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| 1 | Consensus on the digestive endoscopic tunnel technique显示文摘With the digestive endoscopic tunnel technique(DETT), many diseases that previously would have been treated by surgery are now endoscopically curable by establishing a submucosal tunnel between the mucosa and muscularis propria(MP). Through the tunnel, endoscopic diagnosis or treatment is performed for lesions in the mucosa, in the MP, and even outside the gastrointestinal(GI) tract.At present, the tunnel technique application range covers the following:(1)Treatment of lesions originating from the mucosal layer, e.g., endoscopic submucosal tunnel dissection for oesophageal large or circular early-stage cancer or precancerosis;(2) treatment of lesions from the MP layer, per-oral endoscopic myotomy, submucosal tunnelling endoscopic resection, etc.; and(3) diagnosis and treatment of lesions outside the GI tract, such as resection of lymph nodes and benign tumour excision in the mediastinum or abdominal cavity. With the increasing number of DETTs performed worldwide, endoscopic tunnel therapeutics, which is based on DETT, has been gradually developed and optimized. However, there is not yet an expert consensus on DETT to regulate its indications, contraindications, surgical procedure, and postoperative treatment.The International DETT Alliance signed up this consensus to standardize the procedures of DETT. In this consensus, we describe the definition, mechanism,and significance of DETT, prevention of infection and concepts of DETTassociated complications, methods to establish a submucosal tunnel, and application of DETT for lesions in the mucosa, in the MP and outside the GI tract(indications and contraindications, procedures, pre-and postoperative treatments, effectiveness, complications and treatments, and a comparison between DETT and other operations). | Ning-Li Chai Hui-Kai Li En-Qiang Linghu Zhao-Shen Li Shu-Tian Zhang Yu Bao Wei-Gang Chen Philip WY Chiu Tong Dang Wei Gong Shu-Tang Han Jian-Yu Hao Shui-Xiang He Bing Hu1 Bing Hu2 Xiao-Jun Huang Yong-Hui Huang Zhen-Dong Jin Mouen A Khashab James Lau Peng Li Rui Li De-Liang Liu Hai-Feng Liu Jun Liu Xiao-Gang Liu Zhi-Guo Liu Ying-Cai Ma Gui-Yong Peng Long Rong Wei-Hong Sha Pateek Sharma Jian-Qiu Sheng Shui-Sheng Shi Dong Wan Seo Si-Yu Sun Gui-Qi Wang Wen Wang Qi Wu Hong Xu Mei-Dong Xu Ai-Ming Yang Fang Yao Hong-Gang Yu Ping-Hong Zhou Bin Zhang Xiao-Feng Zhang Ya-Qi Zhai | 2019 | World Journal of Gastroenterology2019，25，7： | 5 |
| 2 | Dissolution-facilitating Dislocation Emission, Motion andInitiation of SCC in 310 Stainless Steel显示文摘Using a special constant deflection device, the in situ TEM observations of dislocation emission,motion and the initiation of nanocrack in 310 stainless steel in water were carried out. The results show that SCC in thin foil specimen of 310 stainless steel can occur in water. A nanocrack initiated in the DFZ or at the blunt crack tip in corrosion solution after dislocation emission,multiplication and motion, which were induced by the localized anodic dissolution, reached a critical condition. The nanocrack propagated by a cleavage mode because of the influence of the corrosion solution. | Huang, YH Chen, QZ Chu, WY | 1997 | Journal of Materials Science & Technology1997，13，6： | 2 |
| 3 | Antibacterial effects of N-sulfonated and Nsulfobenzoyl chitosan and application to oyster preservation 显示文摘 | Chen CS Liau WY Tsai GJ | 1998 | J Food Prot1998，61，： | 2 |
| 4 | Optimal cut-off values for obesity:using simple anthropometric indices to predict cardiovascular risk factors in Taiwan显示文摘 | Lee LT Chen CY | 2002 | Int J Obes Relat Metab Disord2002，26，： | 1 |
| 5 | Physical activity' s impact on the association of fat and fiber intake with survival after breast cancer显示文摘 | Holmes MD Chen WY Hankinson SE | 2009 | Am J Epidemiol2009，170，10： | 1 |
| 6 | Physical activityand survival after breast cancer diagnosis 显示文摘 | Holmes MD Chen WY Feskanich D | 2005 | JAMA2005，293，20： | 1 |
| 7 | Implantation of VX2 carcinoma into the liver of rabbits:a comparison of three direct-injection methods显示文摘 | Lin WY Chen J Lin Y | 2002 | Vet Med Sci2002，64，7： | 1 |
| 8 | Insulinoma causing hy-poglycemia in a patient with type 2diabetes显示文摘 | Lei WY Wang TE Chen TL | 2007 | J Formos MedAssoc2007，106，5： | 1 |
| 9 | Tetramethylpyrazine reduces ischemic brain injury in rats显示文摘 | Liao SL Kao TK Chen WY | 2004 | Neurosci Let2004，372，12： | 1 |
| 10 | Collagen type 3 alpha 1 polymorphism and risk of pelvic organ prolapse显示文摘 | Chen HY Chung YW Lin WY | 2008 | Int J Gynaecol Obstet2008，103，1： | 1 |
| 11 | A new technique of hepatic segmen- tectomy by selective portal venous occlusion using a balloon catheter through a branch of the superior mesenteric vein 显示文摘 | Ou JR Chen W Lau WY | 2007 | World J Surg2007，31，6： | 1 |
| 12 | Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses显示文摘 | Chen WY Wang DH Yen RC | 2005 | Cell2005，123，3： | 1 |
| 13 | The volume of retropharyngeal nodes predicts distant metastasis in patients with advanced nasopharyngeal carcinoma 显示文摘 | Chen KW Wang WY Liang WM | 2011 | Oral Oncol2011，47，12： | 1 |
| 14 | Original article pilot screening for fragile X carrier in pregnant women of southern Taiwan显示文摘 | Huang KF Chen WY Tsai YC | 2003 | J Chin Med Assoe2003，66，4： | 1 |
| 15 | Chymase is upregulated in diabetic nephropathy:Implication for an alternative pathway of angiotensin Ⅱ-mediated diabetic renal and vascular disease显示文摘 | Huang XR Chen WY Truong LD | 2003 | J Am Soc Nephrol2003，14，： | 1 |
| 16 | Accelerated 3D T-FDK reconstruction algorithm using the commodity graphics hardware显示文摘 | Dai ZS Chen ZQ Bi WY | 2007 | Journal of Tsinghua University2007，46，07： | 1 |
| 17 | Matrix metalloprotein- ase-9 polymorphism and risk of pelvic organ prolapse in Taiwanese women显示文摘 | Chen HY Lin WY Chen YH | 2010 | Eur J Obstet Gyneeol Reprod Biol2010，149，： | 1 |
| 18 | Urothelial carcinomas arising in arseniccontaminated areas are associated with hypermethylation of the gene promoter of the death-associated protein kinase显示文摘 | Chen WT Hung WC Kang WY | 2007 | Histopathology2007，51，6： | 1 |
| 19 | COX-2 expression predicts worse breast cancer prognosis and does not modify the association with aspirin显示文摘 | Holmes MD Chen WY Schnitt SJ | 2011 | Breast Cancer Res Treat2011，130，2： | 1 |
| 20 | Beneficial effect of docosahexaenoic acid on cholestatic liver injury in rats显示文摘 | Chen WY Lin SY Pan HC | 2012 | J Nutr Biochem2012，23，3： | 1 |
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