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| 1 | Association of farnesyl diphosphate synthase polymorphisms and response to alendronate treatment in Chinese postmenopausal women with osteoporosis显示文摘 | Liu Y Li M Zhou PR Xing XP Xia WB Xu L Liu H J Zhang ZL LiaoEY Chen DC Liu J Tao TZ Wu W | 2014 | Chinese Medical Journal2014，，4： | 16 |
| 2 | Polymorphisms of MTHFD,plasma homocysteine levels, and risk of gastric cancer in ahigh-risk Chinese population显示文摘Purpose:Accumulative evidence suggests that folate has a protective effect on gastric cancer. The methylenetetrahyd-rofolate dlehydrogenase(MTHFD) plays an important role in folate and homocysteine metabolisms, and polymorphisms of MTHFD may result in disturbance of the folate-mediated homocysteine pathway. The aim of this study is to test the hypothesis that genetic variants of MTHFD and plasma homocysteine levels are associated with risk of gastric cancer and modulated by genotypes of methylenetetrahydrofolate reductase(MTHFR). Experimental Design: We genotyped G1958A and T401C in MTHFD and C677T in MTHFR and detected total plasma homocysteine(tHcy) levels in a case-control study of 589 gastric cancer cases and 635 cancer-free controls in a high-risk Chinese population. Results:The variant genotypes of MTHFD 1958AA and 401CC were associated with a significantly increased risk of gastric canceradjusted odds ratio(OR), 2.05; 95% confidence interval(95% CI),1.34-3.13 for 1958AA; adjusted OR,1.43; 95% CI,1.14-1.80 for 401CC compared with 1958GG/GA and 401TT/TC genotypes, respectively. Both of the effects were more evident in the subjects carrying MTHFR 677CT/TT genotypes. The average tHcy level was significantly higher in gastric cancer cases than in controls(P < 0.01), and the upper quartile of tHcy (> 13.6 mu mol/L) was associated with an 82% significantly increased risk of gastric cancer, compared with the lowest quartile of tHcy(<= 8.0 pmol/L;adjusted OR,1.82; 95% CI,1.20-2.75). Conclusions:The strong associations between MTHFD variants and the plasma tHcy levels and gastric cancer risk suggest, for the first time, a possible gene-environment interaction between genetic variants of folate-metabolizing genes and high tHcy levels in gastric carcinogenesis. | Wang, L. N Ke, Q Chen, W. S Wang, J. M Tan, Y. F Zhou, Y Hua, Z. L Ding, W. L Niu, J. Y Shen, J Zhang, Z. F Wang, X. R Xu, Y. H Shen, H. B Yi Xing | 2007 | 南京医科大学学报(自然科学版)2007，27，7： | 10 |
| 3 | Optimization of growth and jaceosidin in callus and cell suspension cultures of Saussurea medusa 显示文摘 | Zhao D X Xing J M Li M Y | 2001 | Plant Cell Tiss Org2001，67，： | 2 |
| 4 | Tooth loss and alveolar remodeling in Sinosaurus triassicus (Dinosauria: Theropoda) from the Lower Jurassic strata of the Lufeng Basin, China显示文摘Pathological or traumatic loss of teeth often results in the resorption and remodeling of the affected alveoli in mammals. However, instances of alveolar remodeling in reptiles are rare. A remodeled alveolus in the maxilla of the Chinese theropod Sinosaurus (Lower Jurassic Lower Lufeng Formation) is the first confirmed example of such dental pathology in a dinosaur. Given the known relationship between feeding behavior and tooth damage in theropods (teeth with spalled enamel, tooth crowns embedded in bone) and the absence of dentary, maxillary, and premaxillary osteomyelitis, traumatic loss of a tooth is most likely the cause of alveolar remodeling. Based on the extent of remodeling, the injury and subsequent tooth loss were non-fatal in this individual. | XING LiDa BELL Phil R ROTHSCHILD Bruce M RAN Hao ZHANG JianPing DONG ZhiMing ZHANG Wei CURRIE Philip J | 2013 | Chinese Science Bulletin2013，58，16： | 2 |
| 5 | Time-frequency imaging algorithm for high speed spinning targets in two dis- mensions 显示文摘 | Li J Qiu C W Xing M D Bao Z Yeo T S | 2010 | lET2010，4，6： | 1 |
| 6 | New approaches to prepare nitrogen-doped TiO2 photocatalysts and study on their photocatalytic activities in visible light 显示文摘 | Xing M Y Zhang J L Chen F | 2009 | Applied Catalysis B : Environmental2009，89，34： | 1 |
| 7 | Scale-up analysis for a cho cell culture process in large-scale bioreactors显示文摘 | Xing Z Kenty B M Li Z J | | 0，，04： | 1 |
| 8 | 2013, Antigenic and genetic characterization of a European avian-like H1N1 swine influenza virus from a boy in China in 2011显示文摘 | Qi x Cui L Jiao Y Pan Y Li X Zu R Huo X Wu B Tang F Song Y Zhou M Wang H Cardona C J Xing Z | 2013 | Archives of Virology2013，158，1： | 1 |
| 9 | Ethyl-2-amino-6-bro- mo-6-( 1-cyano-2-ethoxy-2-oxoethyl ) -4H-chromene-3- carboxylate( HA 14-1 ), a prototype small-molecule an- tagonist against antiapoptotic Bcl-2 proteins, decom- poses to generate reactive oxygen species that induce apoptosis显示文摘 | DOSHI J M TIAN D XING C | 2007 | Mol Pharm2007，4，6： | 1 |
| 10 | Inhibition of the tumor necrosis factor-alpha pathway is radioprotective for the lung显示文摘 | Zhang M Qian J Xing X | 2008 | Clin Cancer Res2008，14，6： | 1 |
| 11 | Microbial community structure and metabolic property of biofilms in vermifiltration for liquid-state sludge stabilization using PLFA profiles显示文摘 | Zhao C Xing M Yang J | 2014 | Bioresource Technology2014，，151： | 1 |
| 12 | Constant-power-load system stabilization by passive damping 显示文摘 | CESPEDES M XING L SUN J | 2011 | IEEE Transactions on Power Electronics2011，26，7： | 1 |
| 13 | Review of recent developments in tidal hydrodynamic modeling, I: special models显示文摘 | Davies A M Jones J E Xing J | 1983 | Journal of Hydrattlic Engineering1983，123，4： | 1 |
| 14 | Numerical simulation of semi-solid continuous casting process显示文摘 | Xing S M Zhai Q J | 2001 | Trans Nonferrous Met Soc China2001，11，3： | 1 |
| 15 | En- hanced oligodendrogenesis and recovery of neurological function by erythropoietin after neonatal hypoxic/ischemic brain injury 显示文摘 | Iwai M Stetler RA Xing J Hu X Gao Y Zhang W | 2010 | Stroke2010，，5： | 1 |
| 16 | Preparation and characterization of amino-silane modified superparamagnetic silica nanospheres显示文摘 | Liu X G Ma Z Y Xing J M | 2004 | Journal of Magnetism and Magnetic Materials2004，270，： | 1 |
| 17 | Migration through Resolution Cell Composition in ISAR Imaging显示文摘 | Xing M D Wu R B Lan J Q | 2004 | IEEE Geoscience and Remote Sensing Letters2004，1，2： | 1 |
| 18 | Inhibition of the tumor nec- rosis factor - alpha pathway is radioprotective for the lung 显示文摘 | Zhang M Qian J Xing X | 2008 | Clin Cancer Res2008，14，6： | 1 |
| 19 | Numerical study on rapid solidification of a plasma - sprayed cast iron splat on a high - temperature substrate 显示文摘 | Xing Y Z Wei Q L Hao J M | 2009 | Advanced Materials Research2009，，7982： | 1 |
| 20 | Inhibition of the tumor necrosis factor-alpha pathway is radioprotective for the lung 显示文摘 | Zhang M Qian J Xing X | 2008 | Clin Cancer Res2008，14，6： | 1 |
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