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| 1 | Deepening trochleoplasty combined with balanced medial patellofemoral ligament reconstruction for an adequate graft tensioning显示文摘AIM To evaluate our modified deepening trochleoplasty com-bined with a balanced medial patellofemoral ligament(MPFL) reconstruction for soft tissue alignement. METHODS Thirty-three knees with with recurrent patellar dislocations and a trochlear dysplasia in 30 patients(m/f = 12/21, mean age 24 ± 9 years) underwent a combination of a modified deepening trochleoplasty and a balanced MPFL reconstruction for a medial soft tissue alignement. After a mean follow-up period of 29 ± 23 mo, patients' return to sports, possible complications as well as the clinical outcomes using the Kujala, International Knee Documentation Committee(IKDC) and Lysholm scoring were evaluated. Moreover, patients' satisfaction with the general outcome, the cosmetic outcome, the pre-and postoperative pain and a potential avoidance behaviour were assessed with additional standardized questionnaires which also included different visual analog scales. RESULTS There were no signs of a persistent instability. The Kujala score improved from a mean of 64 ± 16 points to 94 ± 9 points, the Lysholm score improved from a mean of 63 ± 17 to 95 ± 6 points and the IKDC score from 58 ± 11 to 85 ± 12 points, P < 0.0001, respectively. The assessment of pain using a visual analog scale showed a significant pain reduction from a mean of 4.8 ± 2.0 to 1.3 ± 3.4 points(P < 0.0001). Two of 26 cases(92%) who were engaged in regular physical activity before surgery did not return to full sporting activities. One patient felt that his sport was too risky for his knee and reported an ongoing avoidance behaviour. The other patient preferred to wait for surgery of her contralateral knee. Of the eight patients who were not engaged in sporting activities before surgery, three started regular sporting activities after surgery. In 31 of the 33 cases(94%), the patients were very satisfied with the clinical outcome of the surgery. Regarding the cosmetic results, no patients felt impaired in their self-confidence and in their clothing decisions. CONCLUSION Our technique shows a good clinical outcome in terms of the common scorings as well as in terms of pain, return to sports and patient satisfaction. | Lars V von Engelhardt Pia Weskamp Matthias Lahner Gunter Spahn Joerg Jerosch | 2017 | World Journal of Orthopedics2017，8，12： | 2 |
| 2 | Distinct roles for ADAM 10and ADAM 17 in ectodomain shedding of six EGFR ligands 显示文摘 | Sahin U Weskamp G Kelly K | 2004 | JCell Biol2004，64，5： | 1 |
| 3 | Nerve growth factor and its low affinity receptor promote Schwann cell Mgration显示文摘 | ANTON E S WESKAMP G REICHARDT L F | 1994 | Proc Nail Acad Sci USA1994，91，7： | 1 |
| 4 | Nerve growth factor and its low-affinity receptor promote Schwann cell migration 显示文摘 | Anton ES Weskamp G Reichardt LF | 1994 | Proc Natl Acad Sci USA1994，91，7： | 1 |
| 5 | Characterization of the increase in (i) during hypotonic shock and the involvement of Ca^(2+ )-activated K^( + )channels in the regulatory volume decrease in human osteoblast-like cells 显示文摘 | Weskamp M Seidl W Grissmer S | 2000 | J Membr Biol2000，178，： | 1 |
| 6 | Pathological neovascularization is reduced by inactivation of ADAMI7 in endothelial cells but not in perieytes 显示文摘 | Weskamp G Mendelson K Swendeman S | 2010 | Circ Res2010，106，5： | 1 |
| 7 | Nheterocyclic carbenes:novel ruthenium-alkylidene complexes显示文摘 | HERRMANN W A WESKAMP TH KOHL F J | 1999 | J Organomet Chem1999，582，： | 1 |
| 8 | Potential role for ADAM15 in pathological neovascularization in mice显示文摘 | Horiuchi K Weskamp G Lum L | 2003 | Mol Cell Biol2003，23，16： | 1 |
| 9 | Fimbria-fomix lesion increases nerve growth factor content in adult rat septum and hippocampus 显示文摘 | Weskamp G Gasser UE Dravid AR | 1986 | Neurosci Lett1986，70，1： | 1 |
| 10 | Nerve growth factor and its low-affinity receptor promote Schwann cell migration显示文摘 | Anton ES Weskamp G Reichardt LF | 1994 | Proc Natl Acad Sci USA1994，91，： | 1 |
| 11 | Fimbria-fornix lesion increases nerve growth factor content in adult rat septum and hippocampus显示文摘 | Weskamp G Gasser UE Dravid AR | 1986 | Neurosci Lett1986，70，1： | 1 |
| 12 | A sensitive method to monitor ectodomain shedding of ligands of the epidermal growth factor receptor显示文摘 | Sahin U Weskamp G Zheng Y | 2006 | Methods Mol Biol2006，327，： | 1 |
| 13 | Essential role for ADAM19 in cardiovascular morphogenesis显示文摘 | Zhou Hongming Weskamp G Chesneau V | 2004 | Mol Cell Biol2004，24，： | 1 |
| 14 | Nerve growth factor and its low affinity receptor promote Schwann cell mi- gration 显示文摘 | Anton ES Weskamp G Reichardt LF | 1994 | ProcNatlAcadSciUSA1994，91，： | 1 |
| 15 | Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligand显示文摘 | SAHIN U WESKAMP G | 2004 | J Cell2004，64，5： | 1 |
| 16 | ADAMIO is a principal 'shed- dase' of the low-affinity immunoglobulin E receptor CD23 显示文摘 | Weskamp G Ferd JW Sturgill J el al | 2006 | Nat Immunol2006，7，12： | 1 |
| 17 | An enzyme -linked immunoassay for nerve growth factor (NGF), a tool for studying regulatory mechanism involved in NGF production in brain and in peripheral tissues 显示文摘 | Weskamp G Otten U | 1987 | Neurochemistry1987，48，： | 1 |
| 18 | Nerve Growth Factor and Its Low Affinity Receptor Promote Schwann Cell Migration显示文摘 | Anton E S Weskamp G Reichardt L F | 1994 | PNAS1994，91，7： | 1 |
| 19 | Nerve growth factor and its low-affinity receptor promote Schwann cell migration显示文摘 | Anton ES Weskamp W Reichardt LF | 1994 | Proc Natl Acad Sci USA1994，91，： | 1 |
| 20 | Distinct roles for ADAM10 and ADAM-17 in ectodomain shedding of six EGFR-ligands显示文摘 | Sahin U Weskamp G Kelly K | 2004 | J Cell Biol2004，164，5： | 1 |
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