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| 1 | 地塞米松玻璃体腔植入剂治疗中国患者视网膜静脉阻塞继发黄斑水肿的安全性和有效性:随机、假注射对照、多中心研究显示文摘目的 评估地塞米松玻璃体腔植入物(DEX)治疗中国患者视网膜静脉阻塞继发黄斑水肿(RVO-ME)的安全性和有效性.方法 为期6个月的随机、双盲、假注射对照、多中心、3期临床研究,此后接续为期2个月的开放标签的延展研究.视网膜分支(BRVO)或中央静脉阻塞(CRVO)患眼于基线时接受DEX植入(n=129)或假注射(n=130)治疗;治疗后6个月时,两组中满足再治疗标准的全部患眼均再次接受DEX植入治疗.有效性变量包括最佳矫正视力(BCVA)和黄斑中心凹视网膜厚度(CRT).BCVA检查采用早期治疗糖尿病视网膜病变研究组视力表进行.光相干断层扫描(OCT)检查采用德国Heidelberg公司Spectralis OCT仪或德国Zeiss公司Cirrus OCT仪进行.结果 治疗后6个月中(主要终点),DEX治疗组BCVA较基线提高≥15个字母的时间早于假注射组(P<0.001).治疗后第2个月时(效应峰值),DEX治疗组、假注射组BCVA较基线提高≥15个字母患者百分比分别为34.9%,11.5%.DEX治疗组、假注射组平均BCVA较基线分别提高(10.6±10.4)、(1.7±12.3)个字母;平均CRT分别较基线下降(407±212)、(62±224) μm (P<0.001).DEX治疗组CRVO、BRVO患眼治疗效果均优于假注射组.主要常见治疗相关不良事件为眼压升高,均可通过局部降眼压药物控制;无患者需要接受抗青光眼手术.结论 DEX治疗中国患者RVO-ME具有良好的安全性和显著的临床疗效;单次植入DEX较假注射可获得持续3-4个月的视力和解剖结构改善. | 黎晓新 王宁利 梁小玲 徐格致 Xiao-yan Li Jenny Jiao Jean Lou Yehia Hashad | 2018 | 中华眼底病杂志2018，34，3： | 41 |
| 2 | Management of tear trough deformity with and without tear trough-orbicularis retaining ligament complex release in transconjunctival blepharoplasty: a comparative study显示文摘AIM: To evaluate the effect of releasing the orbicularis retaining ligament(ORL) complex of the tear trough combined with the transconjunctival blepharoplasty in the surgical management of tear trough deformity compared with the effect of blepharoplasty alone. METHODS: A prospective, randomized(by closed envelope technique), controlled surgical trial which included 50 patients(100 eyes) with bilateral visible tear trough deformity and lower eyelid fat bulging, was divided into two groups where 25 patients(50 eyes) had tear trough-ORL release with blepharoplasty and 25 patients(50 eyes) didn't. Qualitative and quantitative assessments of tear trough deformity were done at 6 mo postoperatively, achieving grade 0 or 1 of Barton's classification was considered a success. Standardized photographic documentation of each patient was done pre and postoperatively, also assessment of the patients' satisfaction postoperatively was done and ranked as excellent, very good, good or fair. RESULTS: There was statistically significant difference between the two groups in the overall aesthetic results postoperatively regarding the qualitative and quantitative analysis of the tear trough deformity, where patients who had tear trough-ORL complex release had more successful outcomes than those of the second group. CONCLUSION: ORL release should be done in patients with tear trough deformity in order to release the tethering effect of this ligament which causes the prominence of the naso jugal groove. | Tamer Ismail Gawdat Engy Abd Eltawab Elsherif Yomna Amr Alahmadawy Yehia Salah Eldin Mostafa | 2019 | International Journal of Ophthalmology(English edition)2019，12，1： | 12 |
| 3 | Hepato-cardiac disorders显示文摘Understanding the mutual relationship between the liver and the heart is important for both hepatologists and cardiologists. Hepato-cardiac diseases can be classified into heart diseases affecting the liver, liver diseases affecting the heart, and conditions affecting the heart and the liver at the same time. Differential diagnoses of liver injury are extremely important in a cardiologist's clinical practice calling for collaboration between cardiologists and hepatologists due to the many other diseases that can affect the liver and mimic haemodynamic injury. Acute and chronic heart failure may lead to acute ischemic hepatitis or chronic congestive hepatopathy. Treatment in these cases should be directed to the primary heart disease. In patients with advanced liver disease, cirrhotic cardiomyopathy may develop including hemodynamic changes, diastolic and systolic dysfunctions, reduced cardiac performance and electrophysiological abnormalities. Cardiac evaluation is important for patients with liver diseases especially before and after liver transplantation. Liver transplantation may lead to the improvement of all cardiac changes and the reversal of cirrhotic cardiomyopathy. There are systemic diseases that may affect both the liver and the heart concomitantly including congenital, metabolic and inflammatory diseases as well as alcoholism. This review highlights these hepatocardiac | Yasser Mahrous Fouad Reem Yehia | 2014 | World Journal of Hepatology2014，6，1： | 10 |
| 4 | 埃及尼罗河三角洲城市化监测显示文摘对1972、1984和1990年在尼罗河三角洲获取的Landsat MSS和TM影象(scenes)处理的和协同配准的(coregistered)数字镶嵌图比较表明,城镇增长正危及着埃及农业的生产力。在1972、1984和1990年尼罗河三角洲的城镇面积至少分别占3.6%、4.7%和5.7%,在这18年期间增长了58%。大约一半的增长出现在1984~1990年期间。如果这种趋势继续下去,到2010年埃及将因城市化而丧失农地总面积的12%。尽管事实上城镇增长主要出现在城市周围,但在几千个小村庄周围的增长却对尼罗河三角洲的农业生产构成最大的威胁。1972~1990年间,城市和大村庄的累积增长率为37%,而同期小村庄的累积增长率为77%。 | Mohamed Sultan Michael Fiske Thomas Stein Mohamed Gamal Yehia Abdel Hady Hesham El Araby Ahmed Madani Salah Mehanee Richard Becker 石培礼 | 1999 | AMBIO-人类环境杂志1999，28，7： | 9 |
| 5 | MTP genetic variants associated with non-alcoholic fatty liver in metabolic syndrome patients显示文摘This study was performed for investigation the relationship between variants of MTP gene polymorphism and the development of NAFLD in patients with and without MS.The study was included 174 NAFLD patients(106 with MS and 68 without MS),and 141 healthy control subjects.The 493 G/T polymorphism of MTP gene was evaluated by PCR-RFLP method.The frequency of MTP TT genotype and T allele were significantly higher in NAFLD patients when compared to healthy controls.Moreover,a significant association in MTP gene polymorphism was observed in NAFLD patients with MS compared to NAFLD patients without MS and controls.Our study suggested that MTP 493 G/T gene polymorphism may act as susceptibility biomarker for NAFLD and MS. | Weaam Gouda Esmat Ashour Yehia Shaker Wafaa Ezzat | 2017 | Genes & Diseases2017，4，4： | 4 |
| 6 | Epidemiological and clinical characteristics of inflammatory bowel diseases in Cairo,Egypt显示文摘AIM:To study the natural history,patterns and clinical characteristics of inflammatory bowel diseases(IBD)in Egypt.METHODS:We designed a case-series study in the gastroenterology centre of the Internal Medicine department of Cairo University,which is a tertiary care referral centre in Egypt.We included all patients in whom the diagnosis of ulcerative colitis(UC)or Crohn’s disease(CD)was confirmed by clinical,laboratory,endoscopic,histological and/or radiological criteria over the 15 year period from 1995 to 2009,and we studied their sociodemographic and clinical characteristics.Endoscopic examinations were performed by 2 senior experts.This hospital centre serves patients from Cairo,as well as patients referred from all other parts of Egypt.Our centre received 24156 patients over the described time period for gastro-intestinal consultations and/or interventions.RESULTS:A total of 157 patients with established IBD were included in this study.Of these,135 patients were diagnosed with UC(86%of the total),and 22patients,with CD(14%of the total).The mean ages at diagnosis were 27.3 and 29.7,respectively.Strikingly,we noticed a marked increase in the frequency of both UC and CD diagnoses during the most recent 10 years of the 15 year period studied.Regarding the gender distribution,the male:female ratio was 1:1.15 for UC and 2.6:1 for CD.The mean duration of follow up for patients with UC was 6.2±5.18 years,while the mean duration of follow up for patients with CD was 5.52±2.83 years.For patients with UC we found no correlation between the severity of the disease and the presence of extraintestinal manifestations.Eleven patients had surgical interventions during the studied years:4cases of total colectomy and 7 cases of anal surgery.CONCLUSION:We observed a ratio of 6:1 for UC to CD in our series.The incidence of IBD seems to be rising in Egypt. | Serag Esmat Mohamed El Nady Mohamed Elfekki Yehia Elsherif Mazen Naga | 2014 | World Journal of Gastroenterology2014，20，3： | 3 |
| 7 | Flash vacuum pyrolysis of azo and nitrosophenols: new routes towards hydroxyaryl nitrenes and their reactions 显示文摘 | Yehia A I | 2003 | Tetrahedron2003，59，29： | 1 |
| 8 | Alkali Reductive Roasting of Ilmenite Ore显示文摘 | El-Tawil S Z Mosri I M Yehia A Francis A A | 1996 | Canadian Metallurgical Quarterly1996，35，1： | 1 |
| 9 | Estimation of roll press design parameters based on the assessment of a particular nip region显示文摘 | Khaled Ahmed Yehia | 2007 | Powder Technology2007，，3： | 1 |
| 10 | Conductive Concrete Overlay for Bridge Deck Deicing 显示文摘 | Sherif Yehia Christopher Y Tuan | 1999 | ACI Materials Journal1999，96，3： | 1 |
| 11 | NPHS2 mutations 显示文摘 | Bakr A Yehia S El- Ghannam D | 2008 | Indian J Pediatr2008，75，2： | 1 |
| 12 | Acute renal failure in patients with pre-existing renal dysfunction following coronary artery bypass grafting显示文摘 | Yehia M Collins JF Beca J | 2005 | Nephrology2005，10，： | 1 |
| 13 | Mycobacterium tuberculosis infection inliver transplantation显示文摘 | Yehia BR Blumberg EA | 2010 | Liver Transpl2010，16，10： | 1 |
| 14 | Conductive Concrete Overlay for Bridge deck Deieing显示文摘 | Sherif Yehia Christopher Y Tuan | 1999 | ACI Materials Journal1999，96，3： | 1 |
| 15 | Computational slrategies for nonlinear and fracture mechanics problems: automatic crack propagation tracking显示文摘 | Mark S Shephard Nabil A B Yehia Gary S Burd | 1985 | Computer & Structure1985，20，： | 1 |
| 16 | Recycling of rubber waste显示文摘 | Abbas A Yehia A A | 2004 | Polym Plast Technol Eng2004，43，6： | 1 |
| 17 | The spectrum of fungal infections with a special referenceto dermatophytoses in the capital area of Kuwait during 2000-2005显示文摘 | Yehia MA El-Ammawi TS AI-Mazidi KM | 2010 | Mycopatholoqia2010，169，4： | 1 |
| 18 | Conductive Concrete Overlay for Bridge Deck Deicing: Mixture Proportioning, Optimization, and Properties 显示文摘 | Sherif Yehia Christopher Y Tuan David Ferdon | 2000 | ACI Materials Journal2000，97，2： | 1 |
| 19 | Transcriptional regulation of cyclin D2 by the PKA pathway and inducible cAMP early repressor in granulosa cells 显示文摘 | Muniz LC Yehia G Memin E | 2006 | Biol Reprod2006，75，2： | 1 |
| 20 | Conductive concrete overlay for bridge deck deicing: mixture proportioning, optimization, and properties 显示文摘 | Yehia S Tuan C Y Ferdon D | 2000 | ACI Materials Journal2000，97，2： | 1 |
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