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327篇 您的检索式：作者名="WINTER O"

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	题名	作者	年代	出处	被引量
1	Cyclooxygenase-2 plays a central role in the genesis of pancreatitis and associated lung injury显示文摘BACKGROUND: The exact mechanism by which cyclooxy- genase-2 (COX-2) promotes inflammation in pancreatitis in obscure. This study was undertaken to investigate the role of COX-2 inhibition in an animal model of pancreati- tis , a disease process characterized by a systemic inflamma- tory response and ensuing neutrophil-mediated lung injury. METHODS: Pancreatitis was induced in 24 Sprague-Daw- ley rats by intraperitoneal injection of 20% L-arginine (500 mg/100 g body weight). The animals were randomized into 3 groups (8 rats in each group); controls and rats with pancreatitis intravenously resuscitated with either normal saline (0.9% NaCl 3 ml/kg) at 24 and 48 hours or COX-2 inhibitor (parecoxib 1 mg/kg). Pancreatic and lung inju- ries were assessed histologically. Lung injury was assessed utilizing wet;dry ratio and myeloperoxidase activity to in- dicate pulmonary neutrophil infiltration. A Western blot was used to determine COX-2 protein expression in pancrea- tic tissue. RESULTS: The animals treated with COX-2 inhibitors dis- played significantly less pancreatic and lung injuries than their normal saline counterparts. Histological pancreatic and lung injury scores were significantly reduced (P <0.05) in the COX-2 treated group. Lung wet: dry ratios were sig- nificantly improved and pulmonary neutrophil infiltration was attenuated in the COX-2 group (P<0.05). Western blot analysis confirmed attenuated COX-2 protein expression. CONCLUSION: This study shows, for the first time in a rat model, that adjuvant COX-2 inhibition significandy attenu- ates the severity of both pancreatitis and its associated sys- temic inflammatory response and end-organ injury.	Gavin O'Brien Conor J Shields Desmond C Winter John P Dillon	2005	Hepatobiliary & Pancreatic Diseases International2005，4，1：	12
2	Will advanced lithiumalloy anodes have a chance in lithium-ion batteries 显示文摘	BESENHARD J O YANG J WINTER M	1997	J Power Sources1997，68，：	2
3	A rat model of bone cancer pain显示文摘	S.J Medhurst K Walker M Bowes B.L Kidd M Glatt M Muller M Hattenberger J Vaxelaire T O’Reilly G Wotherspoon J Winter J Green L Urban	2002	Pain2002，，：	2
4	Advances in battery technology:recharge able magnesium batteries and novelnegative-electrode mater ials for lithium ion batteries 显示文摘	BESENHARD J O WINTER M	2002	Chemphyschem2002，3，：	2
5	Prognostic significance of detection of microscopic peritoneal disease in colorectal cancer: A systematic review显示文摘	Helen M. Mohan Donal B. O’Connor James M. O’Riordan Des C. Winter	2013	Surgical Oncology2013，，：	2
6	Contrast enhanced MR angiography in the assessment of relevant steneses in occlusive disease of the pelvic and lower limb arteries:diagnostic value of a two-step examination protocol in comparison to conventional DSA显示文摘	Winterer JT Schaefer O Uhrmeister P	2002	Eur J Radiology2002，41，：	1
7	Management of neuromuscular spinaldeformities with Luque segmental instrumentation显示文摘	Boachie-Adjei O Lonstein JE Winter RB	1989	J Bone JointSurg(Am)1989，71，4：	1
8	The role of laparoscopy in the management of acute small-bowel obstruction:a review of over 2,000 cases显示文摘	O'Connor DB Winter DC		0，，05：	1
9	Cyclic and acyclic sulfites: new solvents and electrolyte additives for lithium ion batteries with graphitic anodic显示文摘	WRODNIGG G H BESENHARD J O WINTER M	2001	Journal of Power Sources2001，9798，：	1
10	Electrochemical lithiation of tin and tin-based intermetallics and composites显示文摘	Winter M Besenhard J O	1999	Electrochim Acta1999，45，12：	1
11	Electrochemical lithiation of tin and tin - based intermetallics and composites 显示文摘	Winter M Besenhard J O	1999	Electrochim Acta1999，45，：	1
12	Biological behaviour and clinical implications of micrometastases显示文摘	Kell MR Winter DC O'Sullivan GC	2000	BrJ Surg2000，87，12：	1
13	Insertion electrode materials for rechargeable lithium batteries 显示文摘	Winter M Besenhard J O Sphar MS	1998	Advanced Materials1998，10，：	1
14	Electrochemical Iithiation of tin and tin-based intermetallics and composites显示文摘	Winter M Besenhard J O	1999	Electrochim Acta1999，45，12：	1
15	Tin and tin-based intermetallics as new anode materials for lithium-ion cells显示文摘	Wachtler M Besenherd J O Winter M	2001	J Power Sources2001，94，2：	1
16	Inflammatory Bowel Disease in African American Children Compared With Other Racial/Ethnic Groups in a Multicenter Registry显示文摘	Jolanda M. White Siobhán O’Connor Harland S. Winter Melvin B. Heyman Barbara S. Kirschner George D. Ferry Stanley A. Cohen Robert N. Baldassano Terry Smith Traci Clemons Benjamin D. Gold	2008	Clinical Gastroenterology and Hepatology2008，，12：	1
17	Sentinel lymph nodemapping in colorectal cancer 显示文摘	Mulsow J Winter DC O' Keane JC	2003	Br J Surg2003，90，6：	1
18	Insertion electrode materials for rechargeable lithium batteries显示文摘	Winter M Besenhard J O Sphar M S	1998	Advanced Materials1998，10，10：	1
19	Electrochemical lithiation of fin and tin-based intermetallics and composites显示文摘	WINTER M BESENHARD J O		0，，：	1
20	The role of laparoscopy in the management of acute small-bowel obstruction:a review of over 2,000cases显示文摘	O'Connor DB Winter DC	2012	Surg Endosc2012，26，1：	1

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