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| 1 | Towards a global One Health index: a potential assessment tool for One Health performance显示文摘Background:A One Health approach has been increasingly mainstreamed by the international community, as it provides for holistic thinking in recognizing the close links and inter-dependence of the health of humans, animals and the environment. However, the dearth of real-world evidence has hampered application of a One Health approach in shaping policies and practice. This study proposes the development of a potential evaluation tool for One Health performance, in order to contribute to the scientific measurement of One Health approach and the identification of gaps where One Health capacity building is most urgently needed.Methods:We describe five steps towards a global One Health index (GOHI), including (i) framework formulation;(ii) indicator selection;(iii) database building;(iv) weight determination;and (v) GOHI scores calculation. A cell-like framework for GOHI is proposed, which comprises an external drivers index (EDI), an intrinsic drivers index (IDI) and a core drivers index (CDI). We construct the indicator scheme for GOHI based on this framework after multiple rounds of panel discussions with our expert advisory committee. A fuzzy analytical hierarchy process is adopted to determine the weights for each of the indicators.Results:The weighted indicator scheme of GOHI comprises three first-level indicators, 13 second-level indicators, and 57 third-level indicators. According to the pilot analysis based on the data from more than 200 countries/territories the GOHI scores overall are far from ideal (the highest score of 65.0 out of a maximum score of 100), and we found considerable variations among different countries/territories (31.8–65.0). The results from the pilot analysis are consistent with the results from a literature review, which suggests that a GOHI as a potential tool for the assessment of One Health performance might be feasible.Conclusions:GOHI—subject to rigorous validation—would represent the world’s first evaluation tool that constructs the conceptual framework from a holistic perspective of One Health. Future application of GOHI might promote a common understanding of a strong One Health approach and provide reference for promoting effective measures to strengthen One Health capacity building. With further adaptations under various scenarios, GOHI, along with its technical protocols and databases, will be updated regularly to address current technical limitations, and capture new knowledge. | Xiao-Xi Zhang Jing-Shu Liu Le-Fei Han Shang Xia Shi-Zhu Li Odel YLi Kokouvi Kassegne Min Li Kun Yin Qin-Qin Hu Le-Shan Xiu Yong-Zhang Zhu Liang-Yu Huang Xiang-Cheng Wang Yi Zhang Han-Qing Zhao Jing-Xian Yin Tian-Ge Jiang Qin Li Si-Wei Fei Si-Yu Gu Fu-Min Chen Nan Zhou Zi-Le Cheng Yi Xie Hui-Min Li Jin Chen Zhao-Yu Guo Jia-Xin Feng Lin Ai Jing-Bo Xue Qian Ye Liz Grant Jun-Xia Song Geoff Simm Jürg Utzinger Xiao-Kui Guo Xiao-Nong Zhou | 2022 | Infectious Diseases of Poverty2022，11，3： | 3 |
| 2 | Combustion synthesis and photoluminescence of perovskite PbTiOs nanopowders 显示文摘 | Liu S W Xiu Z L Liu J | 2007 | Journal of Alloys and Compounds2007，441，12： | 1 |
| 3 | The transcriptional reprcssor HBP1 is a target of the p38 mitogen-activated protein kinase pathway in cell cycle regulation显示文摘 | Xiu M Kim J Sampson E | 2003 | Mol Call Biol2003，23，23： | 1 |
| 4 | Controlled synthesis of high-quality PbS star-shaped dendrites,multipods,truncated nanocubes,and nanocubes and their shape evolution process显示文摘 | Zhou G J Lu M K Xiu Z L | 2006 | J Phys Chem B2006，110，13： | 1 |
| 5 | Some projection-like methods for the generalized Nash equilibria显示文摘 | Zhang J Z Qu B Xiu N H | 2010 | Comput Optim Appl2010，45，1： | 1 |
| 6 | A Novel All- Digital PLL With Software Adaptive Filter显示文摘 | Liming Xiu Wen Li Meiners J | 2004 | IEEE Journal of solid-state circuits2004，39，3： | 1 |
| 7 | Some recent advances in projection-type methods for variational inequalities显示文摘 | Xiu N Zhang J | 2003 | J Computational and Applied Mathematics2003，152，： | 1 |
| 8 | Decitabine reduces transfusion dependence in older patients with acute myeloid leukemia:results from a post hoc analysis of a randomized phase DI study显示文摘 | He J Xiu L De Porre P | 2014 | Leuk Lymphoma2014，56，4： | 1 |
| 9 | Local convergence analysis of projection type algorithms: Unified approach显示文摘 | Xiu N H Zhang J Z | 2002 | J Optim Theory Appl2002，，115： | 1 |
| 10 | Post anthesis dry matter accumulation and redis-tribution in spring wheat mulched with plastic film显示文摘 | Xiu J Y Gan J W | 1998 | Crop Science1998，38，： | 1 |
| 11 | The influence of tempering temperature on the reversed austenite formation and tensile properties in Fe-13% Cr-4% Ni-Mo low carbon martensite stainless steels 显示文摘 | Yuan Y S Xiu Y L Li J R Yi Li | 2011 | Materials Science and Engineering A2011，528，： | 1 |
| 12 | Copper and Zn uptake by radish and pakchoi as affected by application of livestock and poultry manures 显示文摘 | Dong M Z Xiu Z H Yu J W | 2005 | Chemosphere2005，59，2： | 1 |
| 13 | Differential effect of com- mon ligands and molecular oxygen on antimicrobial ac- tivity of silver nanoparticles versus silver ions 显示文摘 | Xiu Z M Ma J Alvarez P J | 2011 | En- vironmental Science & Technology2011，45，20： | 1 |
| 14 | A family of super- memory gradient projection methods for constrained opti- mization 显示文摘 | WANG Y J WANG C Y XIU N I-I | 2002 | Optimization2002，51，6： | 1 |
| 15 | Phase formation of Al2O3/Ti(C,N)-NiTi composite显示文摘 | XIU Z M LAENG J SUN X D LI Q HUR S K LIU Y N | 2008 | Journal of Alloys and Compounds2008，458，12： | 1 |
| 16 | Dynamic complexity of a two-prey one-predator system with impulsive effect显示文摘 | Zhang Y J Xiu Z L Chen L S | 2005 | Chaos Solitons and Fractals2005，26，： | 1 |
| 17 | Ultraviolet photoconductive detectors based on Ga-doped ZnO films grown by molecular beam epitaxy 显示文摘 | MANDALAPU L J XIU F YANG Z | 2007 | SolidState Electron2007，51，7： | 1 |
| 18 | Microstructures and thermoelectric properties of p-type pseudo-binary Bi-Sb-Te alloys with partial substitution of Ga for Sb prepared by spark plasma sintering显示文摘 | Cui J L Xue H F Xiu W J | 2006 | Materials Science and Engineering B2006，135，： | 1 |
| 19 | Copper and Zn up take by radish and pakchoi as affected by application of livestock and poultry manures显示文摘 | Dong M Z Xiu Z H Yu J W | 2005 | Chem osphere2005，59，2： | 1 |
| 20 | Modified extragrdient method for variational inequalities and verification of solution existence显示文摘 | WANG Y J XIU N H ZHANG J Z | 2003 | Journal of Optimization Theory and Applications2003，119，1： | 1 |
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