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	题名	作者	年代	出处	被引量
1	国际卒中遗传学联盟的推荐意见(第1部分):标准化表型数据收集显示文摘与几乎所有复杂疾病一样,卒中的患病风险和临床转归也是多基因作用的[1]。探索相关基因突变有望为新型个体化治疗方法奠定基础,从而显著减少卒中对全球健康造成的毁灭性影响。为了达到足够的统计学效能以确认多个风险性等位基因,需要很大的样本量。尽管卒中是全世界范围内第二大致死病因和成年人致残的主要原因[2],但没有任何一家研究机构能独立收集到足够的样本。在认识到这一挑战之后,来自世界各地的卒中研究者们于2007年成立了国际卒中遗传学联盟( International Stroke Genetics Consortium, ISGC; http://www. strokegenetics.org),其使命是通过研究在全球多个研究机构入组的患者来识别影响卒中患病风险、临床预后和治疗效果的遗传学因素。尽管先前已取得了一些成功[3-5],仍有大量工作有待进行,这不仅是为了发现风险性等位基因从而达到卒中个体化医疗的最终目标,更是为了开发综合性卒中风险评估手段以及得到足以改变临床实践的结果[6]。根据糖尿病和冠状动脉疾病等其他复杂疾病的研究进展,为了识别与卒中相关的所有基因突变,需要100000~200000个样本。为了达到这个样本量,需要进行更为广泛的协作。	Jennifer J. Majersik John W.Cole Jonathan Golledge Natalia S. Rost Yu-Feng Yvonne Chan M. Edip Gurol Ame G. Lindgren Daniel Woo Israel Fernandez-Cadenas Donna T. Chen Vincent Thijs Bradford B. Worrall Ayeesha Kamal Paul Bentley Joanna M. Wardlaw Ynte M. Ruigrok Thomas W.K Battey Reinhold Schmidt Joan Montaner Anne-Katrin Giese Jaume Roquer Jordi Jimenez-Conde Chaeyoung Lee Hakan Ay Juan Jose Martin 李海峰岳耀先徐军	2015	国际脑血管病杂志2015，23，9：	3
2	Inflammation, residualkidney function, and cardiac hypertrophy are interrelated and combine adversely to enhance mortality and ardiovasculardeath risk of peritoneal dialysis patients 显示文摘	Wang AY Wang M Woo J	2004	J Am Soc Nephrol2004，15，：	1
3	Is a single time point C-reactive protein predictive of outcome in peritoneal dialysis patients? 显示文摘	Wang AY Woo J Lam CW	2003	J Am Soc Nephrol2003，14，7：	1
4	Inflammation, residual kidney function, and cardiac hypertrophy are interrelated and combine adversely to enhance mortality and cardiovascular death risk of peritoneal dialysis patients显示文摘	Wang AY Wang M Woo J	2004	J Am Soc Nephml2004，15，8：	1
5	Resting energy ex- penditure and subsequent mortality risk in peritoneal di- alysis patients显示文摘	Wang AY Sea MM Woo J	2004	AM Soc Nephrol2004，15，：	1
6	Association of in- flammation and malnutrition with cardiac valve calcifi- cation in continuous ambulatory beritoneal dialysis ha- tients显示文摘	Wang AY Woo J Wang M	2007	J Am Soc Neohorl2007，12，：	1
7	Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes显示文摘	Woo AY Wang TB Zeng X	2009	Mol Pharmacol2009，75，1：	1
8	Cardiac valve calcification as an important predictor for all-cause mortality and cardiovascular mortality in long-term peritoneal dialysis patients a prospective study显示文摘	Wang AY Wang M Woo J	2003	J Am Soc Nephrol2003，14，1：	1
9	Baicalein protects rat cardiomyocytes from hypoxia/reoxygenation damage via a prooxidant mechanism显示文摘	Woo AY Cheng CH Waye MM	2005	Cardiovasec Res2005，65，1：	1
10	Baicalein protects rat cardiomyocytes from hypoxia/reoxygenation damage via a prooxidant mechanism显示文摘	Woo AY Cheng CH Waye MM	2005	Cardiovasc Res2005，65，1：	1
11	Inflammation,residual kidney function,and cardiac hypertrophy are interrelated and combine adversely to enhance mortality and cardiovascular death risk of peritoneal dialysis patients 显示文摘	Wang AY Wang M Woo J	2004	J Am Soc Nephrol2004，15，8：	1
12	Associations of serum fetuin-A with malnutrition,inflammation,atherosclerosis and valvular calcification syndrome and outcome in peritoneal dialysis patients显示文摘	Wang AY Woo J Lam CW	2005	Nephrol Dial Transplant2005，20，8：	1
13	Important differentiation of factors that predict outcome in peritoneal dialysis patients with different degrees of residual renal function 显示文摘	Wang AY Woo J Wang M	2005	Nephrol Dial Transplant2005，20，2：	1
14	Important differentiation of factors that predict outcome in peritoneal dialysis patients with different degrees of residual renal function.显示文摘	Wang AY Woo J Wang M		0，，：	1
15	Inflammation,residual kidney function,and cardiac hypertrophy are interrelated and combine adversely to enhance mortality and cardiovascular death risk of peritoneal dialysis patients显示文摘	Wang AY Wang M Woo J	2004	J Am Soc Nephrol2004，15，：	1
16	Important differentiation of factors that predict outcome in peritoneal dialysis patients with different degrees of residual renal function显示文摘	Wang AY Woo J Wang M	2005	Nephrol Dial Thansplant2005，20，2：	1
17	查看详情显示文摘	Wang AY Wang M Woo J Law MC,		0，，：	1
18	Important differentiation of factors that predict outcome in peritoneal dialysis patients with different degrees of residual renal function显示文摘	Wang AY Woo J Wang M	2005	Nephrol Dial Transplant2005，20，：	1
19	Inflammation, residual kidney function, and cardiac hypertrophy are interrelated and combine adversely to enhance mortality and cardiovascular death risk of peritoneal dialysis patients 显示文摘	Wang AY Wang M Woo J	2004	J Am Soc Nephrol2004，15，8：	1
20	Baicalein protects rat cardiomyocytes from hypoxia/reoxygenation damage via a prooxidant mechanism显示文摘	Cheng CH Waye MM	2005	Cardiovasv Res2005，65，1：	1

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