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| 1 | High efficiency, high power 808nm laser array and stacked arrays optimized for elevated temperature operation显示文摘Operation of 808-nm laser diode pumping at elevated temperature is crucial to many applications. Reliable operation at high power is limited by high thermal load and low catastrophic optical mirror damage (COMD) threshold at elevated temperature range. We demonstrated high efficiency and high power operation at elevated temperature with high COMD power. These results were achieved through device design optimization such as growth conditions, doping profile, and materials composition of the quantum-well and other layers. Electrical-to-optical efficiency as high as 62% was obtained through lowered threshold current, lowered series resistance and increased slope efficiency. The performance of single broad-area laser diodes scales to that of high power single bars on water-cooled copper micro-channel heatsinks or conductively-cooled CS heatsinks. No reduction in bar performance or significant spectral broadening is seen when these micro-channel coolers are assembled into 6-bar and 18-bar CW stacks for the highest power levels. | Crump P A Crum T R DeVito M Farmer J Grimshaw M Huang Z Igl S A Macomber S Thiagarajan P Wise D | 2004 | 光机电信息2004，21，6： | 4 |
| 2 | Identification of pathologic features associated with “ulcerative colitis-like” Crohn's disease显示文摘AIM: To identify pathologic features associated with this 'ulcerative colitis(UC)-like' subgroup of Crohn's disease(CD).METHODS: Seventeen subjects diagnosed as having UC who underwent proctocolectomy(RPC) from 2003-2007 and subsequently developed CD of the ileal pouch were identified. UC was diagnosed based on preoperative clinical, endoscopic, and pathologic studies. Eighteen patients who underwent RPC for UC within the same time period without subsequently developing CD were randomly selected and used as controls. Pathology reports and histological slides were reviewed for a wide range of gross and microscopic pathological features, as well as extent of disease. The demographics, gross description and histopathology of the resection specimens were reviewed and compared between the two groups. RESULTS: Patients with 'UC-like' CD were on average 13 years younger than those with 'true' UC(P < 0.01). More severe disease in the proximal involved region and active ileitis with/without architectural distortion were observed in 6 of 17(35%) and 7 of 17(41%) 'UC-like' CD cases, respectively, but in none of the 'true' UC cases(P < 0.05). Active appendicitis occurred in 8 of 16(50%) 'UC-like' CD cases but in only two(11%) 'true' UC cases(P < 0.05). Conspicuous lamina propria neutrophils were more specific for 'UClike' CD(76% vs 22%, P < 0.05). In addition, prominent lymphoid aggregates tended to be more common in 'UC-like' CD(P = 0.07). The 'true' UC group contained a greater number of cases with severe activity(78% vs 47%). Therefore, the features more commonly seen in 'UC-like' CD were not due to a more severe disease process. Crohn's granulomas and transmural inflammation in non-ulcerated areas were absent in both groups.CONCLUSION: More severe disease in the proximal involved region, terminal ileum involvement, active appendicitis, and prominent lamina propria neutrophils may be morphological factors associated with 'UC-like' CD. | Samuel D James Paul E Wise Tania Zuluaga-Toro David A Schwartz M Kay Washington Chanjuan Shi | 2014 | World Journal of Gastroenterology2014，20，36： | 4 |
| 3 | The feasibility of surgical site tagging with CT virtual reality of paranasal sinuses显示文摘 | Hopper K D Iyriboz A T Wise S W | 1999 | J Comput Assisi Tomogr1999，23，4： | 1 |
| 4 | Respiratory physiologic changes in pregnancy 显示文摘 | Wise RA Polito A J Krishnan V | 2006 | Immunol Allergy Clin North Am2006，26，： | 1 |
| 5 | Vascular endothe- lial growth factors encoded by Off virus show surprising seque- nce variation but have a conserved functionally relevant structure 显示文摘 | Mercer A A Wise L M Scagliarini A | 2002 | J Gen Virol2002，83，： | 1 |
| 6 | Determination of organic acids in Vaccinium berry standard reference materials显示文摘 | Phillips M M Case R J Rimmer C A Sander L C Sharpless K E Wise S A Yen J H | 2010 | Analytical and Bioanalytical Chemistry2010，398，1： | 1 |
| 7 | Dopamine uptake through the norepinephrine transporter in hrain regions with low levels of the dopamine transporter: evidence from knock-out mouse lines 显示文摘 | Moron JA Brockington A Wise RA | 2002 | J Neurosci2002，22，： | 1 |
| 8 | Challenges of major obstetric hemorrhage 显示文摘 | Wise A Clark V | 2010 | Best pract resclin obstet gynaecol2010，24，3： | 1 |
| 9 | How can drug addiction help us understand obesity? 显示文摘 | VOLKOW N D WISE R A | 2005 | Nat Neurosci2005，8，5： | 1 |
| 10 | Strategies to manage major obstetric haemorrhage显示文摘 | Clark V | 2008 | Curr Opin Anaesthesiol2008，21，3： | 1 |
| 11 | The impedance of stainless-steel electrodes显示文摘 | Geddes L A Da Costa C P Wise G | 1971 | Medical & Biological Engineering1971，9，5： | 1 |
| 12 | Heterodimeriza- tion is required for the formation of a functional GABA (B) receptor 显示文摘 | White J H Wise A Main M J | 1998 | Nature1998，396，： | 1 |
| 13 | Depression and influence on reproductive endocrine and menstrual cycle markers associated with perimenopause:the Harvard Study of Moods and Cycles显示文摘 | HARLOW B L WISE L A OTTO M W | 2003 | Arch Gen Psychiatry2003，60，1： | 1 |
| 14 | The ultrastructure of chilling stress显示文摘 | Kratsch H A Wise R R | 2000 | Plant Cell and Environ2000，23，： | 1 |
| 15 | The ultrastructure of chilling stress 显示文摘 | Kratsch H A Wise R R | 2000 | Plant Cell & Environment2000，23，4： | 1 |
| 16 | Mucosal Detail at CT Virtual Reality: Surfac Eversus Volume Rendering显示文摘 | Hopper K D Iyriboz A T Wise S W | 2000 | Radiology2000，214，2： | 1 |
| 17 | Self-Similar Evolution of Parabolic Pulses in a Laser显示文摘 | ILDAY F (A) O BUCKLEY J R CLARK W G WISE F W | | 0，，： | 1 |
| 18 | The uhrastructure of chilling stress显示文摘 | WISE R R | 2000 | Plant Cell Environ2000，23，： | 1 |
| 19 | An integrated-circuit approach to extracellular microelectrodes 显示文摘 | WISE K D ANGELL J B STARR A | 1970 | IEEE Trans BiomedEng1970，17，3： | 1 |
| 20 | Vital signs: central line-associated blood stream infections-United States, 2001, 2008, and 2009显示文摘 | Srinivasan A Wise M Bell M | 2011 | Morb Mortal Wkly Rep2011，60，8： | 1 |
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