorders.In addition,this model system can be used to manipulate the modulation of the hypoxia signaling pathways,for the treatment of non-ocular ischemic and inflammatory disorders.Katherine J Wert Vinit B Mahajan Lijuan Zhang Yuanqing Yan Yao Li Joaquin Tosi Chun Wei Hsu Takayuki Nagasaki Kerstin M Janisch Maria B Grant MaryAnn Mahajan Alexander G Bassuk Stephen H Tsang 2016Signal Transduction and Targeted Therapy2016,1,1:1
8Identification of Precipitates in 7075 Al after high-temperature aging显示文摘WERT J A 1981Scripta Metallurgica1981,15,:1
9Grain refinement in 7075 aluminum by thermomechani- cal processing 显示文摘Wert J A Paton N E Hamilton C H 1981Met Trans A1981,12,:1
10Use of Pu-Be source to simulate neutron-induced single event upsets in static RAMS显示文摘NORMAND E WERT J L DOHERTY W R 1988Nuclear Science1988,35,6:1
11Interleukin-1 beta causes pulmonary inflammation,emphysema,and airway remodeling in the adult murine lung显示文摘Lappalainen U Whitsett J A Wert S E 2005Am J RespiR Cell Mol Biol2005,32,4:1
12Identification of precipitates in 7075 A1 after high-temperature aging 显示文摘WERT J A 1981Scripta Materialia1981,15,:1
13Angular dependence of single event sensitivity in hardened flip/flop designs显示文摘BAZE M P HUGHLOCK B WERT J 0,,06:1
14An analytical model for the heat generation in friction stir welding显示文摘Schmidt H Hattel J Wert J 2004Modelling and Simulation in Materials Science and Engineering2004,12,:1
15A modeling of recrystallization in alloyswith a bimodal particle size distribution 显示文摘NES E WERT J A 1984Scripta Metallurgica1984,18,12:1
16Expression of a human surfactant protein C mutation associated with interstitial lung disease disrupts lung development in transgenic mice显示文摘 WERT S E NOGEE L M 2003J Biol Chem2003,278,52:1
17Leptospiral lipopolysac- charide activates cells through a TLR2-dependent mechanism 显示文摘Werts C Tapping R I Mathison J C 2001Nat Immunol2001,2,4:1
18Dislocation boundaries andactive slip systems显示文摘Wert J Liu Q Hansen N 1995Acta Metall Mater1995,43,:1
19Dislocation boundary formation in a cold-rolled cube-oriented Al single crystal 显示文摘Wert J A Liu Q Hansen N 1997Acta Mater1997,45,6:1
20The effect of partial crystallization on elevated temperature flow stress and room temperature hardness of a bulk amorphous Mg60Cu30Y10 alloy显示文摘WOLF U PRYDS N JOHNSON E WERT J A 2004Acta Materialia2004,52,7:1
返回顶部 每页显示:
共6页 首页 上一页 第1页 下一页 末页 /6 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费