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1201篇 您的检索式:作者名="WILKES M"
    题名 作者 年代 出处 被引量
1Tumor Antigen Specific Activation of Primary Human T-Cells Expressing a Virally Encoded Chimeric T-Cell Receptor Specific for p185HER2显示文摘We have developed and tested chimeric T-cell receptors (TCR) specific for p185HER2. In these experiments, retroviral vectors expressing the N29γ or N29ζ receptors were constructed in pRET6. Amphotropic viral producer cells were established in the GALV-based PG13 packaging cell line. Ficoll purified human peripheral blood lymphocytes (PBL) were virally transduced using an optimized protocol incorporating activation with immobilized anti-CD3/anti-CD28 monoclonal anti- bodies, followed by viral infection in the presence of fibronectin fragment CH296. Transduced cells were co-cultured with human tumor cell lines that overexpress (SK-OV-3) or underexpress (MCF7) p185HER2 to assay for antigen specific im- mune responses. Both CM+ and CD8+ T-cells transduced with the N29γ or N29ζ chTCR demonstrated HER2-specific anti- gen responses, as determined by release of Th1 like cytokines, and cellular cytotoxicity assays. Our results support the fea- sibility of adoptive immunotherapy with genetically modified T-cells expressing a chTCR specific for p185HER2.杨建民 Michael S FRIEDMAN Christopher M REYNOLDS Marianne T HUBEN Lee WILKE Jennifer FULLER 李桥 Zelig ESHHAR James J MULE Kevin T MCDONAGH 2004Journal of Microbiology and Immunology2004,2,4:5
2显示文摘Wilk G D Wallace R M Anthony J M 2001Journal of Applied Physics2001,89,10:2
3Thin film transistor and diode addressed AMLCDs on polymer substrates显示文摘Young N D Bunn B M Wilks R W 1997Journal of the Society for Information Display1997,5,3:2
4IFN-gammainducible protein-10 attenuates bleomycin-induced pulmonary fibrosis via inhibition of angiogenesis显示文摘Keane M P Wilke C A Burdick M D 1999J Immunol1999,163,56:2
5Systemic inflammation and copd: the framing, ham heart study 显示文摘Walter R E Wilk J B Larson M G 2008Chest2008,133,1:1
6显示文摘 Gong H Wilk G D 2002Appl Phys Lett2002,81,:1
7Size-controlled hydroxyapatite nanoparticles as self-organized organicinorganic composite materials显示文摘Rusu V M Ng C H Wilke M 2005Biomaterials2005,26,:1
8Accurate spin-dependent electron liquid correlation energies for local spin density calculations: A critical analysis显示文摘Vosko S H Wilk L Nusair M 1980CanJPhys1980,59,8:1
9The uptake of copper by plants dominantly growing on copper mining spoils along the Yangtze River, the People's Republic of China 显示文摘Tang S R Wilke B M Huang C Y 1999Plant Soil1999,209,:1
10Air and Water Stable 1-Ethyl-3-Methylimidazolium Based Ionic Liquids显示文摘Wilkes J S Zaworotko M J 1992J Chem Soc Chem Commun1992,13,:1
11Absorption of ultra-intense laser pulses显示文摘Wilks S C Kruer W L Tabak M 1992Phys Rev Lett1992,69,9:1
12Prediction of out-come after paraquat poisoning by measurement of the plasma pa-raquat concentration显示文摘Senarathna L Eddleston M Wilks M F 2009QJ Med2009,102,4:1
13Air and water stable 1-ethyl-3 methylimidazolium based ionic liquids 显示文摘WILKES J S ZAWOROTKO M J 1992Journal of the American Chemical Society Chemical Communications1992,13,:1
14显示文摘 2003J Catal2003,219,:1
15Air and water stable 1 ethyl-3- meth-ylim idazolium based ionic liquids 显示文摘WILKES J S ZAWOROTKO M J 1992Chem Commun1992,,13:1
16Increasing Evapotransp iration from the Conterminous United States显示文摘Walter M Todd Daniel S wilks 2004Journal of Hydrology2004,,5:1
17Selenium glutathione peroxidase(GSH-Px) and lipid peroxidation products before and after selenium supplementation显示文摘Wilke B C Vidailhet M Favier A 1992Clin Chim Axta1992,207,2:1
18Prospects for treat- ment of paraquat - induced lung fibrosis with immunosuppresive drugs and the need for better prediction of outcome: A systematic review显示文摘Eddleston M Wilks MF Buekley NA 2003Quar J Med2003,96,11:1
19Sentinel lymph node surgery after neoadjuvant chemotherapy in patients with node-positive breast cancer: the ACOSOG Z1071 (Alliance) clinical trial显示文摘Boughey J C Suman V J Mittendorf E A Ahrendt G M Wilke L G Taback B 2013JAMA2013,310,:1
20Aeeurate Spin-De- pendent Electron Liquid Correlation Energies for Local Spin Density Calculations: A Critical Analysis显示文摘VOSKO S H WILK L NUSAIR M 1980Cana- dian Journal of Physics1980,58,8:1
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