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| 1 | Cloning of first abc transporter encoding gene from Trichoderma spp. and its expression during stress and mycoparasitism显示文摘Trichoderma in its natural environment competes for nutrient uptake and is required to protect itself from adverse natural toxic compounds, such as those produced by plants and other microbes in the soil community, or synthetic toxic compounds released human activity. One of the most important metabolic pathways for drug resistance and substrate uptake, both in prokaryotes and eukaryotes, is ATP dependent. The role of ABC transporter proteins in the biology of Trichoderma is still not known. We present the cloning of the first four ABC transporter genes (TABC1, TABC2, TABC3, TABC4 ) in Trichoderma, and in particular T. atroviride P1, and the characterization of TABC2 The complete sequence of this gene is 6535 bp, which includes a promoter of 1624 bp, a terminator of 642 bp and a coding region of 4264 bp. The promoter contains many of the potential transcription factor binding sites found in the 5’ upstream region of the ech42 gene of T. atroviride P1. These included: heat shock factors (HSF), a nitrogen-regulating factor (Nit-2), a stress-response element (STRE), a GCR1 elements, and a Cre BP1 motif. Northern analysis and RT-PCR demonstrated that TABC2 is highly expressed when Trichoderma is subjected to nitrogen starvation, grown in the presence of culture filtrates of Botrytis cinerea, Rhizoctonia solani, and Pythium ultimum, or when N-acetylglucosamine is added to the substrate. TABC2 appears to be co-regulated with some CWDE-encoding genes, suggesting that this is the first ABC transporter encoding gene involved in mycoparasitic events. It’s role in the interaction of Trichoderma with fungal hosts or plants is being investigated by targeted gene disruption and overexpression. | Lanzuise S Ruocco M Scala V Catapano L Woo S Ciliento R Ferraioli S Soriente I Vinale F Scala F Del Sorbo G Lorito M | 2004 | 浙江大学学报(农业与生命科学版)2004，30，4： | 2 |
| 2 | Handling Motion-Blur in 3D Tracking and Rendering for Augmented Reality 显示文摘 | Park Y Lepetit V Woo W | 2012 | IEEE Transactions on Visualization and Computer Graphics2012，18，9： | 1 |
| 3 | Inhibition of matrix metalloproteinase activity by TIMP - 1 gene transfer effectively treats ischemic cardiomyopathy显示文摘 | Jayasankar V Woo YJ Bish LT | 2004 | Circulation2004，110，11： | 1 |
| 4 | Scalable real-time planar targets tracking for digilog books显示文摘 | Kim K Lepetit V Woo W | 2010 | The Visual Computer2010，26，11： | 1 |
| 5 | De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury显示文摘 | Gerzanich V Woo SK Vennekens R | 2009 | Nat Med2009，15，2： | 1 |
| 6 | The tunnel source(PNPN)n-MOSFET:a novel high performance transistor显示文摘 | NAGAVARAPU V JHAVERI R WOO J C S | 2008 | IEEE Transactions on Electron Devices2008，55，4： | 1 |
| 7 | Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes 显示文摘 | List JF Woo V | 2009 | Diabetes Care2009，32，4： | 1 |
| 8 | Steroid sulfatase: a pivotal player in estrogen synthesis and metabolism 显示文摘 | Purohit A Woo L L Potter B V | 2011 | Molecular and Cellular Endocrinology2011，340，15： | 1 |
| 9 | Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection显示文摘 | Cheng V C C Lau S K P Woo P C Y | 2007 | Clin Micrnbiol Rev2007，20，4： | 1 |
| 10 | Recent advancements of flow cytometry:new applications in hematology and oncology显示文摘 | WOO J BAUMANN A ARGUELLO V | 2014 | Expert Rev Mol Diagn2014，14，1： | 1 |
| 11 | A new heuristic optimization algorithm:harmony search 显示文摘 | Zong Woo Geem Joong Hoon Kim Loganathan G V | 2001 | Simulation2001，76，2： | 1 |
| 12 | Dapagliflozin in patients with type 2 diabetes receiving high doses of insulin: efficacy and safety over 2 years显示文摘 | Wilding JP Woo V Rohwedder K | 2014 | Diabetes Obes Metab2014，16，2： | 1 |
| 13 | Inhibition of matrix metalloproteinase activity by TIMP-1 gene transfer effectively treats ischemic cardiomyopathy显示文摘 | Jayasankar V Woo J Bish L | 2004 | Circulation2004，110，11： | 1 |
| 14 | Regulation of hippocampal synaptic plasticity by cyclic AMP dependent protein kinases显示文摘 | Nguyen P V Woo N H | 2003 | Prog Neurobiol2003，71，6： | 1 |
| 15 | Dapagliflozin: where does it fit in the treatment of type 2 diabetes 显示文摘 | WOO V C | 2009 | Expert Opin Phar- macother2009，10，15： | 1 |
| 16 | Long-term efficacy of dapagliflozin in patients with type 2 diabetes mellitus receiving high doses of insulin : a randomizedtrial显示文摘 | Wilding JP Woo V | 2012 | Ann Intern Med2012，6，： | 1 |
| 17 | Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes显示文摘 | List JF Woo V Morales E | 2009 | Diabetes Care2009，32，4： | 1 |
| 18 | Sodium-glucose cotransport inhibition with dapaglifiozin in type 2 diabetes显示文摘 | List JF Woo V Morales E | 2009 | Diabetes Care2009，32，4： | 1 |
| 19 | Ruthenium and gold-doped M1 phase MoVNbTeO catalysts for propane ammoxidation to acrylonitrile显示文摘 | Biswas P Woo J Guliants V V | 2010 | Catalysis Communications2010，12，1： | 1 |
| 20 | Dapagliflozin in patients with type 2 diabetes receiving high doses of insulin: efficacy and safety over 2 years 显示文摘 | Wilding JP Woo V | 2013 | Diabetes Obes Metab2013，16，2： | 1 |
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