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| 1 | Hepatitis B virus genotypes and lamivudine resistance mutations in Jordan显示文摘AIM:To investigate and identify prevalent hepatitis B virus(HBV) genotypes and to explore lamivudine-resistant mutations among treated and untreated patients in Jordan.METHODS:A total of 107 cases with chronic hepatitis B were recruited from different medical centers in Jordan.Serological tests were preformed for all cases using a microparticle enzyme immunoassay.HBV Genotyping was performed for 70 cases using Line probe genotyping assay.The YMDD mutations were explored for 20 cases(4 were lamivudine naive) using the INNO-LiPA HBV DR assay.RESULTS:Genotype D was the only detected genotype.A total of 6 YMDD mutations were detected in 5 treated patients(31%) while one mutation was detected in the naive patients.Seventeen percent of cases were positive for HBeAg and had statistically significant higher levels of serum aminotransferases.CONCLUSION:HBV genotype D appears to be the only circulating type in Jordanian patients.The YMDD mutations were detected in 31% of lamivudine-treated cases with similar patterns to those found in the literature.We also found a relatively low prevalence of HBeAg expression among examined cases(17%).Awareness of these serologic,genotypic and resistance patterns might help in the formulation of management plans and for predicting clinical outcomes.Further larger scale studies are needed to confirm our results and to examine possible associations among clinical,serologic,and genetic patterns of HBV infections in Jordan. | Hani A Masaadeh Wail A Hayajneh Enayat A Alqudah | 2008 | World Journal of Gastroenterology2008，14，47： | 10 |
| 2 | Ketamine and midazolam sedation for pediatric gastrointestinal endoscopy in the Arab world显示文摘AIM:To evaluate the safety and effectiveness of intravenous ketamine-midazolam sedation during pediatric endoscopy in the Arab world.METHODS:A retrospective cohort study of all pediatric endoscopic procedures performed between 2002-2008 at the shared endoscopy suite of King Abdullah University Hospital,Jordan University of Science & Technology,Jordan was conducted.All children were > 1 year old and weighed > 10 kg with American Society of Anesthesiologists class 1 or 2.Analysis was performed in terms of sedation-related complications(desaturation,respiratory distress,apnea,bradycar-dia,cardiac arrest,emergence reactions),adequacy of sedation,need for sedation reversal,or failure to complete the procedure.RESULTS:A total of 301 patients(including 160 males) with a mean age of 9.26 years(range,1-18 years) were included.All were premedicated with atropine;and 79.4%(239/301) had effective and uneventful sedation.And 248(82.4%) of the 301 patients received a mean dose of 0.16 mg/kg(range,0.07-0.39) midazolam and 1.06 mg/kg(range,0.31-2.67) ketamine,respectively within the recommended dosage guidelines.Recommended maximum midazolam dose was exceeded in 17.6% patients [34 female(F):19 male(M),P = 0.003] and ketamine in 2.7%(3 M:5 F).Maximum midazolam dose was more likely to be exceeded than ketamine(P < 0.001).Desaturation occurred in 37(12.3%) patients,and was reversible by supplemental oxygen in all except 4 who continue to have desaturation despite supplemental oxygen.Four(1.3%) patients had respiratory distress and 6(2%) were difficult to sedate and required a 3rd sedative;12(4%) required reversal and 7(2.3%) failed to complete the procedure.None developed apnea,bradycardia,arrest,or emergence reactions.CONCLUSION:Ketamine-midazolam sedation appears safe and effective for diagnostic pediatric gastrointestinal endoscopy in the Arab world for children aged > 1 year and weighing > 10 kg without co-morbidities. | Mohamad-Iqbal S Miqdady Wail A Hayajneh Ruba Abdelhadi Mark A Gilger | 2011 | World Journal of Gastroenterology2011，17，31： | 5 |
| 3 | Calibration of Caesium-137 meas urements to provide quantitative erosion rate data 显示文摘 | Wailing D E Quine T A | 1990 | Land Degradation and Rehabilitation1990，2，： | 1 |
| 4 | Mapping of quantitative trait loci for growth and carcass traits in commercial sheep population 显示文摘 | Wailing G A Visscher P M Wilson A D | 2004 | Journal of Animal Science2004，，82： | 1 |
| 5 | Regulation of microtubule stability and mitotic progression by surviving显示文摘 | Giodini A Kallio MJ Wail NR | 2002 | Cancer Res2002，62，9： | 1 |
| 6 | Regulation of microtubule stability and mitotic progression by surviving显示文摘 | Giodini A Kallio M J WaIl N R | 2002 | Cancer Res2002，62，9： | 1 |
| 7 | Regulation of microtubule stability and mitotic progression by surviving显示文摘 | Giodini A Kallio MJ Wail NR | 2002 | J Cancer Res2002，62，9： | 1 |
| 8 | Developmental venous anomaly,cavernous malformation, and capillary' telangiectasia: sperlnim of a singledisease显示文摘 | Ahla A Wail S I) Usrholtl T | 2008 | Af*ta Neurochir(Wien)2008，150，5： | 1 |
| 9 | Mechanisms of Mold Filling in the EPC Process 显示文摘 | Wailing R P Dantzig J A | 1994 | AFS Trans1994，102，： | 1 |
| 10 | A reconnaissance survey of the source of interstitial fine sediment recovered from salmonid spawning gravels in England and Wales 显示文摘 | Wailing D E Collins A L MeMellin G K | 2003 | Hydrobiologia2003，，1： | 1 |
| 11 | Human motion recognition using a wireless senso:based wearable system显示文摘 | Varkey J P Pompili D Wails T A | 2012 | Personal and Ubiauitous Computing2012，16，89： | 1 |
| 12 | Characteristics of transform- er exciting current during geomagnetic disturbances 显示文摘 | Wailing R A Khan A H | 1991 | IEEE Trans Power De[iv1991，6，4： | 1 |
| 13 | Monitoring fluvial pollen transport, its relationship to catchment vegetation and implications for palaeoenvironmental studies 显示文摘 | Brown A G Carpenter R G Wailing D E | 2007 | Review of Palaeobotany and Palynology2007，147，： | 1 |
| 14 | Detection and monitoring of 3 - monochloropropane - 1,2 - diol (3 - MCPD) esters in cooking oils 显示文摘 | RAZNIM A A R AINIE K WAIL S | 2012 | Food Control2012，25，： | 1 |
| 15 | Reliable network de- sign problem: the case with stoehastie demand and total trav- el time reliability 显示文摘 | Sumalec A Wailing D Nakayama S | 2006 | Transportation Research Record2006，1964，： | 1 |
| 16 | The reaction of lower halides ith cyclopentadiene: mono-and dicyclopentadienyl halides of zirconium and titanium 显示文摘 | Wailes P C | 1964 | J Organoment Chem1964，2，4： | 1 |
| 17 | Preparative HPLC Method for the Purification of Sulforaphane and Sulforaphane Nitrile from Brassica Olerecea显示文摘 | Matusheski N V Wailing M A | 2001 | Agricultural and Food Chemistry2001，49，4： | 1 |
| 18 | Continuous hydrogenation of yallourn brown-coal tar显示文摘 | Wailes P C Bell A P Triffett A C K | 1980 | Fuel1980，59，2： | 1 |
| 19 | Migration of FR finishes during drying of cylindrical cotton samples显示文摘 | LYONS D W EL-NASHER A WAIL S L | 1977 | Textile Chemist and Colorist1977，9，5： | 1 |
| 20 | Skin - sparing masteetomy and immediate breast reconstruction: patient satisfaction and clinical outcome显示文摘 | MOHAMED S WAIL A S ANTONY J | 2006 | Int J Clin Oncol2006，11，1： | 1 |
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