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| 1 | 儿童重症监护中血糖控制与器官功能衰竭和病死率的关系显示文摘目的研究机械通气患几发生高血糖与器官功能衰竭的关系;介绍澳大利亚和新西兰PICU控制血糖的方法与实践。设计前瞻性队列研究。场所澳大利亚和新西兰的全部9家专业PICU病房。对象机械通气〉12h的患儿,但除外以下情况:合并糖尿病酮症酸中毒;家庭机械通气;入院时经积极心肺复苏;签有“不予复苏”医嘱。干预无。测量指标和主要结果所有患儿的血糖最长监测时间为14d,用临床和实验室指标计算儿童logistic器官功能障碍评分(PELOD)。研究中共有409例患儿使用了胰岛素。50%的患儿血糖值〉6.1mmol/L,同时89%患儿的血糖峰值〉6.1mmol/L,达到峰值的时间中位数是7h。在血糖-时间曲线上,采样时间中位数对应的曲线下面积〉6.1mmol/睹被定义为高血糖。高血糖患儿病死率为13%,而无高血糖者病死率为3%。高血糖和高PELOD(≥10)呈独立相关(OR值为3.41,95%CI:1.91~6.10)。高血糖与病死率也呈独立相关(OR值为3.31,95%CI:1.26~7.70)。早期高血糖(最初48h内)与上述预后亦相关,但与1d后PELOD加重和2d后PELOD≥10无关。5%的息儿接受了胰岛素治疗。结论高血糖在PICU较常见,通常出现较早,并与器官功能衰竭和死亡呈独立相关。但早期高血糖与晚发或加重的器官功能衰竭无关。澳大利亚和新西兰的PICU很少使用胰岛素。 | Yung M Wilkins B Slater A | 2008 | 中国小儿急救医学2008，15，2： | 8 |
| 2 | Toxicity and Carcinogenicity of Ozone in Combination with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and Dibutyl Phthalate in B6C3F1 Mice for 16 and 32 Weeks显示文摘To evaluate the toxic and carcinogenic potential of ozone alone or in combination with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone(NNK) and/or dibutyl phthalate(DBP).Methods Male and female B6C3F1 mice were exposed,through inhalation,intravenous administration and diet,to 0.5 ppm of ozone,1.0 mg/kg of NNK and 5000 ppm of DBP,individually and in combination for 16 and 32 weeks.Results No treatment-related death was seen,but significant differences in body and organ weights between control and treated mice were observed during the study.No incidence of lung tumor incidence was recorded in mice exposed to either ozone alone or combined treatment.Oviductal carcinomas were observed in female mice exposed to ozone or DBP alone for 16 weeks and ozone in combination with NNK and DBP for 32 weeks.Conclusion Although ozone alone and in conjunction with NNK and/or DBP does not induce lung cancer under our experimental conditions,they induce oviductal carcinomas in B6C3F1 mice. | MIN YOUNG KIM M YUNG CHO | 2009 | Biomedical and Environmental Sciences2009，22，3： | 3 |
| 3 | Prevalence of large cavum septi pellucidi in ultra high-risk individuals and patients with psychotic disorders显示文摘 | Takahashi T Yung AR Yücel M | 2008 | Schizophr Res2008，105，13： | 1 |
| 4 | Genetic algorithm solution for a risk-based partner selection problem in a virtual enterprise 显示文摘 | Ip W H Huang M Yung K L | 2003 | Computers & Operations Research2003，30，2： | 1 |
| 5 | Applications of genetic search and simulated annealing to the two-dimensional non-guillotine cutting stock problem显示文摘 | Leung T W Yung C H Tmutt M D | 2001 | Computers & Industrial Engineering2001，40，3： | 1 |
| 6 | Differentiation of Hunmn Embryonic Stem Cells into Corneal Epithelia|-like Cells by In Vitro Replication of theComeal Epithelial Stem Cell Niche 显示文摘 | Ahtnad S Stewart R Yung S Kolli S Armstrong L Stojkovie M Figueiredo F IAko M | 2007 | StemCells2007，255，： | 1 |
| 7 | The use of hydroxyapatite granules in mastoid obliteration 显示文摘 | Yung M W | 1996 | Clin Otolaryngol1996，21，6： | 1 |
| 8 | XPS investigation of Upilex-S polyimide ablated by 355 nm Nd:YAG laser irradiation显示文摘 | Yung K C Zeng D W Yue T M | 2001 | Applied Sur face Science2001，173，3： | 1 |
| 9 | Cu(OH)2- modified TiO2 nanotube arrays for efficient photocatalytic hydrogen production 显示文摘 | ZHANGSS WANGH J YUNG M S etal | 2013 | International Journal of Hydrogen Energy2013，38，18： | 1 |
| 10 | Epstein-Barr virus associated post-trasplatation lymphoproliferative disorder following lung transplantation is more commonly of host origin显示文摘 | PETERSON M R EMERY S C YUNG G L | 2006 | Arch Pathol Lab Med2006，130，2： | 1 |
| 11 | Analysis of the results of surgical endoscopic dacryocystorhinostomy:effect of the level of obstruction显示文摘 | YUNG M W HARDMAN-LEA S | 2002 | Br J Ophthalmol2002，86，7： | 1 |
| 12 | Genetic algorithm solution for a risk-based partner selection problem in a virtual enterprise显示文摘 | Ip W H Huang M Yung K L Wang D W | 2003 | Computers Operations Research2003，30，： | 1 |
| 13 | Machining of an aluminum/SiC composite using diamond inserts显示文摘 | Caroline J E Andrewes His Yung Feng Lau W M | 2000 | Journal of Materials Processing Technology2000，，102： | 1 |
| 14 | Heterogenous reactions with NaC1 in the EL chicheon volcanic aerosols 显示文摘 | Michelangeli D V Allen M Yung Y L | 1991 | Geophys Res Lett1991，18，： | 1 |
| 15 | Targeting gonadotropin-releasing hormone receptor inhibits the early step of ovarian cancer metastasis by modulating tumor-mesothelial adhesion显示文摘 | CHEUNG L W YUNG S CHAN T M | 2013 | Mol Ther2013，21，1： | 1 |
| 16 | A retrospective clinical study of urinary neural thread protein in Alzheimer' s disease 显示文摘 | Munzar M McConville M Yung J | 2002 | Alzheimer''s Rep2002，5，： | 1 |
| 17 | Adaptive impedance control of a haptic interface显示文摘 | Heon Park Jang M yung Lee | 2004 | Mechatronics2004，，14： | 1 |
| 18 | Contemporary methicillin-resistant Staphylococcus aureus clone in Hong Kong显示文摘 | Ip M Yung RWH Ng TK | 2005 | J Clin Microbiol2005，43，10： | 1 |
| 19 | Prospective randomised study of effect of octreotide on rebleeding from oesophageal varices after endoscopic ligation显示文摘 | SUNG J J CHUNG S C YUNG M Y | 1995 | Lancet1995，364，： | 1 |
| 20 | Preparation and properties ofhollow glass microsphere-filled epoxy-matrix composites显示文摘 | Yung K C Zhu B L Yue T M | 2009 | Composites Science and Technology2009，69，2： | 1 |
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