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| 1 | Folate Intake, MTHFR Polymorphisms, and Risk of Esophageal, Gastric, and Pancreatic Cancer: A Meta-analysis显示文摘 | Susanna C. Larsson Edward Giovannucci Alicja Wolk | 2006 | Gastroenterology2006，，4： | 3 |
| 2 | 极早早产儿6岁时的神经和发育障碍 | Marlow N. Wolke D. Bracewell M.A. Samara M. 郭俊 | 2005 | 世界核心医学期刊文摘(神经病学分册)2005，0，5： | 3 |
| 3 | Biology of interleukin-22显示文摘 | Kerstin Wolk Ellen Witte Katrin Witte Katarzyna Warszawska Robert Sabat | 2010 | Seminars in Immunopathology2010，，1： | 3 |
| 4 | Alcohol Consumption and Risk of Atrial Fibrillation显示文摘 | Susanna C. Larsson Nikola Drca Alicja Wolk | 2014 | Journal of the American College of Cardiology2014，，3： | 2 |
| 5 | A prospective study of obesity and cancer risk (Sweden)显示文摘 | Alicja Wolk Gloria Gridley Malin Svensson Olof Nyrén Joseph K. McLaughlin Joseph F. Fraumeni Hans-Olov Adami | 2001 | Cancer Causes and Control2001，，1： | 2 |
| 6 | Enhanced caveolin-1 expression in smooth muscle cells: Possible prelude to neointima formation显示文摘AIM: To study the genesis of neointima formation in pulmonary hypertension(PH), we investigated the role of caveolin-1 and related proteins. METHODS: Male Sprague Dawley rats were given monocrotaline(M, 40 mg/kg) or subjected to hypobaric hypoxia(H) to induce PH. Another group was given M and subjected to H to accelerate the disease process(M + H). Right ventricular systolic pressure, right ventricular hypertrophy, lung histology for medial hypertrophy and the presence of neointimal lesions were examined at 2 and 4 wk. The expression of caveolin-1 and its regulatory protein peroxisome proliferator-activated receptor(PPAR) γ, caveolin-2, proliferative and antiapoptotic factors(PY-STAT3, p-Erk, Bcl-x L), endothelial nitric oxide synthase(e NOS) and heat shock protein(HSP) 90 in the lungs were analyzed, and the results from M + H group were compared with the controls, M and H groups. Double immunofluorescence technique was used to identify the localization of caveolin-1 in pulmonary arteries in rat lungs and in human PH lung tissue. RESULTS: In the M + H group, PH was more severe compared with M or H group. In the 4 wk M+H group, several arteries with reduced caveolin-1 expression in endothelial layer coupled with an increased expression in smooth muscle cells(SMC), exhibited neointimal lesions. Neointima was present only in the arteries exhibiting enhanced caveolin-1 expression in SMC. Lung tissue obtained from patients with PH also revealed neointimal lesions only in the arteries exhibiting endothelial caveolin-1 loss accompanied by an increased caveolin-1 expression in SMC. Reduction in e NOS and HSP90 expression was present in the M groups(2 and 4 wk), but not in the M + H groups. In both M groups and in the M + H group at 2 wk, endothelial caveolin-1 loss was accompanied by an increase in PPARγ expression. In the M + H group at 4 wk, increase in caveolin-1 expression was accompanied by a reduction in the PPARγ expression. In the H group, there was neither a loss of endothelial caveolin-1, eNOS or HSP 90, nor an increase in SMC caveolin-1 expression; or any alteration in PPARγ expression. Proliferative pathways were activated in all experimental groups. CONCLUSION: Enhanced caveolin-1 expression in SMC follows extensive endothelial caveolin-1 loss with subsequent neointima formation. Increased caveolin-1 expression in SMC, thus, may be a prelude to neointima formation. | Jing Huang John H Wolk Michael H Gewitz James E Loyd James West Eric D Austin Rajamma Mathew | 2015 | World Journal of Cardiology2015，7，10： | 2 |
| 7 | Folate intake, MTHFR polymorphisms,and risk of esophageal,gastric, and pancreatic cancer:a meta-analysis显示文摘 | Larsson SC Giovannucci E Wolk A | 2006 | Gastroenterology2006，131，4： | 1 |
| 8 | Closing capacity of cranial bone defects using porous calcium phosphate cement imp lants in a rabbit animal model显示文摘 | Kroese-Deutman HC Wolke JG Spauwen PH Jansen JA | 2006 | J Biomed Mater Res A2006，79，3： | 1 |
| 9 | Diabetes and colorectal cancer incidence in the cohort of Swedish men显示文摘 | Larsson SC Giovannucci E Wolk A | 2005 | Diabetes Care2005，28，7： | 1 |
| 10 | Functional, structural, and dynamic basis of electrical heterogeneity in healthy and diseased cardiac muscle: implications for arrhythmogenesis and anti-arrhythmic drug therapy显示文摘 | Wolk R Cobbe SM Hicks MN | 1999 | Pharmacol Ther1999，84，2： | 1 |
| 11 | Regional electrophysiological effects of hypokalaemia, hypomagnesaemia and hyponatraemia in isolated rabbit hearts in normal and ischaemic conditions显示文摘 | WOLK R KANE K A COBBE S M | 1998 | Cardiovasc Res1998，40，： | 1 |
| 12 | IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis 显示文摘 | Wolk K Witte E Wallace E | 2008 | Eur J Immunol2008，36，5： | 1 |
| 13 | Diabetes and risk of endometrial cancer:a population based prospective cohort study显示文摘 | Friberg E Mantzoros CS Wolk A | 2007 | Cancer Epidemiol Biomarkers Prey2007，16，2： | 1 |
| 14 | Long-term dietary cadmium intake andpostmenopausal endometrial cancer incidence:a population-basedprospective cohort study显示文摘 | Akesson A Julin B Wolk A | 2008 | Cancer Res2008，68，15： | 1 |
| 15 | Influence of surgical technique and surface roughness on the primary stability of an im- plant in artificial bone with different cortical thickness: A laboratory study显示文摘 | Tabassum A Meijer GJ Wolke JG | 2010 | Clin Oral Implants Res2010，21，2： | 1 |
| 16 | Air drilling techniques 显示文摘 | Wolke Roy M Deakins Ken Surer Roqer L | 1990 | Geothermal Resources Council Bulletin1990，519，5： | 1 |
| 17 | Diabetic foot infections:a need for innovative assessments显示文摘 | Fisher TK Wolcott R Wolk DM | 2010 | Int J Low Extrem Wounds2010，9，1： | 1 |
| 18 | Histologic investigation of the biologic behavior of different hydroxyapatite plasma-sprayed coatings in rabbits显示文摘 | van der Waerden JP Wolke JG | 1993 | J Biomed Mater Res1993，27，5： | 1 |
| 19 | Studies of solubility of different calcium phosphate ceramic particles in vitro显示文摘 | Klein C P A T Wolke J G C Groot K | 1990 | Biomaterials1990，11，4： | 1 |
| 20 | Trabecular bone response to injectable calcium phosphate (Ca-P)cement显示文摘 | Ooms EM Wolke GC | 2002 | J Biomed Mater Res2002，61，： | 1 |
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