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| 1 | miR-27b inhibits gastric cancer metastasis by targeting NR2F2显示文摘增加的注意在癌症过程集中于 miRNAs 的下面规定。原子受体亚科 2 (NR2F2,也作为 COUP-TFII 知道) 涉及癌症的许多类型的发展,但是它在胃的癌症的角色留下逃犯。在这个实验, oncomine 和 Kaplan-meier 数据库表明 NR2F2 在胃的癌症是起来调整的并且高 NR2F2 表示贡献了差的幸存。MicroRNA-27b 被指向并且由在人的胃的癌症纸巾和房间的 NR2F2 下面调整。miR-27b 的宫外的表示在 vitro 并且在 vivo 禁止了胃的癌症房间增长和肿瘤生长。试金建议 miR-27b 的 overexpression 能支持 MGC-803 房间移植和侵略并且延迟他们的转移到肝。另外, miR-27b 的下面规定在 vitro 提高了 GES-1 房间增长和转移。这些调查结果表明 miR-27b 为改进病人是在胃的癌症和 biomarker 的肿瘤 suppressor 幸存。 | Qingzhao Feng Xionglin Wu Fuchao Li Beibei Ning Xiaofeng Lu Yin Zhang Ying Pan Wenxian Guan | 2017 | Protein & Cell2017，8，2： | 16 |
| 2 | Syringaresinol-4-O-β-D-glucoside alters lipid and glucose metabolism in HepG2 cells and C2C12 myotubes显示文摘Syringaresinol-4-O-β-D-glucoside(SSG), a furofuran-type lignan, was found to modulate lipid and glucose metabolism through an activity screen of lipid accumulation and glucose consumption, and was therefore considered as a promising candidate for the prevention and treatment of metabolic disorder,especially in lipid and glucose metabolic homeostasis. In this study, the effects of SSG on lipogenesis and glucose consumption in Hep G2 cells and C2C12 myotubes were further investigated. Treatment with SSG significantly inhibited lipid accumulation by oil red O staining and reduced the intracellular contents of total lipid, cholesterol and triglyceride in Hep G2 cells. No effect was observed on cell viability in the MTT assay at concentrations of 0.1–10 μmol/L. SSG also increased glucose consumption by Hep G2 cells and glucose uptake by C2C12 myotubes. Furthermore, real-time quantitative PCR revealed that the beneficial effects were associated with the down-regulation of sterol regulatory element-binding proteins-1c,-2(SREBP-1c,-2), fatty acid synthase(FAS), acetyl CoA carboxylase(ACC) and hydroxyl methylglutaryl CoA reductase(HMGR), and up-regulation of peroxisome proliferator-activated receptors alpha and gamma(PPARα and PPARγ). SSG also significantly elevated transcription activity of PPARγtested by luciferase assay. These results suggest that SSG is an effective regulator of lipogenesis and glucose consumption and might be a candidate for further research in the prevention and treatment of lipid and glucose metabolic diseases. | Shuai Wang Chongming Wu Xin Li Yue Zhou Quanyang Zhang Fuchao Ma Jianhe Wei Xiaopo Zhang Peng Guo | 2017 | Acta Pharmaceutica Sinica B2017，7，4： | 3 |
| 3 | Robust line matching through line-point invariants 显示文摘 | Fan Bin Wu Fuchao Hu Zhangyi | 2012 | Pattern Recognition2012，45，2： | 1 |
| 4 | A note on the conver-gence of the mean shift显示文摘 | Li Xiangru Hu Zhanyi Wu Fuchao | 2007 | Elsevier Science2007，40，6： | 1 |
| 5 | Towards reliable matching of images containing repetitive patterns显示文摘 | Bin Fan Fuchao Wu Zhanyi Hu | 2011 | Pattern Recognition Letters2011，，14： | 1 |
| 6 | MSLD: A robust descriptor for line matching显示文摘 | Zhiheng Wang Fuchao Wu Zhanyi Hu | 2008 | Pattern Recognition2008，，5： | 1 |
| 7 | implementation and Experimental Study on Fast Object Modeling Based on Multiple Structured Stripes显示文摘 | Wang Guanghui Hu Zhanyi Wu Fuchao | 2004 | Optics and Lasers in Engineering2004，，6： | 1 |
| 8 | Single view metrology from scene constraints显示文摘 | Wang Guanghui Hu Zhanyi Wu Fuchao | 2005 | Image and Vision Computing2005，23，9： | 1 |
| 9 | Single view metrology from scene constraints显示文摘 | Wang Guanghui Hu ghanyi Wu Fuchao | 2005 | Image and Vision Computing2005，23，9： | 1 |
| 10 | Rotationally invariant descriptors using intensity order pooling显示文摘 | Fan Bin Wu Fuchao Hu Zhanyi | 2012 | IEEE Trans on Pattern Analysis and Machine Intelligence2012，34，10： | 1 |
| 11 | MSLD:a robust descriptor for line matching显示文摘 | WANG Zhiheng WU Fuchao HU Zhanyi | 2009 | Pattern Recognition2009，42，5： | 1 |
| 12 | Coplanar circles,quasi-affine invariance and calibration显示文摘 | Wu Yihong Li Xinju Wu Fuchao | 2006 | Image and Vision Computing2006，24，4： | 1 |
| 13 | Robust line matching through line-point invariants显示文摘 | FAN Bin WU Fuchao HU Zhanyi | 2012 | Pattern Recognition2012，45，2： | 1 |
| 14 | A note on the conver-gence of the mean shift显示文摘 | Li Xiangru Hu Zhanyi Wu Fuchao | 2007 | Elsevier Science2007，40，： | 1 |
| 15 | Rotationally invariant descriptors using intensity order pooling显示文摘 | Fan Bin Wu Fuchao Hu Zhanyi | 2012 | IEEE Transactions on Pattern Analysis and Machine Intelligence2012，34，10： | 1 |
| 16 | A new linear algorithm for calibrating central eatadioptric cameras 显示文摘 | Wu Fuchao Duan Fuqing Hu Zhanyi | 2008 | Pattern Recognition2008，41，10： | 1 |
| 17 | Camera calibration with moving one-dimensional objects显示文摘 | Wu Fuchao Hu Zhanyi Zhu Haijiang | 2005 | Pattern Recognition2005，38，5： | 1 |
| 18 | Euclid- ean reconstruction of a circular truncated cone only from its uncele- brated contours显示文摘 | WU YIHONG WANG GUANGHUI WU FUCHAO | 2006 | hnage and Vision Computing2006，24，8： | 1 |
| 19 | A note on the convergence of the mean shift显示文摘 | LI Xiangru HU Zhanyi WU Fuchao | 2007 | Pattern Recognition2007，40，6： | 1 |
| 20 | Rotationally invariant descriptors using intensity order pooling显示文摘 | FAN Bin WU Fuchao HU Zhanyi | 2012 | IEEETrans on Pattern Analysis and Machine Intelligence2012，34，10： | 1 |
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