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| 1 | Therapeutic alternatives for the treatment of type 1 hepatorenal syndrome: A Delphi technique-based consensus显示文摘AIM To propose several alternatives treatment of type 1 hepatorenal syndrome(HRS-1) what is the most severe expression of circulatory dysfunction on patients with portal hypertension.METHODS A group of eleven gastroenterologists and nephrologists performed a structured analysis of available literature.Each expert was designated to review and answer a question.They generated draft statements for evaluation by all the experts.Additional input was obtained from medical community.In order to reach consensus,a modified three-round Delphi technique method was used.According to United States Preventive Services Task Force criteria,the quality of the evidence and level of recommendation supporting each statement was graded.RESULTS Nine questions were formulated.The available evidence was evaluated considering its quality,number of patients included in the studies and the consistency of its results.The generated questions were answered by the expert panel with a high level of agreement.Thus,a therapeutic algorithm was generated.The role of terlipressin and norepinephrine was confirmed as the pharmacologic treatment of choice.On the other hand the use of the combination of octreotide,midodrine and albumin without vasoconstrictors was discouraged.The role of several other options was also evaluated and the available evidence was explored and discussed.Liver transplantation is considered the definitive treatment for HRS-1.The present consensus is an important effort that intends to organize the available strategies based on the available evidence in the literature,the quality of the evidence and the benefits,adverse effects and availability of the therapeutic tools described.CONCLUSION Based on the available evidence the expert panel was able to discriminate the most appropriate therapeutic alternatives for the treatment of HRS-1. | Juan P Arab Juan C Claro Juan P Arancibia Jorge Contreras Fernando Gomez Cristian Munoz Leyla Nazal Eric Roessler Rodrigo Wolff Marco Arrese Carlos Benítez | 2016 | World Journal of Hepatology2016，8，25： | 3 |
| 2 | Polymerase chain reaction versus culture for detection of Ureaplasma urealyticum and Mycoplasma hominis in the urogenital tract of adults and the respiratory tract of newborns显示文摘 | Abele-Horn M Wolff C Dressel P | 1996 | Eur J Clin Microbiol Infect Dis1996，15，7： | 1 |
| 3 | Polymerase chain reactionversus culture for detection of Ureaplasma urealyticum and My coplasmahomin is i n the urogenital tract of adults and the respiratory tract of new--borns 显示文摘 | Abele--Hom M Wolff C Dressel P | 1996 | Eur J Clin Microbiol Infect Dis1996，15，： | 1 |
| 4 | Polymerase chain reaction versus culture for detection of Ureaplasma urealyticumand Mycoplasma hominis in the urogenital tract of adults and the respiratory of newborns 显示文摘 | Abele-Hom M Wolff C Dressel P | 1996 | Eur J Clin Microbiol Infect Dis1996，15，7： | 1 |
| 5 | The coefficient of haze as a measure of particulate elemental carbon显示文摘 | Wolff G T Stroup C M Stroup D P | 1983 | Air Pollu Control Associ1983，33，8： | 1 |
| 6 | Polymerase chain reaction versus culture for detection of Ureaplasma urealyticum and Mycoplasma hominis in the urogenital tract of adults and the respiratory tract of newborns显示文摘 | Abele -Hom M Wolff C Dressel P | 1996 | Eur J Clin Microbiol Infect Dis1996，15，： | 1 |
| 7 | Structure and function of the core histone N-termini:more than meets the eye显示文摘 | NSEN J C TSE C WOLFFE A P | 1998 | Biochemistry1998，37，17： | 1 |
| 8 | Association of Ureaplama urealyticum biovars with clinical outcome for neonates , obstetric patients,and gynecological patients with pelvic inflammatory disease显示文摘 | Abele-Horn M Wolff C Dressel P | 1997 | J Clin Microbiol1997，35，5： | 1 |
| 9 | Association of Ureaplasma urealyticum Biovars with Clinical Outcome for Neonates, Obstetric Patients, and Gynecological Patients with Pelvic Inflammatory Disease显示文摘 | Abele-Horn M Wolff C Dressel P | 1997 | J Clin Microbiol1997，35，5： | 1 |
| 10 | Association of Ureaplasma urealyticum biovars with clinical outcome for neonates, obstetric patients and gynecological patients with pelveic inflammatory disease 显示文摘 | Abele-Horn M Wolff C Dressel P | 1997 | J Clin Microbiol1997，35，5： | 1 |
| 11 | Association of Ureaplasma urealyticum biovars with clinical outcome for neonates,obstetric patients,and gynecological patients with pelvic inflammatory disease显示文摘 | Abele-Horn M Wolff C Dressel P | 1997 | J Clin Microbiol1997，35，5： | 1 |
| 12 | Polymerase chain reaction versus culture for detection of Ureaplasma urealyticum and Mycoplasma hominis in the urogenital tract of adults and the respiratory tract of newborns显示文摘 | Abele-Horn M Wolff C Dressel P | 1996 | Eur J Clin Microbiol Infect Dis1996，15，7： | 1 |
| 13 | Assays for laboratory confirmation of novel human coronavirus (hCoV-EMC) infections显示文摘 | Corman V M Mtiller M A Costabel U Timm J Bin- ger T Meyer B Kreher P Lattwein E Eschbach- Bludau M Nitsche A Bleicker T Landt O Schweiger B Drexler J F Osterhaus A D Haagmans B L Dittmer U Bonin F Wolff T Drosten C | 2012 | Euro Surveill2012，17，20： | 1 |
| 14 | Association of Ureaplasma urealyticum biovars with clincal outcome for neonates,obstetric patients,and gynecological patients with pelvic inflammatory disease显示文摘 | Abele-Horn M Wolff C Dressel P | 1997 | J Clin Microbiol1997，35，5： | 1 |
| 15 | Polymerase chain reaction versus culture for detection of Ureaplasma urealyticum and Mycoplasma hominis in the urogenital tract of adults and the respiratory tract of newboms显示文摘 | Abele MH Wolff C Dressel P | 1996 | Eur J Clin Microbiol Infcct Dis1996，15，： | 1 |
| 16 | Hydrogen peroxide production during experimental protein glycation显示文摘 | JIANG Z J WOOLLARDA C S WOLFF S P | 1990 | FEBSLett1990，268，： | 1 |
| 17 | Knowledge and the environment 显示文摘 | Ehrlich P R Wolff G Daily G C | 1999 | Ecological Economics1999，30，2： | 1 |
| 18 | Measuring the forward foreign exchange risk premium: multi-country evidence from unobserved components models 显示文摘 | Wolff C C P | 2000 | Journal of International Financial Markets Institutions and Money2000，10，： | 1 |
| 19 | More evidence on the dollar risk premium in the foreign exchange market 显示文摘 | Bams D Walkowiak K Wolff C C P | 2004 | Journal of International Money and Finance2004，23，： | 1 |
| 20 | Contingent Capital:The Case of Coerces显示文摘 | Pennacchi Theo Vermaelen Christian C P Wolff | 2014 | Journal of Financial and Quantitative Analysis2014，，31： | 1 |
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