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| 1 | Service-aware 6G:An intelligent and open network based on the convergence of communication,computing and caching显示文摘With the proliferation of the Internet of Things(IoT),various services are emerging with totally different features and requirements,which cannot be supported by the current fifth generation of mobile cellular networks(5G).The future sixth generation of mobile cellular networks(6G)is expected to have the capability to support new and unknown services with changing requirements.Hence,in addition to enhancing its capability by 10–100 times compared with 5G,6G should also be intelligent and open to adapt to the ever-changing services in the IoT,which requires a convergence of Communication,Computing and Caching(3C).Based on the analysis of the requirements of new services for 6G,this paper identifies key enabling technologies for an intelligent and open 6G network,all featured with 3C convergence.These technologies cover fundamental and emerging topics,including 3C-based spectrum management,radio channel construction,delay-aware transmission,wireless distributed computing,and network self-evolution.From the detailed analysis of these 3C-based technologies presented in this paper,we can see that although they are promising to enable an intelligent and open 6G,more efforts are needed to realize the expected 6G network. | Yiqing Zhou Ling Liu Lu Wang Ning Hui Xinyu Cui Jie Wu Yan Peng Yanli Qi Chengwen Xing | 2020 | Digital Communications and Networks2020，6，3： | 57 |
| 2 | Quercetin induces apoptosis by activating caspase-3 and regulating Bcl-2 and cyclooxygenase-2 pathways in human HL-60 cells显示文摘橡黄素是自然地发生之一饮食的黄酮醇混合物。它在植物富有地是在场的并且有 chemopreventive 和 anticancer 效果。调查它的 anticancer 机制,我们对尖锐白血病房间线检验了橡黄素的活动, HL-60。我们的结果证明橡黄素禁止了房间增长并且在一个时间依赖者和剂量依赖者举止导致了 apoptosis。而且,橡黄素下面调整 anti-apoptosis 蛋白质 Bcl-2 的表示并且起来调整 pro-apoptosis 蛋白质 Bax 的表示。Caspase-3 被橡黄素也激活,它开始了一条 caspase-3-depended mitochodrial 小径导致 apoptosis。橡黄素禁止了 cycloocygenase-2 (Cox-2 ) 的表示,这也被发现 mRNA 和 Cox-2 蛋白质。一起拿,这些调查结果建议橡黄素由禁止 Cox-2 表示在一条 caspase-3-dependent 小径导致 apoptosis 并且调整下游的 apoptotic 部件的表示,包括 Bcl-2 和 Bax。橡黄素能是可能安全地在白血病治疗被使用的一个有势力和有希望的药。 | Guomin Niu Songmei Yin Shuangfeng Xie Yiqing Li Danian Nie Liping Ma Xiuju Wang Yudan Wu | 2011 | Acta Biochimica et Biophysica Sinica2011，43，1： | 28 |
| 3 | Repress,on of MYBL2 by Both microRNA858a and HY5 Leads to the Activation of Anthocyanin Biosynthetic Pathway in Arabidopsis显示文摘 | Yulong Wang Yiqing Wang Zhaoqing Song Huiyong Zhang | 2016 | Molecular Plant2016，9，10： | 27 |
| 4 | Non-fragile switching tracking control for a flexible air-breathing hypersonic vehicle based on polytopic LPV model显示文摘This article proposes a linear parameter varying (LPV) switching tracking control scheme for a flexible air-breathing hypersonic vehicle (FAHV). First, a polytopic LPV model is constructed to represent the complex nonlinear longitudinal model of the FAHV by using Jacobian linearization and tensor-product (T-P) model transformation approach. Second, for less conservative controller design purpose, the flight envelope is divided into four sub-regions and a non-fragile LPV controller is designed for each parameter sub-region. These non-fragile LPV controllers are then switched in order to guarantee the closed-loop FAHV system to be asymptotically stable and satisfy a specified performance criterion. The desired non-fragile LPV switching controller is found by solving a convex constraint problem which can be efficiently solved using available linear matrix inequality (LMI) techniques, and robust stability analysis of the closed-loop FAHV system is verified based on multiple Lypapunov functions (MLFs). Finally, numerical simulations have demonstrated the effectiveness of the proposed approach. | Huang Yiqing Sun Changyin Qian Chengshan Wang Li | 2013 | Chinese Journal of Aeronautics2013，26，4： | 19 |
| 5 | On modeling and control of a flexible air-breathing hypersonic vehicle based on LPV method显示文摘这篇文章开发 polytopic 变化的线性参数(LPV ) 模型和礼品为灵活呼吸空气的极超音速的车辆(FAHV ) 的非易碎的 H 2 安排获得的控制。首先, FAHV 的 polytopic LPV 模型能被使用 Jacobian linearization 和张肌产品(TP ) 模型转变途径获得,模拟确认说明 polytopic LPV 模型捕获原来的非线性的系统的本地非线性。基于发达 polytopic LPV 模型,第二,一个非易碎的 gainscheduled 控制方法被建议以便减少在控制器实现遇到的脆弱,有线性矩阵不平等( LMI )的一个凸的优化问题限制为设计速度和高度追踪控制器被提出,它保证 H 2 控制性能索引。最后,数字模拟表明了建议途径的有效性。 | Changyin SUN Yiqing HUANG Chengshan QIAN Li WANG | 2012 | Frontiers of Electrical and Electronic Engineering in China2012，7，1： | 12 |
| 6 | Polytopic LPV modeling and gain-scheduled switching control for a flexible air-breathing hypersonic vehicle显示文摘A novel gain-scheduled switching control method for the longitudinal motion of a flexible air-breathing hypersonic vehicle (FAHV) is proposed.Firstly,velocity and altitude are selected as scheduling variables,a polytopic linear parameter varying(LPV) model is developed to represent the complex nonlinear longitudinal dynamics of the FAHV.Secondly,based on the obtained polytopic LPV model,the flight envelope is divided into four smaller subregions, and four gain-scheduled controllers are designed for these parameter subregions.Then,by the defined switching characteristic function,these gain-scheduled controllers are switched in order to guarantee the closed-loop FAHV system to be asymptotically stable and satisfy a given tracking error performance criterion.The condition of gain-scheduled switching controller synthesis is given in terms of linear matrix inequalities(LMIs) which can be easily solved by using standard software packages.Finally,simulation results show the effectiveness of the presented method. | Yiqing Huang Changyin Sun Chengshan Qian Jingmei Zhang Li Wang | 2013 | Journal of Systems Engineering and Electronics2013，24，1： | 10 |
| 7 | Primarily screening and analyzing ESTs differentially expressed in rats' primary liver cancer显示文摘Objective: To screen and analyze key express sequence tags (ESTs) which were differentially displayed in every period of SD rats' primary hepatic carcinoma and reveal the molecular mechanism of carcinogenesis. Methods: Using diethylnitrosamine (DENA) as a cancerigenic agent, animal models with different phases of primary hepatic cancer were constructed in SD rats. Rats were respectively sacrificed at d 14, d 28, d 56, d 77, d 105 and d 112 after the rats received DENA by gavage, then the livers were harvested. One part of the livers was classified according to their pathological changes, while the other was reserved for molecular mechanism studies on hepatocarcinogenesis. The differentially expressed genes were isolated from both normal and morbid tissues by mRNA differential display technique (DDRT-PCR). After the fragments were sequenced, bioinformatics were used to analyze the results. Results: Twelve differentially expressed cDNA fragments were obtained. Nine fragments had the homology with known cDNA clones, especially EST-7 was similar to BN/SsNHsdMCW mitochondrion gene and the identity was 100% which suggested EST-7 may be the part of BN/SsNHsdMCW mitochondrion gene. In contrast, other three fragments (EST-1, EST-3 and EST-5) had extremely low identity to any genes registered in GENBANK databases. Conclusions: BN/SsNHsdMCW mitochondrion gene was expressed in different periods of hepatocarcinogenesis. Moreover, EST-1, EST-3 and EST-5 were suggested to contribute to the development of rat hepatocarcinogenesis, and thus may be candidates of new targets of oncogenes or cancer suppressor genes. | Dandan Liu Lijuan Zhi Mingxia Ma Dan Qiao Meijuan Wang Yawei Wang Baijie Jin Anqi Li Guting Liu Yiqing Zhang Yanyan Song Hongxu Zhang | 2013 | Chinese Journal of Cancer Research2013，25，1： | 9 |
| 8 | Solidification Structure of Low Carbon Steel Strips with Different Phosphorus Contents Produced by Strip Casting显示文摘在现在的纸,有不同的磷内容的低碳钢脱衣用扔过程的成双的转动脱衣被生产。团结结构被学习,它的特征详细被分析。脱衣与模子铸钢相比拥有了好微观结构,这被发现。与增加磷内容,更多的铁酸盐与更好的谷物被形成了。 | Na LI Zhenyu LIU Yiqing QIU Zhaosen LIN Xianghua LIU Guodong WANG | 2006 | Journal of Materials Science & Technology2006，22，6： | 8 |
| 9 | SKP2 siRNA inhibits the degradation of P27^kip1 and down-regulates the expression of MRP in HL-60/A cells显示文摘S 阶段联系 kinase 的蛋白质 2 (SKP2 ) 基因是肿瘤 suppressor 基因,并且涉及 P27kip1 的调停 ubiquitin 的降级。SKP2 和 P27kip1 影响通过调整白血病房间的增长, apoptosis 和区别继续和白血病的预后。在这研究,我们探索了通过 SKP2 下面规定 HL-60/A 药抵抗逆行的机制。HL-60/A 房间是由有 SKP2 siRNA 的 Amaxa Nucleofector 系统的 nucleofected。Skp2, P27kip1,和多药抵抗的基因和蛋白质表示层次联系了蛋白质(MRP ) 被反向的抄写聚合酶链反应和西方的污点分析分别地决定。房间周期被流动 cytometry 分析。50% 禁止的集中价值在 chemotherapeutics 的不同集中下面根据这些二种房间的死亡率用细胞毒素的分析被计算比较房间的敏感。HL-60/A 房间显示出由抗力移转特征的多药抵抗显型到 adriamycin, daunorubicin,和 arabinosylcytosine,由于 MRP 的表示。我们发现 SKP2 的表示比在 HL-60 房间在 HL-60/A 房间是更高的,但是 P27kip1 的表示更低。而 P27kip1 的蛋白质水平是起来调整的,在由 SKP2 siRNA 的 HL-60/A 房间 nucleofected 的 SKP2 的表示是下面调整的。与在控制组(由控制 siRNA 的 nucleofected ) 的 MRP 表达式水平相比, mRNA 和蛋白质表达式由 SKP2 siRNA 在 HL-60/A 房间 nucleofected MRP 铺平更低,并且后者房间对 adriamycin, daunorubicin,和 arabinosylcytosine 更敏感。下面调整在 G0/G1 阶段的 SKP2 表示和逮捕房间与下面调整的 MRP 改进白血病房间的药敏感表示。 | Jie Xiao Songmei Yin Yiqing Li Shuangfeng Xie Danian Nie Liping Ma Xiuju Wang Yudan Wu Jianhong Feng | 2009 | Acta Biochimica et Biophysica Sinica2009，41，8： | 7 |
| 10 | Regional tectonic deformation setting before the Ms8.1 earthquake in the west of the Kunlun Mountains Pass显示文摘This paper gives a preliminarily study of the regional tectonic deformation setting before the Ms8.1 earthquake that occurred in the west of the Kunlun Mountains Pass; in the study, the data of the velocity field of crustal horizontal movement during 1991-2000 observed by GPS in and around the Qinghai-Tibet block and those of gravity reiteration in 1998 and 2000 were used. Analysis shows that the preparation and occurrence of this large earthquake are related to the horizontal movement and deformation setting in a large region and might be attributed to the block activity on a relatively large scale. Within the Qinghai-Tibet block, the region of left-lateral shear deformation is of a very large extent. This large earthquake occurred right in such a place where the left-lateral shear strain along the fault strike had the highest rate and the planar dilatation strain was tensile, which was on the margin of negative value region of abnormal gravity variation. The regional tectonic deformation setting can help the huge left-lateral strike-slip rupture to develop. | JIANG Zaisen (江在森) ZHANG Xi (张 希) ZHU Yiqing (祝意青) ZHANG Xiaoliang (张晓亮) WANG Shuangxu (王双绪) | 2003 | Science China Earth Sciences2003，46，z2： | 6 |
| 11 | Down-regulation of CEACAM1 in breast cancer显示文摘(CEACAM1 ) Carcinoembryonic 抗原相关的粘附分子 1 是一种类型属于 CEA 家庭的 1 transmembrane glycoprotein,它当在身体液体的也可溶的形式或房间上的膜界限形式出现,被发现了存在。异常 CEACAM1 表示与肿瘤前进被联系并且在许多人的恶意被发现了。增加的兴趣在乳癌被奉献给 CEACAM1 的表示,但是大多数这些调查结果是矛盾的。这研究的目的是详细地在乳癌调查 CEACAM1 表示。用染色的 immunohistochemical,我们发现那 CEACAM1 表情与 noncancerous 胸纸巾相比在乳癌纸巾被减少或输。另外,可溶的 CEACAM1 在乳癌房间线的文化媒介铺平是比在一个 nontumorigenic 乳房的那些显著地低的上皮的房间线。Immunofluorescence 分析一致地证明乳癌房间线有膜界限 CEACAM1 的相对低的表示。而且, CEACAM1 mRNA 和蛋白质表示层次在分别地用即时反向的 transcriptase 聚合酶链反应和西方的污点分析测量了的乳癌房间线是下面调整的。一起拿,我们的结果在乳癌表明 CEACAM1 的一条系统的下面规定并且建议恢复 CEACAM1 表示的策略可能对乳癌的治疗有用。 | Changcheng Yang Pingqing He Yiwen Liu Yiqing He Cuixia Yang Yan Du Muqing Zhou Wenjuan Wang Guoliang Zhang Man Wu Feng Gao | 2015 | Acta Biochimica et Biophysica Sinica2015，47，10： | 5 |
| 12 | A formulation methodology for multicomponent distillation sequences based on stochastic optimization显示文摘Based on stochastic optimization strategy, a formulation methodology is proposed for synthesizing distillation column sequences, allowing more than one middle component as the distributing components between a pair of key components in the non-sharp split. In order to represent and manipulate the distillation configuration structures, a new coding procedure is proposed in the form of one-dimensional array. Theoretically, an array can represent any kind of split(non-sharp and sharp). With the application of a binary sort tree approach, a robust flow sheet encoding and decoding procedure is developed so that the problem formulation and solution becomes tractable. In this paper,the synthesis problem is formulated as a mixed-integer nonlinear programming(MINLP) problem and an improved simulated annealing approach is adopted to solve the optimization problem. Besides, a shortcut method is applied to the evaluation of all required design parameters as well as the total function. | Fei Wang Yiqing Luo Xigang Yuan | 2016 | Chinese Journal of Chemical Engineering2016，24，9： | 5 |
| 13 | Optimization of the Tuned Mass Damper for Chatter Suppression in Turning显示文摘The tuned mass damper(TMD) has been successfully applied to the vibration control in machining,while the most widely adopted tuning is equal peaks,which splits the magnitude of the frequency response function(FRF) into equal peaks.However,chatter is a special self-excited problem and a chatter-free machining is determined by FRF at the cutting zone.A TMD tuning aiming at achieving the maximum chatter stability is studied,and it is formulated as an optimization problem of maximizing the minimum negative real part of FRF.By employing the steepest descend method,the optimum frequency and damping ratio of TMD are obtained,and they are compared against the equal peaks tuning.The advantage of the proposed tuning is demonstrated numerically by comparing the minimum point of the negative real part,and is further verified by damping a flexible mode from the fixture of a turning machine.A TMD is designed and placed on the fixture along the vibration of the target mode after performing modal analysis and mode shape visualization.Both of the above two tunings are applied to modify the tool point FRF by tuning TMD respectively.Chatter stability chart of the turning shows that the proposed tuning can increase the critical depth of cut 37% more than the equal peaks.Cutting tests with an increasing depth of cut are conducted on the turning machine in order to distinguish the stability limit.The tool vibrations during the machining are compared to validate the simulation results.The proposed damping design and optimization routine are able to further increase the chatter suppression effect. | YANG Yiqing LIU Qiang WANG Min | 2010 | Chinese Journal of Mechanical Engineering2010，23，6： | 5 |
| 14 | Thrombolysis with alteplase 3-4.5 hours after acute ischaemic stroke:the first multicentre,phase III trial in China显示文摘background and purpose Data on the efficacy and safety of alteplase for acute ischaemic stroke(AIS)administered 3-4.5 hours after the onset of stroke symptoms in Chinese patients is limited.We sought to determine whether AIS patients would benefit from thrombolysis with alteplase between 3 and 4.5 hours after the onset of stroke symptoms in a prospective,multicentre,single-arm trial in China.Materials and methods Eligible AIS patients were given 0.9 mg/kg alteplase intravenously.The primary efficacy endpoint was a favourable outcome at 3 months,defined as a score of 0 or 1 on the modified Rankin Scale.Thresholds for the primary efficacy endpoint were determined to be 40%based on the literature review.The primary safety endpoint was symptomatic intracranial haemorrhage(sICH)according to the European Cooperative Acute Stroke Study III(ECASS III)trial definition.Post hoc analysis between this study and the ECASS III trial were compared using the propensity score matching(PSM)method.results A total of 120 eligible AIS patients from 11 sites in China received thrombolysis therapy in this study.The median time from onset of symptoms to needle was 3 hours 54 min.The percentage of patients with a favourable outcome was 63.3%(95%CI 54.4 to 71.4),significantly higher than the predefined threshold(p<0.0001).Three patients(2.5%,95%CI 0.5 to 7.1)had sICH,including two fatal sICH.Six patients died within 3 months after treatment.The post hoc PSM analysis showed a numerically higher rate of the primary efficacy endpoint in this study(63.3%)than the matched placebo arm(56.7%)in the ECASS III trial.Conclusions Intravenous alteplase with a standard dose administered between 3 and 4.5 hours after onset of symptoms is effective and safe for Chinese AIS patients. | Huaguang Zheng Yi Yang Huisheng Chen Chuanling Li Yangkun Chen Fu-Dong Shi Li Yang Xiaoping Cui Zuneng Lu Yanling Liang Songbiao Cui Anding Xu Yiqing Wu Yaqing Sun Yongjun Wang | 2020 | Stroke & Vascular Neurology2020，5，3： | 4 |
| 15 | Organellar genome assembly methods and comparative analysis of horticultural plants显示文摘Although organellar genomes(including chloroplast and mitochondrial genomes)are smaller than nuclear genomes in size and gene number,organellar genomes are very important for the investigation of plant evolution and molecular ecology mechanisms.Few studies have focused on the organellar genomes of horticultural plants.Approximately 1193 chloroplast genomes and 199 mitochondrial genomes of land plants are available in the National Center for Biotechnology Information(NCBI),of which only 39 are from horticultural plants.In this paper,we report an innovative and efficient method for high-quality horticultural organellar genome assembly from next-generation sequencing(NGS)data.Sequencing reads were first assembled by Newbler,Amos,and Minimus software with default parameters.The remaining gaps were then filled through BLASTN search and PCR.The complete DNA sequence was corrected based on Illumina sequencing data using BWA(Burrows–Wheeler Alignment tool)software.The advantage of this approach is that there is no need to isolate organellar DNA from total DNA during sample preparation.Using this procedure,the complete mitochondrial and chloroplast genomes of an ornamental plant,Salix suchowensis,and a fruit tree,Ziziphus jujuba,were identified.This study shows that horticultural plants have similar mitochondrial and chloroplast sequence organization to other seed plants.Most horticultural plants demonstrate a slight bias toward A+T rich features in the mitochondrial genome.In addition,a phylogenetic analysis of 39 horticultural plants based on 15 protein-coding genes showed that some mitochondrial genes are horizontally transferred from chloroplast DNA.Our study will provide an important reference for organellar genome assembly in other horticultural plants.Furthermore,phylogenetic analysis of the organellar genomes of horticultural plants could accurately clarify the unanticipated relationships among these plants. | Xuelin Wang Feng Cheng Dekai Rohlsen Changwei Bi Chunyan Wang Yiqing Xu Suyun Wei Qiaolin Ye Tongming Yin Ning Ye | 2018 | Horticulture Research2018，5，1： | 4 |
| 16 | into the Role of Additives in Catalytic Synthesis of Insight Cyclohexylamine from Nitrobenzene显示文摘Cyclohexylamine is a versatile intermediate in various chemical industries,which can be expediently synthesized via hydrogenation of aniline or nitrobenzene.However,such processes always suffer from side reactions.Many reports have found that specific additives can suppress the formation of side products,but the mechanism is still not clear.In this work,results suggest that it is the hydroxide ion of alkali metal hydroxides,rather than the cations,which plays a key role in suppressing the side reactions on supported Ru-based catalysts.With the assistance of LiOH,the selectivity toward cy- clohexylamine increased from 85.4% to 100%.Side products,such as dicyciohexylamine,cyclohexanol and N-isopropyl cyclohexylamine,could no longer be detected.Theoretical calculations further disclosed that addition of alkali metal hydroxides inhibited the dissociation of enamine and decreased the adsorption energy of cyclohexylamine,which might be the reasons for a better selectivity.However,the addition of alkali metal hydroxides reduced the activity of nitrobenzene hydrogenation by unfolding the condensation reaction route.To recover or even further enhance the catalytic performance,a second metal component was introduced and the resultant RuNi/AC exhibited a significant improvement in activity compared with Ru/AC. | Xuefeng Li Zhe Wang Shanjun Mao Yiqing chen Minghui Tang Haoran Li Yong Wang | 2018 | Chinese Journal of Chemistry2018，36，12： | 4 |
| 17 | Heteroatom-doped porous carbon from methyl orange dye wastewater for oxygen reduction显示文摘Banana peel-derived porous carbon(BPPC) was prepared from banana peel and used as an adsorbent for methyl orange(MO) wastewater removal. BPPC-MO50 is a N,S-doped BPPC obtained via secondary carbonization. The BPPC-MO50 exhibited a high specific surface area of1774.3 m^2/g. Heteroatom-doped porous carbon(PC) was successfully synthesized from the BPPC absorbed MO at high temperature and used for oxygen reduction. The BPPC-MO50 displayed the highest ORR onset potential among all carbon-based electrocatalysts, i.e., 0.93 V vs.reversible hydrogen electrode(RHE). This is the first report to describe porous carbon-activated materials from agriculture and forestry waste that is used for adsorption of dyes from wastewater via an enhanced heteroatom(N,S) content. These results may contribute to the sustainable development of dye wastewater treatment by transforming saturated PC into an effective material and has potential applications in fuel cells or as energy sources. | Yiqing Wang Mingyuan Zhu Yingchun Li Mengjuan Zhang Xueyan Xue Yulin Shi Bin Dai Xuhong Guo Feng Yu | 2018 | Green Energy & Environment2018，3，2： | 4 |
| 18 | Mutations in TP53, ZNF750, and RB1 typify ocular sebaceous carcinoma显示文摘Sebaceous carcinoma (SC) of the eyelid is a rare but aggressive malignancy, accounting for 3%—5% of eyelid malignancies in the United States, and up to 35% in Asian populations (Deprez and Uffer, 2009;Xu et al., 2018;Yu et al., 2018). It is frequently mistaken for benign conditions or less aggressive malignancies such as basal cell carcinoma (Muqit et al., 2013), and the effects of delay in diagnosis can be devastating to patients. Aggressive surgical resection is the primary treatment of these tumors and often invoIves orbital exenteration with significant morbidity to patients, and these tumors frequently recur, with local recurrence rate as high as 18%. Importantly, this disease has a high metastatic potential, and there are very limited data guiding systemic treatment options;ultimately 6%—18% of patients diagnosed with SC of the eyelid succumb to metastatic disease (Zurcher et al., 1998;Shields et al., 2004). | Yongyang Bao J. Eva Selfridge Janet Wang Yiqing Zhao Junqi Cui Kishore Guda Zhenghe Wang Yanbo Zhu | 2019 | Journal of Genetics and Genomics2019，46，6： | 4 |
| 19 | The genome of Magnolia biondii Pamp. provides insights into the evolution of Magnoliales and biosynthesis of terpenoids显示文摘Magnolia biondii Pamp.(Magnoliaceae,magnoliids)is a phylogenetically,economically,and medicinally important ornamental tree species widely grown and cultivated in the north-temperate regions of China.Determining the genome sequence of M.biondii would help resolve the phylogenetic uncertainty of magnoliids and improve the understanding of individual trait evolution within the Magnolia genus.We assembled a chromosome-level reference genome of M.biondii using~67,~175,and~154Gb of raw DNA sequences generated via Pacific Biosciences single-molecule real-time sequencing,10X Genomics Chromium,and Hi-C scaffolding strategies,respectively.The final genome assembly was~2.22Gb,with a contig N50 value of 269.11 kb and a BUSCO complete gene percentage of 91.90%.Approximately 89.17%of the genome was organized into 19 chromosomes,resulting in a scaffold N50 of 92.86Mb.The genome contained 47,547 protein-coding genes,accounting for 23.47%of the genome length,whereas 66.48%of the genome length consisted of repetitive elements.We confirmed a WGD event that occurred very close to the time of the split between the Magnoliales and Laurales.Functional enrichment of the Magnolia-specific and expanded gene families highlighted genes involved in the biosynthesis of secondary metabolites,plant–pathogen interactions,and responses to stimuli,which may improve the ecological fitness and biological adaptability of the lineage.Phylogenomic analyses revealed a sister relationship of magnoliids and Chloranthaceae,which are sister to a clade comprising monocots and eudicots.The genome sequence of M.biondii could lead to trait improvement,germplasm conservation,and evolutionary studies on the rapid radiation of early angiosperms. | Shanshan Dong Min Liu Yang Liu Fei Chen Ting Yang Lu Chen Xingtan Zhang Xing Guo Dongming Fang Linzhou Li Tian Deng Zhangxiu Yao Xiaoan Lang Yiqing Gong Ernest Wu Yaling Wang Yamei Shen Xun Gong Huan Liu Shouzhou Zhang | 2021 | Horticulture Research2021，8，1： | 4 |
| 20 | PulseNet China,a model for future laboratory-based bacterial infectious disease surveillance in China显示文摘Surveillance is critical for the prevention and control of infectious disease.China’s real-time web-based infectious disease reporting system is a distinguished achievement.However,many aspects of the current China Infectious Disease Surveillance System do not yet meet the demand for timely outbreak detection and identification of emerging infectious disease.PulseNet,the national molecular typing network for foodborne disease surveillance was first established by the Centers for Disease Control and Prevention of the United States in 1995 and has proven valuable in the early detection of outbreaks and tracing the pathogen source.Since 2001,the China CDC laboratory for bacterial pathogen analysis has been a member of the PulseNet International family;and has been adapting the idea and methodology of PulseNet to develop a model for a future national laboratory-based surveillance system for all bacterial infectious disease.We summarized the development progress for the PulseNet China system and discussed it as a model for the future of China’s national laboratory-based surveillance system. | Wei Li Shan Lu Zhigang Cui Jinghua Cui Haijian Zhou Yiqing Wang Zhujun Shao Changyun Ye Biao Kan Jianguo Xu | 2012 | Frontiers of Medicine2012，6，4： | 4 |
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